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Proposal to Revise the Screening Test for Latent Tuberculosis Infection in Close Contacts at Elementary Schools in Korea.
J Prev Med Public Health. 2019 Jul; 52(4):272-275.JP

Abstract

The 2018 National Guideline for Tuberculosis Control, which was published by the Korea Centers for Diseases Prevention and Control (KCDC), mandates conducting an epidemiological survey among close contacts of active tuberculosis patients at public institutions such as schools. In the procedure for these surveys, the tuberculin skin test (TST) is mandated as the screening test for latent tuberculosis infection in elementary school students. However, several guidelines recommend using the interferon-gamma releasing assay (IGRA) for contacts aged over 5 years with a Bacillus Calmette-Guérin vaccination history. The main reason for this is that IGRA has a higher specificity and lower false positive rate than TST. In addition, IGRA requires only a single visit to draw blood and the results are available within 24 hours. These advantages could promote cooperation from both parents and students in conducting these surveys. Thus, these findings regarding the benefits of IGRA for surveys of close contacts at elementary schools should be incorporated into the KCDC guideline.

Authors+Show Affiliations

Department of Preventive Medicine, Jeju National University School of Medicine, Jeju, Korea.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31396382

Citation

Bae, Jong-Myon. "Proposal to Revise the Screening Test for Latent Tuberculosis Infection in Close Contacts at Elementary Schools in Korea." Journal of Preventive Medicine and Public Health = Yebang Uihakhoe Chi, vol. 52, no. 4, 2019, pp. 272-275.
Bae JM. Proposal to Revise the Screening Test for Latent Tuberculosis Infection in Close Contacts at Elementary Schools in Korea. J Prev Med Public Health. 2019;52(4):272-275.
Bae, J. M. (2019). Proposal to Revise the Screening Test for Latent Tuberculosis Infection in Close Contacts at Elementary Schools in Korea. Journal of Preventive Medicine and Public Health = Yebang Uihakhoe Chi, 52(4), 272-275. https://doi.org/10.3961/jpmph.19.043
Bae JM. Proposal to Revise the Screening Test for Latent Tuberculosis Infection in Close Contacts at Elementary Schools in Korea. J Prev Med Public Health. 2019;52(4):272-275. PubMed PMID: 31396382.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Proposal to Revise the Screening Test for Latent Tuberculosis Infection in Close Contacts at Elementary Schools in Korea. A1 - Bae,Jong-Myon, Y1 - 2019/05/08/ PY - 2019/02/24/received PY - 2019/05/08/accepted PY - 2019/8/10/entrez PY - 2019/8/10/pubmed PY - 2019/8/10/medline KW - Interferon-gamma release tests KW - Latent tuberculosis KW - Mycobacterium tuberculosis KW - Practice guideline KW - Tuberculin test SP - 272 EP - 275 JF - Journal of preventive medicine and public health = Yebang Uihakhoe chi JO - J Prev Med Public Health VL - 52 IS - 4 N2 - The 2018 National Guideline for Tuberculosis Control, which was published by the Korea Centers for Diseases Prevention and Control (KCDC), mandates conducting an epidemiological survey among close contacts of active tuberculosis patients at public institutions such as schools. In the procedure for these surveys, the tuberculin skin test (TST) is mandated as the screening test for latent tuberculosis infection in elementary school students. However, several guidelines recommend using the interferon-gamma releasing assay (IGRA) for contacts aged over 5 years with a Bacillus Calmette-Guérin vaccination history. The main reason for this is that IGRA has a higher specificity and lower false positive rate than TST. In addition, IGRA requires only a single visit to draw blood and the results are available within 24 hours. These advantages could promote cooperation from both parents and students in conducting these surveys. Thus, these findings regarding the benefits of IGRA for surveys of close contacts at elementary schools should be incorporated into the KCDC guideline. SN - 2233-4521 UR - https://www.unboundmedicine.com/medline/citation/31396382/Proposal_to_Revise_the_Screening_Test_for_Latent_Tuberculosis_Infection_in_Close_Contacts_at_Elementary_Schools_in_Korea_ DB - PRIME DP - Unbound Medicine ER -
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