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Surgical approaches for infratemporal fossa tumor resection: Fifteen years' experience of a single center.
Head Neck 2019; 41(11):3755-3763HN

Abstract

BACKGROUND

The aims of this study were to report our center's experience with infratemporal fossa (ITF) tumors, to review the treatment modalities and outcomes.

METHODS

Data of patients that underwent resection of ITF tumors in a single tertiary referral medical center were collected and analyzed.

RESULTS

Sixty-three patients were included. Sarcoma was the most common pathology (18; 29%). The most common surgical approach was the preauricular-orbitozygomatic approach (24; 38%), followed by endoscopic, craniofacial resection, and combined approaches. Forty-seven patients (75%) required reconstruction, 23 (49%) involving free tissue transfer. Thirty-five patients (76%) with malignant lesions required adjuvant therapy consisting of radiotherapy, chemotherapy, or both. Thirty-three patients suffered from complications related to surgery or adjuvant therapy. The three- and five-years survival rates for malignancy were 82% and 66%, respectively.

CONCLUSION

Complete surgical resection of ITF involving tumors is feasible, providing good long-term survival. Multidisciplinary approach is the key for success.

Authors+Show Affiliations

Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Plastic and Reconstructive Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Plastic and Reconstructive Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Neurosurgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31407445

Citation

Yafit, Daniel, et al. "Surgical Approaches for Infratemporal Fossa Tumor Resection: Fifteen Years' Experience of a Single Center." Head & Neck, vol. 41, no. 11, 2019, pp. 3755-3763.
Yafit D, Duek I, Abu-Ghanem S, et al. Surgical approaches for infratemporal fossa tumor resection: Fifteen years' experience of a single center. Head Neck. 2019;41(11):3755-3763.
Yafit, D., Duek, I., Abu-Ghanem, S., Ungar, O. J., Wengier, A., Moshe-Levyn, H., ... Fliss, D. M. (2019). Surgical approaches for infratemporal fossa tumor resection: Fifteen years' experience of a single center. Head & Neck, 41(11), pp. 3755-3763. doi:10.1002/hed.25906.
Yafit D, et al. Surgical Approaches for Infratemporal Fossa Tumor Resection: Fifteen Years' Experience of a Single Center. Head Neck. 2019;41(11):3755-3763. PubMed PMID: 31407445.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surgical approaches for infratemporal fossa tumor resection: Fifteen years' experience of a single center. AU - Yafit,Daniel, AU - Duek,Irit, AU - Abu-Ghanem,Sara, AU - Ungar,Omer J, AU - Wengier,Anat, AU - Moshe-Levyn,Helena, AU - Yanko-Arzi,Ravit, AU - Zaretski,Arik, AU - Margalit,Nevo, AU - Abergel,Avraham, AU - Muhanna,Nidal, AU - Fliss,Dan M, Y1 - 2019/08/12/ PY - 2018/11/12/received PY - 2019/06/01/revised PY - 2019/07/19/accepted PY - 2019/8/14/pubmed PY - 2019/8/14/medline PY - 2019/8/14/entrez KW - fronto-orbitozygomatic approach KW - infratemporal fossa KW - skull base SP - 3755 EP - 3763 JF - Head & neck JO - Head Neck VL - 41 IS - 11 N2 - BACKGROUND: The aims of this study were to report our center's experience with infratemporal fossa (ITF) tumors, to review the treatment modalities and outcomes. METHODS: Data of patients that underwent resection of ITF tumors in a single tertiary referral medical center were collected and analyzed. RESULTS: Sixty-three patients were included. Sarcoma was the most common pathology (18; 29%). The most common surgical approach was the preauricular-orbitozygomatic approach (24; 38%), followed by endoscopic, craniofacial resection, and combined approaches. Forty-seven patients (75%) required reconstruction, 23 (49%) involving free tissue transfer. Thirty-five patients (76%) with malignant lesions required adjuvant therapy consisting of radiotherapy, chemotherapy, or both. Thirty-three patients suffered from complications related to surgery or adjuvant therapy. The three- and five-years survival rates for malignancy were 82% and 66%, respectively. CONCLUSION: Complete surgical resection of ITF involving tumors is feasible, providing good long-term survival. Multidisciplinary approach is the key for success. SN - 1097-0347 UR - https://www.unboundmedicine.com/medline/citation/31407445/Surgical_approaches_for_infratemporal_fossa_tumor_resection:_Fifteen_years'_experience_of_a_single_center L2 - https://doi.org/10.1002/hed.25906 DB - PRIME DP - Unbound Medicine ER -