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Prevalence and Correlates of Depressive Symptomology among Young Adults Who Use Prescription Opioids Non-medically.
J Psychoactive Drugs. 2019 Nov-Dec; 51(5):441-452.JP

Abstract

Non-medical prescription opioid (NMPO) use and depression frequently co-occur and are mutually reinforcing in adults, yet NMPO use and depression in younger populations has been under-studied. We examined the prevalence and correlates of depressive symptomology among NMPO-using young adults. The Rhode Island Young Adult Prescription Drug Study (RAPiDS) recruited young adults in Rhode Island who reported past 30-day NMPO use. We administered the Center for Epidemiologic Studies Short Depression Scale (CES-D 10), and used modified Poisson regression to identify the independent correlates of depressive symptomology (CES-D 10 score ≥10). Over half (59.8%, n = 119) screened positive for depressive symptomology. In modified Poisson regression analysis, diagnostic history of depressive disorder and childhood verbal abuse were associated with depressive symptomology. Participants with depressive symptomology were more likely to report using prescription opioids non-medically to feel less depressed or anxious, to avoid withdrawal symptoms, and as a substitute when other drugs are not available. Among young adult NMPO users, depressive symptomology is prevalent and associated with distinct motivations for engaging in NMPO use and represents a potential subgroup for intervention. Improving guidelines with tools such as screening for depressive symptomology among young adult NMPO users may help prevent NMPO-related harms.

Authors+Show Affiliations

Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.Division of Epidemiology, University of California Berkeley School of Public Health, Berkeley, CA, USA.Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA. Department of Emergency Medicine, Boston Medical Center Injury Prevention Center and Boston University School of Medicine, Boston, MA, USA. Department of Emergency Medicine, The Warren Alpert School of Medicine of Brown University, Rhode Island Hospital, Providence, RI, USA.Department of Pediatrics, Boston Medical Center, Boston, MA, USA. Department of Pediatrics, Division of General Pediatrics, Boston University School of Medicine, Boston, MA, USA.Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

31411548

Citation

Bouvier, Benjamin A., et al. "Prevalence and Correlates of Depressive Symptomology Among Young Adults Who Use Prescription Opioids Non-medically." Journal of Psychoactive Drugs, vol. 51, no. 5, 2019, pp. 441-452.
Bouvier BA, Kinnard EN, Yedinak JL, et al. Prevalence and Correlates of Depressive Symptomology among Young Adults Who Use Prescription Opioids Non-medically. J Psychoactive Drugs. 2019;51(5):441-452.
Bouvier, B. A., Kinnard, E. N., Yedinak, J. L., Li, Y., Elston, B., Green, T. C., Hadland, S. E., & Marshall, B. D. L. (2019). Prevalence and Correlates of Depressive Symptomology among Young Adults Who Use Prescription Opioids Non-medically. Journal of Psychoactive Drugs, 51(5), 441-452. https://doi.org/10.1080/02791072.2019.1654151
Bouvier BA, et al. Prevalence and Correlates of Depressive Symptomology Among Young Adults Who Use Prescription Opioids Non-medically. J Psychoactive Drugs. 2019 Nov-Dec;51(5):441-452. PubMed PMID: 31411548.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and Correlates of Depressive Symptomology among Young Adults Who Use Prescription Opioids Non-medically. AU - Bouvier,Benjamin A, AU - Kinnard,Elizabeth N, AU - Yedinak,Jesse L, AU - Li,Yu, AU - Elston,Beth, AU - Green,Traci C, AU - Hadland,Scott E, AU - Marshall,Brandon D L, Y1 - 2019/08/14/ PY - 2019/8/15/pubmed PY - 2020/6/13/medline PY - 2019/8/15/entrez KW - Prescription opioids KW - adolescents KW - depression KW - depressive symptomology KW - motivations KW - young adults SP - 441 EP - 452 JF - Journal of psychoactive drugs JO - J Psychoactive Drugs VL - 51 IS - 5 N2 - Non-medical prescription opioid (NMPO) use and depression frequently co-occur and are mutually reinforcing in adults, yet NMPO use and depression in younger populations has been under-studied. We examined the prevalence and correlates of depressive symptomology among NMPO-using young adults. The Rhode Island Young Adult Prescription Drug Study (RAPiDS) recruited young adults in Rhode Island who reported past 30-day NMPO use. We administered the Center for Epidemiologic Studies Short Depression Scale (CES-D 10), and used modified Poisson regression to identify the independent correlates of depressive symptomology (CES-D 10 score ≥10). Over half (59.8%, n = 119) screened positive for depressive symptomology. In modified Poisson regression analysis, diagnostic history of depressive disorder and childhood verbal abuse were associated with depressive symptomology. Participants with depressive symptomology were more likely to report using prescription opioids non-medically to feel less depressed or anxious, to avoid withdrawal symptoms, and as a substitute when other drugs are not available. Among young adult NMPO users, depressive symptomology is prevalent and associated with distinct motivations for engaging in NMPO use and represents a potential subgroup for intervention. Improving guidelines with tools such as screening for depressive symptomology among young adult NMPO users may help prevent NMPO-related harms. SN - 2159-9777 UR - https://www.unboundmedicine.com/medline/citation/31411548/Prevalence_and_Correlates_of_Depressive_Symptomology_among_Young_Adults_Who_Use_Prescription_Opioids_Non_medically_ L2 - https://www.tandfonline.com/doi/full/10.1080/02791072.2019.1654151 DB - PRIME DP - Unbound Medicine ER -