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Sinonasal relapses of a primary isolated extranodal NK/T-cell lymphoma of the testis.
BMJ Case Rep 2019; 12(8)BC

Abstract

WHO first recognised extranodal NK/T-cell lymphoma (ENKTCL) in 2001, thanks to technical advances in anatomopathology and immunohistochemistry. It is divided into nasal and extranasal subgroups depending on the primary site. Primary isolated NK/T-cell lymphoma of the testis is rare. Typical recurrence sites of primary testicular NK/T-cell lymphoma are the gastrointestinal tract, lymph nodes, skin, spleen and central nervous system. Nasal relapses of a primary NK/T-cell lymphoma of the testis are very rare and according to our knowledge, no other case has been reported yet in the literature. The authors report the case of a 35-year-old Caucasian man relapsing twice in the nasal cavity 1 year after initial diagnosis and treatment of a primary isolated, stage IE, ENKTCL of the testis. We report the clinical and radiological presentation of the nasal relapses and the different modalities of treatment that were applied. Sinonasal relapses of an isolated primary NK/T-cell lymphoma of the testis are very rare. ENKTCL is a very aggressive entity, even at an early stage, therefore, requiring a multimodal treatment approach including chemotherapy and radiotherapy. New strategies to treat this disease are needed.

Authors+Show Affiliations

Department of Otorhinolaryngology, Hospital of Sion, Sion, Switzerland.Hematology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.Department of Otorhinolaryngology, Hospital of Sion, Sion, Switzerland.Oncology, Hospital of Sion, Sion, Switzerland.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31413056

Citation

Hallak, Bassel, et al. "Sinonasal Relapses of a Primary Isolated Extranodal NK/T-cell Lymphoma of the Testis." BMJ Case Reports, vol. 12, no. 8, 2019.
Hallak B, Cairoli A, Bouayed S, et al. Sinonasal relapses of a primary isolated extranodal NK/T-cell lymphoma of the testis. BMJ Case Rep. 2019;12(8).
Hallak, B., Cairoli, A., Bouayed, S., & Berthod, G. (2019). Sinonasal relapses of a primary isolated extranodal NK/T-cell lymphoma of the testis. BMJ Case Reports, 12(8), doi:10.1136/bcr-2019-230221.
Hallak B, et al. Sinonasal Relapses of a Primary Isolated Extranodal NK/T-cell Lymphoma of the Testis. BMJ Case Rep. 2019 Aug 13;12(8) PubMed PMID: 31413056.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sinonasal relapses of a primary isolated extranodal NK/T-cell lymphoma of the testis. AU - Hallak,Bassel, AU - Cairoli,Anne, AU - Bouayed,Salim, AU - Berthod,Grégoire, Y1 - 2019/08/13/ PY - 2019/8/16/entrez PY - 2019/8/16/pubmed PY - 2019/8/16/medline KW - cancer - see oncology KW - ear, nose and throat KW - radiotherapy JF - BMJ case reports JO - BMJ Case Rep VL - 12 IS - 8 N2 - WHO first recognised extranodal NK/T-cell lymphoma (ENKTCL) in 2001, thanks to technical advances in anatomopathology and immunohistochemistry. It is divided into nasal and extranasal subgroups depending on the primary site. Primary isolated NK/T-cell lymphoma of the testis is rare. Typical recurrence sites of primary testicular NK/T-cell lymphoma are the gastrointestinal tract, lymph nodes, skin, spleen and central nervous system. Nasal relapses of a primary NK/T-cell lymphoma of the testis are very rare and according to our knowledge, no other case has been reported yet in the literature. The authors report the case of a 35-year-old Caucasian man relapsing twice in the nasal cavity 1 year after initial diagnosis and treatment of a primary isolated, stage IE, ENKTCL of the testis. We report the clinical and radiological presentation of the nasal relapses and the different modalities of treatment that were applied. Sinonasal relapses of an isolated primary NK/T-cell lymphoma of the testis are very rare. ENKTCL is a very aggressive entity, even at an early stage, therefore, requiring a multimodal treatment approach including chemotherapy and radiotherapy. New strategies to treat this disease are needed. SN - 1757-790X UR - https://www.unboundmedicine.com/medline/citation/31413056/Sinonasal_relapses_of_a_primary_isolated_extranodal_NK/T-cell_lymphoma_of_the_testis L2 - http://casereports.bmj.com/cgi/pmidlookup?view=long&pmid=31413056 DB - PRIME DP - Unbound Medicine ER -