Tags

Type your tag names separated by a space and hit enter

Serum immune complexes in erythema nodosum leprosum reactions of leprosy.
Indian J Lepr. 1988 Apr; 60(2):189-95.IJ

Abstract

Serum estimations of immunoglobulins, complement components and their presence in circulating immune complexes were carried out in 39 Lepromatous, 44 ENL and 22 Post ENL leprosy patients. Serum IgG, IgA, IgM, C3 and C4 levels were determined by single radial immunodiffusion. Serum immune complexes were precipitated with Polyethylene Glycol (PEG) and IgG, IgA, IgM, C3 and C4 were estimated by single radial immunodiffusion and expressed as % of precipitation of their serum level. Decreased IgG, IgM; increased IgA and C3; and no change in C4 levels are observed in ENL than Lepromatous and Post ENL patients. However, a gradual insignificant reduction of IgG, IgA, and IgM was found from Lepromatous to ENL and Post ENL patients in the PEG-precipitates. Similarly, C3 and C4 was found reduced insignificantly in ENL than Lepromatous and Post ENL patients. The significance of these estimations in relation to immune status of ENL reactions are discussed.

Authors+Show Affiliations

Department of Zoology, Osmania University, Hyderabad.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3142953

Citation

Rao, T D., and P R. Rao. "Serum Immune Complexes in Erythema Nodosum Leprosum Reactions of Leprosy." Indian Journal of Leprosy, vol. 60, no. 2, 1988, pp. 189-95.
Rao TD, Rao PR. Serum immune complexes in erythema nodosum leprosum reactions of leprosy. Indian J Lepr. 1988;60(2):189-95.
Rao, T. D., & Rao, P. R. (1988). Serum immune complexes in erythema nodosum leprosum reactions of leprosy. Indian Journal of Leprosy, 60(2), 189-95.
Rao TD, Rao PR. Serum Immune Complexes in Erythema Nodosum Leprosum Reactions of Leprosy. Indian J Lepr. 1988;60(2):189-95. PubMed PMID: 3142953.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum immune complexes in erythema nodosum leprosum reactions of leprosy. AU - Rao,T D, AU - Rao,P R, PY - 1988/4/1/pubmed PY - 1988/4/1/medline PY - 1988/4/1/entrez SP - 189 EP - 95 JF - Indian journal of leprosy JO - Indian J Lepr VL - 60 IS - 2 N2 - Serum estimations of immunoglobulins, complement components and their presence in circulating immune complexes were carried out in 39 Lepromatous, 44 ENL and 22 Post ENL leprosy patients. Serum IgG, IgA, IgM, C3 and C4 levels were determined by single radial immunodiffusion. Serum immune complexes were precipitated with Polyethylene Glycol (PEG) and IgG, IgA, IgM, C3 and C4 were estimated by single radial immunodiffusion and expressed as % of precipitation of their serum level. Decreased IgG, IgM; increased IgA and C3; and no change in C4 levels are observed in ENL than Lepromatous and Post ENL patients. However, a gradual insignificant reduction of IgG, IgA, and IgM was found from Lepromatous to ENL and Post ENL patients in the PEG-precipitates. Similarly, C3 and C4 was found reduced insignificantly in ENL than Lepromatous and Post ENL patients. The significance of these estimations in relation to immune status of ENL reactions are discussed. SN - 0254-9395 UR - https://www.unboundmedicine.com/medline/citation/3142953/Serum_immune_complexes_in_erythema_nodosum_leprosum_reactions_of_leprosy_ DB - PRIME DP - Unbound Medicine ER -