Tags

Type your tag names separated by a space and hit enter

Risk stratification of advanced colorectal neoplasia after baseline colonoscopy: Cohort study of 17 Japanese community practices.
Dig Endosc. 2020 Jan; 32(1):106-113.DE

Abstract

BACKGROUND AND AIM

In Japan, risk stratification after baseline colonoscopy is not widely accepted. We investigated the findings of baseline colonoscopies at 17 community practices and evaluated the risk of the incidence of advanced neoplasia over a 5-year period.

METHODS

This retrospective cohort study enrolled 3115 subjects over 40 years of age who underwent baseline colonoscopies and had at least one repeated colonoscopy within 5 years. Each group was classified based on the endoscopic findings of the baseline colonoscopy: no neoplasia/diminutive polyp <5 mm (N/D); small adenoma <10 mm; advanced adenoma; invasive cancer, respectively. We examined the incidence of advanced neoplasia during these 5 years and investigated the relationship between the surveillance colonoscopy and newly detected advanced neoplasia.

RESULTS

The small adenoma group did not show any significant increased risk as compared to the N/D group (hazard ratio [HR]: 0.799. 95% CI 0.442-1.443). There was a significantly increased risk in the advanced adenoma and invasive cancer groups (HR: 4.996, 95% CI 2.940-8.491, HR: 3.737, 95% CI 1.309-10.666). Cancer incidences during the study period were 0.18% in the N/D group, and 1.9% in the invasive cancer group, respectively. Undergoing surveillance colonoscopies twice within 5 years decreased the risk of advanced neoplasia.

CONCLUSIONS

There was a close relationship between the endoscopic findings of baseline colonoscopies and subsequent advanced neoplasia development. Risk stratification for advanced neoplasia based on the baseline findings can serve as a useful index for determining the optimal interval and frequency of colonoscopies over a 5-year period.

Authors+Show Affiliations

Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.Oda GI Endoscopy and Gastroenterology Clinic, Kumamoto, Japan.Nishimi Medical Clinic, Yamaguchi, Japan.Department of Medical Statistics, School of Medicine, Toho University, Tokyo, Japan.Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.Department of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31429986

Citation

Shono, Takashi, et al. "Risk Stratification of Advanced Colorectal Neoplasia After Baseline Colonoscopy: Cohort Study of 17 Japanese Community Practices." Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society, vol. 32, no. 1, 2020, pp. 106-113.
Shono T, Oyama S, Oda Y, et al. Risk stratification of advanced colorectal neoplasia after baseline colonoscopy: Cohort study of 17 Japanese community practices. Dig Endosc. 2020;32(1):106-113.
Shono, T., Oyama, S., Oda, Y., Yokomine, K., Murakami, Y., Miyamoto, H., Tanaka, M., Naoe, H., & Sasaki, Y. (2020). Risk stratification of advanced colorectal neoplasia after baseline colonoscopy: Cohort study of 17 Japanese community practices. Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society, 32(1), 106-113. https://doi.org/10.1111/den.13516
Shono T, et al. Risk Stratification of Advanced Colorectal Neoplasia After Baseline Colonoscopy: Cohort Study of 17 Japanese Community Practices. Dig Endosc. 2020;32(1):106-113. PubMed PMID: 31429986.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Risk stratification of advanced colorectal neoplasia after baseline colonoscopy: Cohort study of 17 Japanese community practices. AU - Shono,Takashi, AU - Oyama,Shinichiro, AU - Oda,Yasushi, AU - Yokomine,Kazunori, AU - Murakami,Yoshitaka, AU - Miyamoto,Hideaki, AU - Tanaka,Motohiko, AU - Naoe,Hideaki, AU - Sasaki,Yutaka, AU - ,, Y1 - 2019/11/07/ PY - 2019/03/28/received PY - 2019/08/15/accepted PY - 2019/8/21/pubmed PY - 2020/11/6/medline PY - 2019/8/21/entrez KW - advanced neoplasia KW - colorectal cancer KW - invasive cancer KW - risk stratification KW - surveillance colonoscopy SP - 106 EP - 113 JF - Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society JO - Dig Endosc VL - 32 IS - 1 N2 - BACKGROUND AND AIM: In Japan, risk stratification after baseline colonoscopy is not widely accepted. We investigated the findings of baseline colonoscopies at 17 community practices and evaluated the risk of the incidence of advanced neoplasia over a 5-year period. METHODS: This retrospective cohort study enrolled 3115 subjects over 40 years of age who underwent baseline colonoscopies and had at least one repeated colonoscopy within 5 years. Each group was classified based on the endoscopic findings of the baseline colonoscopy: no neoplasia/diminutive polyp <5 mm (N/D); small adenoma <10 mm; advanced adenoma; invasive cancer, respectively. We examined the incidence of advanced neoplasia during these 5 years and investigated the relationship between the surveillance colonoscopy and newly detected advanced neoplasia. RESULTS: The small adenoma group did not show any significant increased risk as compared to the N/D group (hazard ratio [HR]: 0.799. 95% CI 0.442-1.443). There was a significantly increased risk in the advanced adenoma and invasive cancer groups (HR: 4.996, 95% CI 2.940-8.491, HR: 3.737, 95% CI 1.309-10.666). Cancer incidences during the study period were 0.18% in the N/D group, and 1.9% in the invasive cancer group, respectively. Undergoing surveillance colonoscopies twice within 5 years decreased the risk of advanced neoplasia. CONCLUSIONS: There was a close relationship between the endoscopic findings of baseline colonoscopies and subsequent advanced neoplasia development. Risk stratification for advanced neoplasia based on the baseline findings can serve as a useful index for determining the optimal interval and frequency of colonoscopies over a 5-year period. SN - 1443-1661 UR - https://www.unboundmedicine.com/medline/citation/31429986/Risk_stratification_of_advanced_colorectal_neoplasia_after_baseline_colonoscopy:_Cohort_study_of_17_Japanese_community_practices_ L2 - https://doi.org/10.1111/den.13516 DB - PRIME DP - Unbound Medicine ER -