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New insights and rethinking of cinnabar for chemical and its pharmacological dynamics.
Bioengineered 2019; 10(1):353-364B

Abstract

Cinnabar is an attractive mineral with many different uses. It is reported that cinnabar is one of the traditional Chinese's medicines extensively use. The main objective of this critical review is to identify the current overview, concept and chemistry of cinnabar, which includes the process developments, challenges, and diverse options for pharmacology research. It is used as a medicine through probable toxicity, especially when taking overdoes. This review is the first to describe the toxicological effects of cinnabar and its associated compounds. Nuclear magnetic resonance (NMR) dependent metabolomics could be useful for examination of the pharmaceutical consequence. The analysis indicated that the accurate preparation methods, appropriate doses, disease status, ages with drug combinations are significant factors for impacting the cinnabar toxicity. Toxicologically, synthetic mercury sulfide or cinnabar should be notable for mercuric chloride, mercury vapor and methyl mercury for future protection and need several prominent advancements in cinnabar research.

Authors+Show Affiliations

Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China. Bioresource Institute for Healthy Utilization, Zunyi Medical University , Guizhou , China.Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University , Guizhou , China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31431119

Citation

Jain, Archana, et al. "New Insights and Rethinking of Cinnabar for Chemical and Its Pharmacological Dynamics." Bioengineered, vol. 10, no. 1, 2019, pp. 353-364.
Jain A, Sarsaiya S, Wu Q, et al. New insights and rethinking of cinnabar for chemical and its pharmacological dynamics. Bioengineered. 2019;10(1):353-364.
Jain, A., Sarsaiya, S., Wu, Q., Shi, J., & Lu, Y. (2019). New insights and rethinking of cinnabar for chemical and its pharmacological dynamics. Bioengineered, 10(1), pp. 353-364. doi:10.1080/21655979.2019.1652491.
Jain A, et al. New Insights and Rethinking of Cinnabar for Chemical and Its Pharmacological Dynamics. Bioengineered. 2019;10(1):353-364. PubMed PMID: 31431119.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New insights and rethinking of cinnabar for chemical and its pharmacological dynamics. AU - Jain,Archana, AU - Sarsaiya,Surendra, AU - Wu,Qin, AU - Shi,Jingshan, AU - Lu,Yuanfu, PY - 2020/08/20/pmc-release PY - 2019/8/22/entrez PY - 2019/8/23/pubmed PY - 2019/8/23/medline KW - Cinnabar KW - medicine KW - mineral complex KW - pharmacology KW - toxicology SP - 353 EP - 364 JF - Bioengineered JO - Bioengineered VL - 10 IS - 1 N2 - Cinnabar is an attractive mineral with many different uses. It is reported that cinnabar is one of the traditional Chinese's medicines extensively use. The main objective of this critical review is to identify the current overview, concept and chemistry of cinnabar, which includes the process developments, challenges, and diverse options for pharmacology research. It is used as a medicine through probable toxicity, especially when taking overdoes. This review is the first to describe the toxicological effects of cinnabar and its associated compounds. Nuclear magnetic resonance (NMR) dependent metabolomics could be useful for examination of the pharmaceutical consequence. The analysis indicated that the accurate preparation methods, appropriate doses, disease status, ages with drug combinations are significant factors for impacting the cinnabar toxicity. Toxicologically, synthetic mercury sulfide or cinnabar should be notable for mercuric chloride, mercury vapor and methyl mercury for future protection and need several prominent advancements in cinnabar research. SN - 2165-5987 UR - https://www.unboundmedicine.com/medline/citation/31431119/New_insights_and_rethinking_of_cinnabar_for_chemical_and_its_pharmacological_dynamics L2 - http://www.tandfonline.com/doi/full/10.1080/21655979.2019.1652491 DB - PRIME DP - Unbound Medicine ER -