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A national study on the use of opioid analgesics in dentistry.
Braz Oral Res 2019; 33:e076BO

Abstract

The aim of this study was to assess the frequency of opioid analgesics prescribed by Brazilian dentists, potential regional differences and their association with socioeconomic and health-related factors. Data for all opioid prescriptions by dentists was obtained from the 2012 database of the National Controlled Substances Management System, regulated by the Brazilian Health Surveillance Agency. The number of defined daily doses (DDD) and DDDs per 1,000 inhabitants per day for each Brazilian state were calculated as the primary outcomes. DDDs were compared by regions and Brazilian states. Spearman's rho correlation coefficient was used to determine the influence of the states' characteristics, such as the Human Development Index; poverty; education; number of dentists per 100,000 inhabitants; visit to the dentist; dental care plan; good or very good oral health; number of pharmaceutical establishments per 100,000/inhabitants; and ability to get all prescribed medications. Data analysis was performed using IBM SPSS Statistics 25.0. A total of 141,161 prescriptions for opioids analgesics by 36,929 dentists were recorded, corresponding to 658,855 doses of opioids dispensed in 2012. The most commonly dispensed opioids were codeine associated with paracetamol (83.2%; n = 117,493). The national DDDs per 1,000 inhabitants per day was 0.0093 (range: 0.0002-0.0216). DDD per 1,000 inhabitants per day was positively associated to visits to dentists (rs = 0.630; P < 0.001) and inversely associated to poverty (rs = -0.624; p = 0.001). There are significant differences in opioid prescriptions in dentistry among the Brazilian states. These differences may be associated with non-clinical factors.

Authors+Show Affiliations

Universidade Federal de Minas Gerais - UFMG, School of Dentistry, Department of Community and Preventive Dentistry, Belo Horizonte, MG, Brazil.The University of Sidney, School of Medicine, Sidney, New South Wales, Australia.Boston University, Henry M. Goldman School of Dental Medicine , Department of Health Policy & Health Services Research, Boston, Massachusetts, USA.Universidade Federal de Minas Gerais - UFMG, School of Pharmacy, Department of Pharmaceutical Products, Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais - UFMG, School of Dentistry, Department of Operative Dentistry, Belo Horizonte, MG, Brazil.Universidade Federal de Minas Gerais - UFMG, School of Dentistry, Department of Community and Preventive Dentistry, Belo Horizonte, MG, Brazil.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31432927

Citation

Lino, Patrícia Azevedo, et al. "A National Study On the Use of Opioid Analgesics in Dentistry." Brazilian Oral Research, vol. 33, 2019, pp. e076.
Lino PA, Sohn W, Singhal A, et al. A national study on the use of opioid analgesics in dentistry. Braz Oral Res. 2019;33:e076.
Lino, P. A., Sohn, W., Singhal, A., Martins, M. A. P., Silva, M. E. S. E., & Abreu, M. H. N. G. (2019). A national study on the use of opioid analgesics in dentistry. Brazilian Oral Research, 33, pp. e076. doi:10.1590/1807-3107bor-2019.vol33.0076.
Lino PA, et al. A National Study On the Use of Opioid Analgesics in Dentistry. Braz Oral Res. 2019 Aug 15;33:e076. PubMed PMID: 31432927.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A national study on the use of opioid analgesics in dentistry. AU - Lino,Patrícia Azevedo, AU - Sohn,Woosung, AU - Singhal,Astha, AU - Martins,Maria Auxiliadora Parreiras, AU - Silva,Maria Elisa de Souza E, AU - Abreu,Mauro Henrique Nogueira Guimarães de, Y1 - 2019/08/15/ PY - 2019/02/21/received PY - 2019/06/11/accepted PY - 2019/8/22/entrez PY - 2019/8/23/pubmed PY - 2019/9/4/medline SP - e076 EP - e076 JF - Brazilian oral research JO - Braz Oral Res VL - 33 N2 - The aim of this study was to assess the frequency of opioid analgesics prescribed by Brazilian dentists, potential regional differences and their association with socioeconomic and health-related factors. Data for all opioid prescriptions by dentists was obtained from the 2012 database of the National Controlled Substances Management System, regulated by the Brazilian Health Surveillance Agency. The number of defined daily doses (DDD) and DDDs per 1,000 inhabitants per day for each Brazilian state were calculated as the primary outcomes. DDDs were compared by regions and Brazilian states. Spearman's rho correlation coefficient was used to determine the influence of the states' characteristics, such as the Human Development Index; poverty; education; number of dentists per 100,000 inhabitants; visit to the dentist; dental care plan; good or very good oral health; number of pharmaceutical establishments per 100,000/inhabitants; and ability to get all prescribed medications. Data analysis was performed using IBM SPSS Statistics 25.0. A total of 141,161 prescriptions for opioids analgesics by 36,929 dentists were recorded, corresponding to 658,855 doses of opioids dispensed in 2012. The most commonly dispensed opioids were codeine associated with paracetamol (83.2%; n = 117,493). The national DDDs per 1,000 inhabitants per day was 0.0093 (range: 0.0002-0.0216). DDD per 1,000 inhabitants per day was positively associated to visits to dentists (rs = 0.630; P < 0.001) and inversely associated to poverty (rs = -0.624; p = 0.001). There are significant differences in opioid prescriptions in dentistry among the Brazilian states. These differences may be associated with non-clinical factors. SN - 1807-3107 UR - https://www.unboundmedicine.com/medline/citation/31432927/A_national_study_on_the_use_of_opioid_analgesics_in_dentistry L2 - http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S1806-83242019000100257&amp;lng=en&amp;nrm=iso&amp;tlng=en DB - PRIME DP - Unbound Medicine ER -