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Autologous Blood Patch for Persistent Ascites Leak from Non-Closing Paracentesis Tracts.
Med Sci (Basel) 2019; 7(9)MS

Abstract

Ascites, the fluid accumulation in the peritoneal cavity, is most commonly seen in patients with end-stage liver disease (ESLD). Evaluating ascites or providing symptomatic relief for patients is accomplished by performing a paracentesis. Ascites leak from a paracentesis site can be a complication of the procedure and is associated with increased morbidity. Currently, the best options for these patients include medical management or surgical abdominal wall layer closure. Utilizing a blood patch provides an alternative approach to managing such patients. A two-center prospective case series was performed evaluating the efficacy of the blood patch in patients with significant persistent ascites leak following a paracentesis. About 30 mL of the patients' peripheral blood was used for the blood patch. Subjects were recruited over a period of one year and followed for 30 days after the procedure. A total of six patients were recruited for this study. Subjects underwent placement of autologous blood patch at the site of the ascites leak and 100% had resolution of the leak within 24 hours. None of the subjects developed any complications of the procedure. This study shows that an autologous blood patch is an effective, low-risk treatment method for ascites leaks following a paracentesis. It is a simple bedside procedure that can reduce morbidity in patients with end-stage liver disease.

Authors+Show Affiliations

Warren Alpert Medical School, Brown University, Rhode Island Hospital, Internal Medicine, 593 Eddy St, Providence, RI 02903, USA. nazkhan789@gmail.com.Warren Alpert Medical School, Brown University, Rhode Island Hospital, Pulmonary,Critical Care & Sleep Disorders 593 Eddy St, Providence, RI 02903, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31443552

Citation

Khan, Nazia, and Kevin M. Dushay. "Autologous Blood Patch for Persistent Ascites Leak From Non-Closing Paracentesis Tracts." Medical Sciences (Basel, Switzerland), vol. 7, no. 9, 2019.
Khan N, Dushay KM. Autologous Blood Patch for Persistent Ascites Leak from Non-Closing Paracentesis Tracts. Med Sci (Basel). 2019;7(9).
Khan, N., & Dushay, K. M. (2019). Autologous Blood Patch for Persistent Ascites Leak from Non-Closing Paracentesis Tracts. Medical Sciences (Basel, Switzerland), 7(9), doi:10.3390/medsci7090088.
Khan N, Dushay KM. Autologous Blood Patch for Persistent Ascites Leak From Non-Closing Paracentesis Tracts. Med Sci (Basel). 2019 Aug 22;7(9) PubMed PMID: 31443552.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Autologous Blood Patch for Persistent Ascites Leak from Non-Closing Paracentesis Tracts. AU - Khan,Nazia, AU - Dushay,Kevin M, Y1 - 2019/08/22/ PY - 2019/06/14/received PY - 2019/08/16/revised PY - 2019/08/19/accepted PY - 2019/8/25/entrez KW - ascites KW - ascites leak KW - blood patch KW - cirrhosis KW - complications KW - liver failure KW - paracentesis JF - Medical sciences (Basel, Switzerland) JO - Med Sci (Basel) VL - 7 IS - 9 N2 - Ascites, the fluid accumulation in the peritoneal cavity, is most commonly seen in patients with end-stage liver disease (ESLD). Evaluating ascites or providing symptomatic relief for patients is accomplished by performing a paracentesis. Ascites leak from a paracentesis site can be a complication of the procedure and is associated with increased morbidity. Currently, the best options for these patients include medical management or surgical abdominal wall layer closure. Utilizing a blood patch provides an alternative approach to managing such patients. A two-center prospective case series was performed evaluating the efficacy of the blood patch in patients with significant persistent ascites leak following a paracentesis. About 30 mL of the patients' peripheral blood was used for the blood patch. Subjects were recruited over a period of one year and followed for 30 days after the procedure. A total of six patients were recruited for this study. Subjects underwent placement of autologous blood patch at the site of the ascites leak and 100% had resolution of the leak within 24 hours. None of the subjects developed any complications of the procedure. This study shows that an autologous blood patch is an effective, low-risk treatment method for ascites leaks following a paracentesis. It is a simple bedside procedure that can reduce morbidity in patients with end-stage liver disease. SN - 2076-3271 UR - https://www.unboundmedicine.com/medline/citation/31443552/Autologous_Blood_Patch_for_Persistent_Ascites_Leak_from_Non-Closing_Paracentesis_Tracts DB - PRIME DP - Unbound Medicine ER -
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