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Malignant Acanthosis Nigricans: An Indicator of Internal Malignancy.
J Coll Physicians Surg Pak. 2019 Sep; 29(9):888-890.JC

Abstract

Acanthosis nigricans is a skin disease characterised by symmetric velvety hyperpigmented, verrucous plaques of the intertriginous surfaces of the axilla, neck, inframammary, and mucocutaneous regions. Malignant acanthosis nigricans is a paraneoplastic phenomenon most commonly associated with gastric adenocarcinoma. Tripe palms, florid cutaneous papillomatosis and oral involvement along with generalised acanthosis nigricans are the features which are highly suggestive of internal malignancy. This case report describes a rare case of a patient who presented with combination of malignant acanthosis nigricans, tripe palms, florid cutaneous papillomatosis and oral involvement associated with undifferentiated malignant neoplasm of hepatic bile ducts.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Rizwan M
Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi, Pakistan.
Iftikhar N
Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi, Pakistan.
Sarfraz T
Department of Pathology, Army Medical College, Rawalpindi, Pakistan.
Ullah O
Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi, Pakistan.

MeSH

Acanthosis NigricansBile Duct NeoplasmsBile Ducts, IntrahepaticCarcinomaHumansMaleMiddle Aged

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

31455489

Citation

Rizwan, Muhammad, et al. "Malignant Acanthosis Nigricans: an Indicator of Internal Malignancy." Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, vol. 29, no. 9, 2019, pp. 888-890.
Rizwan M, Iftikhar N, Sarfraz T, et al. Malignant Acanthosis Nigricans: An Indicator of Internal Malignancy. J Coll Physicians Surg Pak. 2019;29(9):888-890.
Rizwan, M., Iftikhar, N., Sarfraz, T., & Ullah, O. (2019). Malignant Acanthosis Nigricans: An Indicator of Internal Malignancy. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 29(9), 888-890. https://doi.org/10.29271/jcpsp.2019.09.888
Rizwan M, et al. Malignant Acanthosis Nigricans: an Indicator of Internal Malignancy. J Coll Physicians Surg Pak. 2019;29(9):888-890. PubMed PMID: 31455489.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Malignant Acanthosis Nigricans: An Indicator of Internal Malignancy. AU - Rizwan,Muhammad, AU - Iftikhar,Nadia, AU - Sarfraz,Tariq, AU - Ullah,Obed, PY - 2018/12/26/received PY - 2019/03/04/accepted PY - 2019/8/29/entrez PY - 2019/8/29/pubmed PY - 2020/2/7/medline SP - 888 EP - 890 JF - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP JO - J Coll Physicians Surg Pak VL - 29 IS - 9 N2 - Acanthosis nigricans is a skin disease characterised by symmetric velvety hyperpigmented, verrucous plaques of the intertriginous surfaces of the axilla, neck, inframammary, and mucocutaneous regions. Malignant acanthosis nigricans is a paraneoplastic phenomenon most commonly associated with gastric adenocarcinoma. Tripe palms, florid cutaneous papillomatosis and oral involvement along with generalised acanthosis nigricans are the features which are highly suggestive of internal malignancy. This case report describes a rare case of a patient who presented with combination of malignant acanthosis nigricans, tripe palms, florid cutaneous papillomatosis and oral involvement associated with undifferentiated malignant neoplasm of hepatic bile ducts. SN - 1681-7168 UR - https://www.unboundmedicine.com/medline/citation/31455489/Malignant_Acanthosis_Nigricans:_An_Indicator_of_Internal_Malignancy_ DB - PRIME DP - Unbound Medicine ER -