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[Rhinoviruses].
Internist (Berl). 2019 Nov; 60(11):1151-1154.I

Abstract

Human rhinoviruses (RV) belong to the Picornaviridae and are divided into three species: rhinovirus A, B and C. As causative viruses of upper airway infections (common cold), they possess enormous epidemiological and clinical importance. Furthermore, rhinoviruses are significant pathogens of acute exacerbations of chronic airway diseases such as asthma and chronic obstructive pulmonary disease. Their role as a cofactor in the development of pneumonia and their relevance in critically ill patients is still unclear and the focus of current research. Due to the unspecific clinical symptoms, diagnosis is difficult. Laboratory detection is sophisticated and a distinction between clinically relevant infection and contamination not always possible. Specific therapeutic antiviral strategies against rhinovirus infection do not exist as yet and, due to the large variety of subtypes, the development of vaccines remains a considerable challenge.

Authors+Show Affiliations

Pneumologie/Allergologie, Medizinische Klinik 1, Universitätsklinikum Frankfurt, Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.Pneumologie/Allergologie, Medizinische Klinik 1, Universitätsklinikum Frankfurt, Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.Pneumologie/Allergologie, Medizinische Klinik 1, Universitätsklinikum Frankfurt, Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland. gernot.rohde@kgu.de.

Pub Type(s)

Journal Article
Review

Language

ger

PubMed ID

31463521

Citation

Grünewaldt, A, et al. "[Rhinoviruses]." Der Internist, vol. 60, no. 11, 2019, pp. 1151-1154.
Grünewaldt A, Hügel C, Rohde GGU. [Rhinoviruses]. Internist (Berl). 2019;60(11):1151-1154.
Grünewaldt, A., Hügel, C., & Rohde, G. G. U. (2019). [Rhinoviruses]. Der Internist, 60(11), 1151-1154. https://doi.org/10.1007/s00108-019-00672-4
Grünewaldt A, Hügel C, Rohde GGU. [Rhinoviruses]. Internist (Berl). 2019;60(11):1151-1154. PubMed PMID: 31463521.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Rhinoviruses]. AU - Grünewaldt,A, AU - Hügel,C, AU - Rohde,G G U, PY - 2019/8/30/pubmed PY - 2019/11/7/medline PY - 2019/8/30/entrez KW - Antiviral agents KW - Disease exacerbation, viral KW - Picornaviridae KW - Pneumonia KW - Respiratory tract infection SP - 1151 EP - 1154 JF - Der Internist JO - Internist (Berl) VL - 60 IS - 11 N2 - Human rhinoviruses (RV) belong to the Picornaviridae and are divided into three species: rhinovirus A, B and C. As causative viruses of upper airway infections (common cold), they possess enormous epidemiological and clinical importance. Furthermore, rhinoviruses are significant pathogens of acute exacerbations of chronic airway diseases such as asthma and chronic obstructive pulmonary disease. Their role as a cofactor in the development of pneumonia and their relevance in critically ill patients is still unclear and the focus of current research. Due to the unspecific clinical symptoms, diagnosis is difficult. Laboratory detection is sophisticated and a distinction between clinically relevant infection and contamination not always possible. Specific therapeutic antiviral strategies against rhinovirus infection do not exist as yet and, due to the large variety of subtypes, the development of vaccines remains a considerable challenge. SN - 1432-1289 UR - https://www.unboundmedicine.com/medline/citation/31463521/[Rhinoviruses]_ L2 - https://dx.doi.org/10.1007/s00108-019-00672-4 DB - PRIME DP - Unbound Medicine ER -