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Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent.
Indian J Crit Care Med 2019; 23(8):352-355IJ

Abstract

Background and aims

Acute kidney injury (AKI) became an important cause of mortality and morbidity in critically ill children, despite advancement in its management. In developing countries etiology of AKI are different from that of developed countries.

Materials and methods

This observational study was carried out in pediatric intensive care unit (PICU) in 2 months to18 years of critically ill children. Kidney injury was defined and categorized by the pRIFLE criteria.

Results

Out of 361children, 86 children (23.8%) developed AKI at some point during admission, 275 children (age and sex matched) who did not develop kidney injury during hospitalization served as non-AKI children. Maximum cases of AKI were seen in 1-5 years of age. Maximum children of AKI were of viral encephalitis (n = 43, 50.0%) followed by scrub typhus (n = 14, 16.3%). Risk factors for the development of AKI were shock, PRISM score and longer hospital stay. In our study the mortality in AKI children (n = 30, 34.8%) was significantly higher (p = 0.005) as compared to non-AKI children (n = 56, 20.3%)). Duration on mechanical ventilation, PICU stay and hospital stay were also significantly (p = 0.001) higher in AKI children.

Conclusion

AKI is common in critically ill children and associated with high mortality and morbidity.

How to cite this article

Bharat A, Mehta A, Tiwari HC, Sharma B, Singh A, Singh V. Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent. Indian J Crit Care Med 2019;23(8):352-355.

Authors+Show Affiliations

Department of Pediatrics, Christian Medical College, Vellore, Tamil Nadu, India.Department of Pediatrics, BRD Medical College, Gorakhpur, Uttar Pradesh, India.Department of SPM, BRD Medical College, Gorakhpur, Uttar Pradesh, India.Department of Pediatrics, BRD Medical College, Gorakhpur, Uttar Pradesh, India.Department of Pediatrics, BRD Medical College, Gorakhpur, Uttar Pradesh, India.Department of Pediatrics, BRD Medical College, Gorakhpur, Uttar Pradesh, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31485103

Citation

Bharat, Ashwini, et al. "Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: a Snapshot Study From Indian Subcontinent." Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine, vol. 23, no. 8, 2019, pp. 352-355.
Bharat A, Mehta A, Tiwari HC, et al. Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent. Indian J Crit Care Med. 2019;23(8):352-355.
Bharat, A., Mehta, A., Tiwari, H. C., Sharma, B., Singh, A., & Singh, V. (2019). Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent. Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine, 23(8), pp. 352-355. doi:10.5005/jp-journals-10071-23217.
Bharat A, et al. Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: a Snapshot Study From Indian Subcontinent. Indian J Crit Care Med. 2019;23(8):352-355. PubMed PMID: 31485103.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent. AU - Bharat,Ashwini, AU - Mehta,Anita, AU - Tiwari,Harish Chandra, AU - Sharma,Bhupendra, AU - Singh,Abhishek, AU - Singh,Vijay, PY - 2019/9/6/entrez PY - 2019/9/6/pubmed PY - 2019/9/6/medline KW - Acute kidney injury (AKI) KW - Pediatric intensive care unit (PICU) KW - Scrub typhus KW - Viral encephalitis KW - pRIFLE SP - 352 EP - 355 JF - Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine JO - Indian J Crit Care Med VL - 23 IS - 8 N2 - Background and aims: Acute kidney injury (AKI) became an important cause of mortality and morbidity in critically ill children, despite advancement in its management. In developing countries etiology of AKI are different from that of developed countries. Materials and methods: This observational study was carried out in pediatric intensive care unit (PICU) in 2 months to18 years of critically ill children. Kidney injury was defined and categorized by the pRIFLE criteria. Results: Out of 361children, 86 children (23.8%) developed AKI at some point during admission, 275 children (age and sex matched) who did not develop kidney injury during hospitalization served as non-AKI children. Maximum cases of AKI were seen in 1-5 years of age. Maximum children of AKI were of viral encephalitis (n = 43, 50.0%) followed by scrub typhus (n = 14, 16.3%). Risk factors for the development of AKI were shock, PRISM score and longer hospital stay. In our study the mortality in AKI children (n = 30, 34.8%) was significantly higher (p = 0.005) as compared to non-AKI children (n = 56, 20.3%)). Duration on mechanical ventilation, PICU stay and hospital stay were also significantly (p = 0.001) higher in AKI children. Conclusion: AKI is common in critically ill children and associated with high mortality and morbidity. How to cite this article: Bharat A, Mehta A, Tiwari HC, Sharma B, Singh A, Singh V. Spectrum and Immediate Outcome of Acute Kidney Injury in a Pediatric Intensive Care Unit: A Snapshot Study from Indian Subcontinent. Indian J Crit Care Med 2019;23(8):352-355. SN - 0972-5229 UR - https://www.unboundmedicine.com/medline/citation/31485103/Spectrum_and_Immediate_Outcome_of_Acute_Kidney_Injury_in_a_Pediatric_Intensive_Care_Unit:_A_Snapshot_Study_from_Indian_Subcontinent L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/31485103/ DB - PRIME DP - Unbound Medicine ER -