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Reduced urinary opioid levels from pain management patients associated with marijuana use.
Pain Manag 2019; 9(5):441-447PM

Abstract

Aim:

Marijuana use has been postulated to modulate opioid use, dependence and withdrawal. Broad target drug testing results provide a unique perspective to identify any potential interaction between marijuana use and opioid use. Materials & methods: Using a dataset of approximately 800,000 urine drug test results collected from pain management patients of a time from of multiple years, creatinine corrected opioid levels were evaluated to determine if the presence of the primary marijuana marker 11-nor-carboxy-tetrahydrocannabinol (THC-COOH) was associated with statistical differences in excreted opioid concentrations. Results & conclusion: For each of the opioids investigated (codeine, morphine, hydrocodone, hydromorphone, oxycodone, oxymorphone, fentanyl and buprenorphine), marijuana use was associated with statistically significant lower urinary opiate levels than in samples without indicators of marijuana use.

Authors+Show Affiliations

MedTox Laboratories, Laboratory Corporation of America Holdings, St Paul, MN 55112, USA.MedTox Laboratories, Laboratory Corporation of America Holdings, St Paul, MN 55112, USA.Wilmington, NC, USA.MedTox Laboratories, Laboratory Corporation of America Holdings, St Paul, MN 55112, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31496363

Citation

Goggin, Melissa M., et al. "Reduced Urinary Opioid Levels From Pain Management Patients Associated With Marijuana Use." Pain Management, vol. 9, no. 5, 2019, pp. 441-447.
Goggin MM, Shahriar BJ, Stead A, et al. Reduced urinary opioid levels from pain management patients associated with marijuana use. Pain Manag. 2019;9(5):441-447.
Goggin, M. M., Shahriar, B. J., Stead, A., & Janis, G. C. (2019). Reduced urinary opioid levels from pain management patients associated with marijuana use. Pain Management, 9(5), pp. 441-447. doi:10.2217/pmt-2019-0017.
Goggin MM, et al. Reduced Urinary Opioid Levels From Pain Management Patients Associated With Marijuana Use. Pain Manag. 2019;9(5):441-447. PubMed PMID: 31496363.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reduced urinary opioid levels from pain management patients associated with marijuana use. AU - Goggin,Melissa M, AU - Shahriar,Breane J, AU - Stead,Andy, AU - Janis,Gregory C, Y1 - 2019/09/09/ PY - 2019/9/10/pubmed PY - 2019/9/10/medline PY - 2019/9/10/entrez KW - marijuana KW - opioids KW - pain management SP - 441 EP - 447 JF - Pain management JO - Pain Manag VL - 9 IS - 5 N2 - Aim: Marijuana use has been postulated to modulate opioid use, dependence and withdrawal. Broad target drug testing results provide a unique perspective to identify any potential interaction between marijuana use and opioid use. Materials & methods: Using a dataset of approximately 800,000 urine drug test results collected from pain management patients of a time from of multiple years, creatinine corrected opioid levels were evaluated to determine if the presence of the primary marijuana marker 11-nor-carboxy-tetrahydrocannabinol (THC-COOH) was associated with statistical differences in excreted opioid concentrations. Results & conclusion: For each of the opioids investigated (codeine, morphine, hydrocodone, hydromorphone, oxycodone, oxymorphone, fentanyl and buprenorphine), marijuana use was associated with statistically significant lower urinary opiate levels than in samples without indicators of marijuana use. SN - 1758-1877 UR - https://www.unboundmedicine.com/medline/citation/31496363/Reduced_urinary_opioid_levels_from_pain_management_patients_associated_with_marijuana_use L2 - http://www.futuremedicine.com/doi/full/10.2217/pmt-2019-0017?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -