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Oral histoplasmosis masquerading as acute necrotizing ulcerative gingivitis: A rare case report.
Int J Health Sci (Qassim). 2019 Sep-Oct; 13(5):37-40.IJ

Abstract

Histoplasmosis also called as "Darling's Disease" is a community-acquired primary pulmonary disease caused by inhalation of dust containing spores of soil-dwelling dimorphic fungi, Histoplasma capsulatum. Presentation of fungi in the oral cavity is usually rare and is generally associated with an immunocompromised state. Here, we present a rare case of histoplasmosis in an immunocompetent patient, with discrete oral presentation, that initially mimicked acute necrotizing ulcerative gingivitis. Gingival biopsy confirmed the diagnosis of histoplasmosis, which responded favorably to the initial treatment with intravenous amphotericin and later to oral itraconazole. Thus, a vigilant approach is paramount in reducing the fatality due to disease.

Authors+Show Affiliations

Department of Periodontology, Government College of Dentistry, Indore, Madhya Pradesh, India.Department of Periodontology, College of Dental Science and Hospital, Rau, Indore Madhya Pradesh, India.Department of Skin, VD and Leprosy, Maharaja Yashwantrao Hospital, Indore, Madhya Pradesh, India.Department of Oral Medicine, Diagnosis and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

31501651

Citation

Khetarpal, Shaleen, et al. "Oral Histoplasmosis Masquerading as Acute Necrotizing Ulcerative Gingivitis: a Rare Case Report." International Journal of Health Sciences, vol. 13, no. 5, 2019, pp. 37-40.
Khetarpal S, Mhapsekar T, Nagar R, et al. Oral histoplasmosis masquerading as acute necrotizing ulcerative gingivitis: A rare case report. Int J Health Sci (Qassim). 2019;13(5):37-40.
Khetarpal, S., Mhapsekar, T., Nagar, R., & Parihar, A. (2019). Oral histoplasmosis masquerading as acute necrotizing ulcerative gingivitis: A rare case report. International Journal of Health Sciences, 13(5), 37-40.
Khetarpal S, et al. Oral Histoplasmosis Masquerading as Acute Necrotizing Ulcerative Gingivitis: a Rare Case Report. Int J Health Sci (Qassim). 2019 Sep-Oct;13(5):37-40. PubMed PMID: 31501651.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oral histoplasmosis masquerading as acute necrotizing ulcerative gingivitis: A rare case report. AU - Khetarpal,Shaleen, AU - Mhapsekar,Trishna, AU - Nagar,Rahul, AU - Parihar,Ajay, PY - 2019/9/11/entrez PY - 2019/9/11/pubmed PY - 2019/9/11/medline KW - Darling’s disease KW - Oral histoplasmosis KW - acute necrotizing ulcerative gingivitis KW - immunocompetent SP - 37 EP - 40 JF - International journal of health sciences JO - Int J Health Sci (Qassim) VL - 13 IS - 5 N2 - Histoplasmosis also called as "Darling's Disease" is a community-acquired primary pulmonary disease caused by inhalation of dust containing spores of soil-dwelling dimorphic fungi, Histoplasma capsulatum. Presentation of fungi in the oral cavity is usually rare and is generally associated with an immunocompromised state. Here, we present a rare case of histoplasmosis in an immunocompetent patient, with discrete oral presentation, that initially mimicked acute necrotizing ulcerative gingivitis. Gingival biopsy confirmed the diagnosis of histoplasmosis, which responded favorably to the initial treatment with intravenous amphotericin and later to oral itraconazole. Thus, a vigilant approach is paramount in reducing the fatality due to disease. SN - 1658-3639 UR - https://www.unboundmedicine.com/medline/citation/31501651/Oral_histoplasmosis_masquerading_as_acute_necrotizing_ulcerative_gingivitis:_A_rare_case_report L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/31501651/ DB - PRIME DP - Unbound Medicine ER -
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