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Identification and phylogenetic analysis of an orf virus strain isolated in Anhui Province, East-central China, in 2018.
Acta Virol 2019; 63(3):270-277AV

Abstract

Orf, also called contagious ecthyma or contagious pustular dermatitis, is a significant zoonotic disease that primarily affects goat and sheep globally. Currently, the infection by orf virus (ORFV) has been observed in different host species worldwide, including China. Here, a suspected outbreak of orf infection in a goat farm in Anhui Province in 2018 was investigated. Through PCR, electron microscopy, and cell culture techniques, we confirmed that the outbreak was caused by ORFV. Consequently, the orf virus strain was named the AH/LA/2018 strain. The amplified and sequenced ORFV011 (B2L) and ORFV059 (F1L) genes were used to construct phylogenetic trees to elucidate the genetic characteristics of the ORFV and the molecular epidemiology of orf. The present study is the first systematic evolution analysis of the ORFV strain isolated in Anhui Province. The results of this study will be helpful to better understand the characteristics of ORFV, to help prevent and control the transmission of ORFV at an early stage in China. Keywords: Anhui Province; goat; orf virus; phylogenetic analysis.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

31507192

Citation

Wang, Y, et al. "Identification and Phylogenetic Analysis of an Orf Virus Strain Isolated in Anhui Province, East-central China, in 2018." Acta Virologica, vol. 63, no. 3, 2019, pp. 270-277.
Wang Y, Yang K, Wang YA, et al. Identification and phylogenetic analysis of an orf virus strain isolated in Anhui Province, East-central China, in 2018. Acta Virol. 2019;63(3):270-277.
Wang, Y., Yang, K., Wang, Y. A., Yu, Z., Zhang, Q., Zhang, G., ... Li, Y. (2019). Identification and phylogenetic analysis of an orf virus strain isolated in Anhui Province, East-central China, in 2018. Acta Virologica, 63(3), pp. 270-277. doi:10.4149/av_2019_304.
Wang Y, et al. Identification and Phylogenetic Analysis of an Orf Virus Strain Isolated in Anhui Province, East-central China, in 2018. Acta Virol. 2019;63(3):270-277. PubMed PMID: 31507192.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Identification and phylogenetic analysis of an orf virus strain isolated in Anhui Province, East-central China, in 2018. AU - Wang,Y, AU - Yang,K, AU - Wang,Y A, AU - Yu,Z, AU - Zhang,Q, AU - Zhang,G, AU - Su,L, AU - Lu,Z, AU - Zhang,X, AU - Liu,Z, AU - Jiang,S, AU - Li,Y, PY - 2019/9/12/entrez PY - 2019/9/12/pubmed PY - 2019/9/12/medline SP - 270 EP - 277 JF - Acta virologica JO - Acta Virol. VL - 63 IS - 3 N2 - Orf, also called contagious ecthyma or contagious pustular dermatitis, is a significant zoonotic disease that primarily affects goat and sheep globally. Currently, the infection by orf virus (ORFV) has been observed in different host species worldwide, including China. Here, a suspected outbreak of orf infection in a goat farm in Anhui Province in 2018 was investigated. Through PCR, electron microscopy, and cell culture techniques, we confirmed that the outbreak was caused by ORFV. Consequently, the orf virus strain was named the AH/LA/2018 strain. The amplified and sequenced ORFV011 (B2L) and ORFV059 (F1L) genes were used to construct phylogenetic trees to elucidate the genetic characteristics of the ORFV and the molecular epidemiology of orf. The present study is the first systematic evolution analysis of the ORFV strain isolated in Anhui Province. The results of this study will be helpful to better understand the characteristics of ORFV, to help prevent and control the transmission of ORFV at an early stage in China. Keywords: Anhui Province; goat; orf virus; phylogenetic analysis. SN - 0001-723X UR - https://www.unboundmedicine.com/medline/citation/31507192/Identification_and_phylogenetic_analysis_of_an_orf_virus_strain_isolated_in_Anhui_Province_East_central_China_in_2018_ L2 - http://www.aepress.sk/_downloads/dl.php?from=pubmed&journal=AV&file=2019_03_270.pdf DB - PRIME DP - Unbound Medicine ER -