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Recommendations for the treatment of schizophrenia with negative symptoms. Standards of pharmacotherapy by the Polish Psychiatric Association (Polskie Towarzystwo Psychiatryczne), part 1.
Psychiatr Pol 2019; 53(3):497-524PP

Abstract

Schizophrenia is a chronic illness that in the majority of cases begins either in adolescence or early adulthood. It is often perceived as a severe, incurable condition with generally poor prognosis, while patients suffering from it tend to be agitated, aggressive and unpredictable in their behaviors. Growing awareness, along with gradual changes in the approach to the need for multifaceted schizophrenia therapy, as well as considerable progress in pharmacotherapy in recent years have allowed for improving the prognosis for many patients. Because of polymorphic character of the condition, many schizophrenia sub-types are identified by means of classifications of mental disorders, adjusting the criteria and descriptions to most frequently observed clinical scenarios. Clinical descriptions of schizophrenia are based on various psychopathological models, which are often multidimensional and multifactorial. They virtually always take account of the following two dimensions: negative (deficit) and positive (creative) symptoms. Contemporary approach to schizophrenia treatment assumes multidirectional therapeutic intervention aimed at achieving full remission and the patient's return to full psychosocial functioning. Long-term studies indicate that the severity of negative symptoms is the prognostic indicator of the deterioration of social and professional functioning and reduced quality of life. The following paper presents the review of concepts and research devoted to negative symptoms in schizophrenia and their treatment; in the second part, international standards and recommendations of the Polish Psychiatric Association concerning the approach to effective management of negative symptoms in schizophrenia are discussed.

Authors+Show Affiliations

Warszawski Uniwersytet Medyczny, Wydział Nauki o Zdrowiu, Klinika Psychiatryczna.Pomorski Uniwersytet Medyczny w Szczecinie, Katedra i Klinika Psychiatrii.Uniwersytet Medyczny w Łodzi, Klinika Psychiatrii Dorosłych.Warszawski Uniwersytet Medyczny, Katedra i Klinika Psychiatryczna.Instytut Psychiatrii i Neurologii, Klinika Psychiatrii Sądowej.Uniwersytet Jagielloński Collegium Medicum, Klinika Psychiatrii Dorosłych.

Pub Type(s)

Guideline

Language

eng pol

PubMed ID

31522193

Citation

Szulc, Agata, et al. "Recommendations for the Treatment of Schizophrenia With Negative Symptoms. Standards of Pharmacotherapy By the Polish Psychiatric Association (Polskie Towarzystwo Psychiatryczne), Part 1." Psychiatria Polska, vol. 53, no. 3, 2019, pp. 497-524.
Szulc A, Samochowiec J, Gałecki P, et al. Recommendations for the treatment of schizophrenia with negative symptoms. Standards of pharmacotherapy by the Polish Psychiatric Association (Polskie Towarzystwo Psychiatryczne), part 1. Psychiatr Pol. 2019;53(3):497-524.
Szulc, A., Samochowiec, J., Gałecki, P., Wojnar, M., Heitzman, J., & Dudek, D. (2019). Recommendations for the treatment of schizophrenia with negative symptoms. Standards of pharmacotherapy by the Polish Psychiatric Association (Polskie Towarzystwo Psychiatryczne), part 1. Psychiatria Polska, 53(3), pp. 497-524. doi:10.12740/PP/OnlineFirst/100698.
Szulc A, et al. Recommendations for the Treatment of Schizophrenia With Negative Symptoms. Standards of Pharmacotherapy By the Polish Psychiatric Association (Polskie Towarzystwo Psychiatryczne), Part 1. Psychiatr Pol. 2019 Jun 30;53(3):497-524. PubMed PMID: 31522193.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recommendations for the treatment of schizophrenia with negative symptoms. Standards of pharmacotherapy by the Polish Psychiatric Association (Polskie Towarzystwo Psychiatryczne), part 1. AU - Szulc,Agata, AU - Samochowiec,Jerzy, AU - Gałecki,Piotr, AU - Wojnar,Marcin, AU - Heitzman,Janusz, AU - Dudek,Dominika, Y1 - 2019/06/30/ PY - 2019/9/16/entrez PY - 2019/9/16/pubmed PY - 2019/9/16/medline KW - negative symptoms KW - schizophrenia KW - treatment of schizophrenia SP - 497 EP - 524 JF - Psychiatria polska JO - Psychiatr. Pol. VL - 53 IS - 3 N2 - Schizophrenia is a chronic illness that in the majority of cases begins either in adolescence or early adulthood. It is often perceived as a severe, incurable condition with generally poor prognosis, while patients suffering from it tend to be agitated, aggressive and unpredictable in their behaviors. Growing awareness, along with gradual changes in the approach to the need for multifaceted schizophrenia therapy, as well as considerable progress in pharmacotherapy in recent years have allowed for improving the prognosis for many patients. Because of polymorphic character of the condition, many schizophrenia sub-types are identified by means of classifications of mental disorders, adjusting the criteria and descriptions to most frequently observed clinical scenarios. Clinical descriptions of schizophrenia are based on various psychopathological models, which are often multidimensional and multifactorial. They virtually always take account of the following two dimensions: negative (deficit) and positive (creative) symptoms. Contemporary approach to schizophrenia treatment assumes multidirectional therapeutic intervention aimed at achieving full remission and the patient's return to full psychosocial functioning. Long-term studies indicate that the severity of negative symptoms is the prognostic indicator of the deterioration of social and professional functioning and reduced quality of life. The following paper presents the review of concepts and research devoted to negative symptoms in schizophrenia and their treatment; in the second part, international standards and recommendations of the Polish Psychiatric Association concerning the approach to effective management of negative symptoms in schizophrenia are discussed. SN - 2391-5854 UR - https://www.unboundmedicine.com/medline/citation/31522193/Recommendations_for_the_treatment_of_schizophrenia_with_negative_symptoms._Standards_of_pharmacotherapy_by_the_Polish_Psychiatric_Association_(Polskie_Towarzystwo_Psychiatryczne),_part_1 L2 - https://doi.org/10.12740/PP/OnlineFirst/100698 DB - PRIME DP - Unbound Medicine ER -