Tags

Type your tag names separated by a space and hit enter

[Biliary microbiote in cholecystectomized patients: Review of empirical antibiotherapy].
Rev Esp Quimioter 2019; 32(5):426-431RE

Abstract

OBJECTIVE

Cholecystitis is an important cause of hospital admission. In moderate or severe cholecystitis, the delay in treatment can lead to serious complications. Our objective is to analyze the microorganisms isolated in bile from cholecystectomized patients and their sensitivity pattern, to evaluate the empirical treatment in those cases in which the surgical removal of the gallbladder should be delayed.

METHODS

Prospective descriptive study of biliary cultures of patients undergoing cholecystectomy from May 2013 to February 2015, in the Surgery Department of the Hospital General Universitari de Castelló.

RESULTS

We studied 196 patients, 83 women (42.3%) and 113 men (57.7%), with an average age of 61.5 years. The most used antibiotics as empiric treatment were piperacillin/tazobactam (77.8%) and amoxicillin/clavulanic (14.8%). In 46.4% of patients (91/196) bile cultures were positive. 165 microorganisms were isolated. The majority were Gram-negative bacilli (60.5%), mainly of the Enterobacterales order (91/54.5%), with Escherichia coli being the most frequent microorganism (24%) followed by Klebsiella spp. (12.5%). 3 E. coli with extended-spectrum beta-lactamase (ESBL) and 1 K. pneumoniae with ESBL were isolated. Microorganisms producing carbapenemase and methicillin-resistant Staphylococcus aureus were not isolated.

CONCLUSIONS

The bile microbiota, with a predominance of Enterobacterales is similar to that found in european studies..

Authors+Show Affiliations

María Gil Fortuño, Servicio de Microbiología y Parasitología. Hospital General Universitari de Castelló. Avenida de Benicàssim, sn. 12004, Castelló, Spain. gil_marfor@gva.es.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

31531672

Citation

Gil Fortuño, M, et al. "[Biliary Microbiote in Cholecystectomized Patients: Review of Empirical Antibiotherapy]." Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia, vol. 32, no. 5, 2019, pp. 426-431.
Gil Fortuño M, Granel Villach L, Sabater Vidal S, et al. [Biliary microbiote in cholecystectomized patients: Review of empirical antibiotherapy]. Rev Esp Quimioter. 2019;32(5):426-431.
Gil Fortuño, M., Granel Villach, L., Sabater Vidal, S., Soria Martín, R., Martínez Ramos, D., Escrig Sos, J., ... Igual Adell, R. (2019). [Biliary microbiote in cholecystectomized patients: Review of empirical antibiotherapy]. Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia, 32(5), pp. 426-431.
Gil Fortuño M, et al. [Biliary Microbiote in Cholecystectomized Patients: Review of Empirical Antibiotherapy]. Rev Esp Quimioter. 2019;32(5):426-431. PubMed PMID: 31531672.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Biliary microbiote in cholecystectomized patients: Review of empirical antibiotherapy]. AU - Gil Fortuño,M, AU - Granel Villach,L, AU - Sabater Vidal,S, AU - Soria Martín,R, AU - Martínez Ramos,D, AU - Escrig Sos,J, AU - Moreno Muñoz,R, AU - Igual Adell,R, Y1 - 2019/09/18/ PY - 2019/9/19/pubmed PY - 2019/9/19/medline PY - 2019/9/19/entrez SP - 426 EP - 431 JF - Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia JO - Rev Esp Quimioter VL - 32 IS - 5 N2 - OBJECTIVE: Cholecystitis is an important cause of hospital admission. In moderate or severe cholecystitis, the delay in treatment can lead to serious complications. Our objective is to analyze the microorganisms isolated in bile from cholecystectomized patients and their sensitivity pattern, to evaluate the empirical treatment in those cases in which the surgical removal of the gallbladder should be delayed. METHODS: Prospective descriptive study of biliary cultures of patients undergoing cholecystectomy from May 2013 to February 2015, in the Surgery Department of the Hospital General Universitari de Castelló. RESULTS: We studied 196 patients, 83 women (42.3%) and 113 men (57.7%), with an average age of 61.5 years. The most used antibiotics as empiric treatment were piperacillin/tazobactam (77.8%) and amoxicillin/clavulanic (14.8%). In 46.4% of patients (91/196) bile cultures were positive. 165 microorganisms were isolated. The majority were Gram-negative bacilli (60.5%), mainly of the Enterobacterales order (91/54.5%), with Escherichia coli being the most frequent microorganism (24%) followed by Klebsiella spp. (12.5%). 3 E. coli with extended-spectrum beta-lactamase (ESBL) and 1 K. pneumoniae with ESBL were isolated. Microorganisms producing carbapenemase and methicillin-resistant Staphylococcus aureus were not isolated. CONCLUSIONS: The bile microbiota, with a predominance of Enterobacterales is similar to that found in european studies.. SN - 1988-9518 UR - https://www.unboundmedicine.com/medline/citation/31531672/[Biliary_microbiote_in_cholecystectomized_patients:_Review_of_empirical_antibiotherapy] L2 - http://seq.es/abstract/september-18-2 DB - PRIME DP - Unbound Medicine ER -