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Combined deficiency of coagulation factors II, VII, IX, and X: a case of probable congenital origin.
Pediatr Hematol Oncol 1986; 3(2):187-93PH

Abstract

Combined deficiency of coagulant activity of the vitamin K-dependent factors was found in a 14-year-old boy suffering from severe hemorrhages. Immunoassays revealed the presence of acarboxyprothrombin. The bleedings could be controlled, but the coagulation defects persisted during more than 2 years' follow-up and could not be corrected by oral or parenteral vitamin K. No intoxication or underlying disease was found. The abnormality was considered a congenital disorder of the carboxylation of prothrombin.

Authors+Show Affiliations

Department of Paediatrics, Ostra Sjukhuset, Göteborg, Sweden.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Letter

Language

eng

PubMed ID

3153231

Citation

Ekelund, H, et al. "Combined Deficiency of Coagulation Factors II, VII, IX, and X: a Case of Probable Congenital Origin." Pediatric Hematology and Oncology, vol. 3, no. 2, 1986, pp. 187-93.
Ekelund H, Lindeberg L, Wranne L. Combined deficiency of coagulation factors II, VII, IX, and X: a case of probable congenital origin. Pediatr Hematol Oncol. 1986;3(2):187-93.
Ekelund, H., Lindeberg, L., & Wranne, L. (1986). Combined deficiency of coagulation factors II, VII, IX, and X: a case of probable congenital origin. Pediatric Hematology and Oncology, 3(2), pp. 187-93.
Ekelund H, Lindeberg L, Wranne L. Combined Deficiency of Coagulation Factors II, VII, IX, and X: a Case of Probable Congenital Origin. Pediatr Hematol Oncol. 1986;3(2):187-93. PubMed PMID: 3153231.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined deficiency of coagulation factors II, VII, IX, and X: a case of probable congenital origin. AU - Ekelund,H, AU - Lindeberg,L, AU - Wranne,L, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 187 EP - 93 JF - Pediatric hematology and oncology JO - Pediatr Hematol Oncol VL - 3 IS - 2 N2 - Combined deficiency of coagulant activity of the vitamin K-dependent factors was found in a 14-year-old boy suffering from severe hemorrhages. Immunoassays revealed the presence of acarboxyprothrombin. The bleedings could be controlled, but the coagulation defects persisted during more than 2 years' follow-up and could not be corrected by oral or parenteral vitamin K. No intoxication or underlying disease was found. The abnormality was considered a congenital disorder of the carboxylation of prothrombin. SN - 0888-0018 UR - https://www.unboundmedicine.com/medline/citation/3153231/Combined_deficiency_of_coagulation_factors_II_VII_IX_and_X:_a_case_of_probable_congenital_origin_ L2 - http://www.tandfonline.com/doi/full/10.3109/08880018609031217 DB - PRIME DP - Unbound Medicine ER -