Tags

Type your tag names separated by a space and hit enter

Dyspareunia Related to GSM: Association of Total Vaginal Thickness via Transabdominal Ultrasound.
J Sex Med. 2019 12; 16(12):2038-2042.JS

Abstract

INTRODUCTION

It has previously been suggested in the literature that ultrasound measurement of total vaginal wall thickness (TVT) differs significantly between pre- and postmenopausal women, indicating that it may be a useful and noninvasive objective assessment to correlate the degree of vaginal atrophy to patient-reported symptoms.

AIM

The purpose of this cross-sectional pilot study was to determine whether TVT in postmenopausal women, as measured with transabdominal ultrasound, is associated with patient-reported dyspareunia and symptoms related to genitourinary symptomatology.

METHODS

Postmenopausal women presenting for pelvic ultrasound had TVT and total mucosal thickness (TMT) measured via transabdominal ultrasound. A questionnaire also was administered assessing menopausal status, relevant medical history, and self-report of dyspareunia and other symptoms related to the genitourinary syndrome of menopause (GSM). This questionnaire was derived from the Vulvovaginal Symptom Questionnaire, which has been validated in the literature.

MAIN OUTCOME MEASURE

The main outcome measures included the average TVT and TMT for postmenopausal women reporting any symptom of GSM and average TVT and TMT of women reporting no symptoms of GSM.

RESULTS

Data from 44 postmenopausal women showed no significant association between transabdominal ultrasound-measured TVT or TMT and patient report of dyspareunia or other genitourinary symptoms. Data were stratified by individual GSM symptoms, sexual symptoms as an aggregate, and individual sexual symptoms. Neither of these subgroups showed a statistically significant difference in TVT or TMT between symptomatic and asymptomatic women.

CLINICAL IMPLICATIONS

Although no statistically significant data were derived from this study, we propose that future studies investigating the longitudinal relationship between TVT and GSM symptomatology may show an association between total vaginal thickness measurement change over time as determined by ultrasound with the presence of patient-reported dyspareunia and other GSM symptoms.

STRENGTHS & LIMITATIONS

This study is limited by its small sample size as well as the patient population, which was restricted to postmenopausal women with a clinical indication for ultrasound. A major strength of this investigation is that it is the first study to look at the relationship between sexual pain and other GSM symptoms and TVT using transabdominal ultrasound, which is a readily available, non-invasive tool in most clinical settings.

CONCLUSION

Based on the results of this small pilot study, transabdominal pelvic ultrasound cannot be used at this time to objectively quantify the presence of sexual pain or other GSM symptoms; however, future studies should continue to investigate the longitudinal relationship between these 2 variables. Balica AC, Cooper AM, McKevitt MK, et al. Dyspareunia Related to GSM: Association of Total Vaginal Thickness via Transabdominal Ultrasound. J Sex Med 2019; 16:2038-2042.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Women's Health Institute, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ.Department of Obstetrics and Gynecology, Women's Health Institute, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ. Electronic address: alexandria.cooper@rutgers.edu.Department of Obstetrics and Gynecology, Women's Health Institute, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ.Department of Obstetrics and Gynecology, Women's Health Institute, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ.Department of Obstetrics and Gynecology, Emory University, Atlanta, GA.Department of Obstetrics and Gynecology, Women's Health Institute, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ.Department of Obstetrics and Gynecology, Women's Health Institute, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31542351

Citation

Balica, Adrian C., et al. "Dyspareunia Related to GSM: Association of Total Vaginal Thickness Via Transabdominal Ultrasound." The Journal of Sexual Medicine, vol. 16, no. 12, 2019, pp. 2038-2042.
Balica AC, Cooper AM, McKevitt MK, et al. Dyspareunia Related to GSM: Association of Total Vaginal Thickness via Transabdominal Ultrasound. J Sex Med. 2019;16(12):2038-2042.
Balica, A. C., Cooper, A. M., McKevitt, M. K., Schertz, K., Wald-Spielman, D., Egan, S., & Bachmann, G. A. (2019). Dyspareunia Related to GSM: Association of Total Vaginal Thickness via Transabdominal Ultrasound. The Journal of Sexual Medicine, 16(12), 2038-2042. https://doi.org/10.1016/j.jsxm.2019.08.019
Balica AC, et al. Dyspareunia Related to GSM: Association of Total Vaginal Thickness Via Transabdominal Ultrasound. J Sex Med. 2019;16(12):2038-2042. PubMed PMID: 31542351.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dyspareunia Related to GSM: Association of Total Vaginal Thickness via Transabdominal Ultrasound. AU - Balica,Adrian C, AU - Cooper,Alexandria M, AU - McKevitt,Mariah K, AU - Schertz,Katherine, AU - Wald-Spielman,Daniella, AU - Egan,Susan, AU - Bachmann,Gloria A, Y1 - 2019/09/18/ PY - 2019/03/22/received PY - 2019/08/13/revised PY - 2019/08/18/accepted PY - 2019/9/23/pubmed PY - 2020/7/9/medline PY - 2019/9/23/entrez KW - Genitourinary Syndrome of Menopause KW - Pelvic Ultrasound KW - Sexual Dysfunction KW - Total Vaginal Thickness KW - Vaginal Atrophy SP - 2038 EP - 2042 JF - The journal of sexual medicine JO - J Sex Med VL - 16 IS - 12 N2 - INTRODUCTION: It has previously been suggested in the literature that ultrasound measurement of total vaginal wall thickness (TVT) differs significantly between pre- and postmenopausal women, indicating that it may be a useful and noninvasive objective assessment to correlate the degree of vaginal atrophy to patient-reported symptoms. AIM: The purpose of this cross-sectional pilot study was to determine whether TVT in postmenopausal women, as measured with transabdominal ultrasound, is associated with patient-reported dyspareunia and symptoms related to genitourinary symptomatology. METHODS: Postmenopausal women presenting for pelvic ultrasound had TVT and total mucosal thickness (TMT) measured via transabdominal ultrasound. A questionnaire also was administered assessing menopausal status, relevant medical history, and self-report of dyspareunia and other symptoms related to the genitourinary syndrome of menopause (GSM). This questionnaire was derived from the Vulvovaginal Symptom Questionnaire, which has been validated in the literature. MAIN OUTCOME MEASURE: The main outcome measures included the average TVT and TMT for postmenopausal women reporting any symptom of GSM and average TVT and TMT of women reporting no symptoms of GSM. RESULTS: Data from 44 postmenopausal women showed no significant association between transabdominal ultrasound-measured TVT or TMT and patient report of dyspareunia or other genitourinary symptoms. Data were stratified by individual GSM symptoms, sexual symptoms as an aggregate, and individual sexual symptoms. Neither of these subgroups showed a statistically significant difference in TVT or TMT between symptomatic and asymptomatic women. CLINICAL IMPLICATIONS: Although no statistically significant data were derived from this study, we propose that future studies investigating the longitudinal relationship between TVT and GSM symptomatology may show an association between total vaginal thickness measurement change over time as determined by ultrasound with the presence of patient-reported dyspareunia and other GSM symptoms. STRENGTHS & LIMITATIONS: This study is limited by its small sample size as well as the patient population, which was restricted to postmenopausal women with a clinical indication for ultrasound. A major strength of this investigation is that it is the first study to look at the relationship between sexual pain and other GSM symptoms and TVT using transabdominal ultrasound, which is a readily available, non-invasive tool in most clinical settings. CONCLUSION: Based on the results of this small pilot study, transabdominal pelvic ultrasound cannot be used at this time to objectively quantify the presence of sexual pain or other GSM symptoms; however, future studies should continue to investigate the longitudinal relationship between these 2 variables. Balica AC, Cooper AM, McKevitt MK, et al. Dyspareunia Related to GSM: Association of Total Vaginal Thickness via Transabdominal Ultrasound. J Sex Med 2019; 16:2038-2042. SN - 1743-6109 UR - https://www.unboundmedicine.com/medline/citation/31542351/Dyspareunia_Related_to_GSM:_Association_of_Total_Vaginal_Thickness_via_Transabdominal_Ultrasound_ DB - PRIME DP - Unbound Medicine ER -