Tags

Type your tag names separated by a space and hit enter

Gastrointestinal Beriberi and Wernicke's Encephalopathy Triggered by One Session of Heavy Drinking.
Case Rep Neurol 2019 Jan-Apr; 11(1):124-131CR

Abstract

An otherwise healthy 30-year-old male acquired gastrointestinal beriberi and subsequent Wernicke's encephalopathy after 1 session of heavy drinking. Nausea, vomiting, and anorexia relentlessly progressed. The patient developed external ophthalmoplegia after 2 months. Intravenous 1,000 mg thiamine reversed both neurologic and gastrointestinal symptoms within hours. It is hard to diagnose gastrointestinal beriberi since the symptoms are nonspecific. The patient underwent 11 emergency room visits, 3 hospital admissions, and laparoscopic cystectomy within 2 months, but the gastrointestinal symptoms continued to progress. Two months after the onset of gastrointestinal symptoms, external ophthalmoplegia appeared, and, therefore, intravenous thiamine was given. The simultaneous resolution of the debilitating gastrointestinal symptoms and external ophthalmoplegia was unique. Thiamine deficiency remains underdiagnosed and should be considered in patients who develop unexplained gastroparesis or autonomic nervous failure of the digestive system, even in the nonalcoholic population.

Authors+Show Affiliations

A.T. Still University School of Osteopathic Medicine in Arizona, Mesa, Arizona, USA.Renown Institute for Neuroscience, Renown Health, Reno, Nevada, USA. Department of Neurology, University of Nevada, Reno, Nevada, USA.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

31543793

Citation

Tjong, Elysia, and Yen-Yi Peng. "Gastrointestinal Beriberi and Wernicke's Encephalopathy Triggered By One Session of Heavy Drinking." Case Reports in Neurology, vol. 11, no. 1, 2019, pp. 124-131.
Tjong E, Peng YY. Gastrointestinal Beriberi and Wernicke's Encephalopathy Triggered by One Session of Heavy Drinking. Case Rep Neurol. 2019;11(1):124-131.
Tjong, E., & Peng, Y. Y. (2019). Gastrointestinal Beriberi and Wernicke's Encephalopathy Triggered by One Session of Heavy Drinking. Case Reports in Neurology, 11(1), pp. 124-131. doi:10.1159/000499601.
Tjong E, Peng YY. Gastrointestinal Beriberi and Wernicke's Encephalopathy Triggered By One Session of Heavy Drinking. Case Rep Neurol. 2019;11(1):124-131. PubMed PMID: 31543793.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gastrointestinal Beriberi and Wernicke's Encephalopathy Triggered by One Session of Heavy Drinking. AU - Tjong,Elysia, AU - Peng,Yen-Yi, Y1 - 2019/04/18/ PY - 2019/02/15/received PY - 2019/03/09/accepted PY - 2019/9/24/entrez PY - 2019/9/24/pubmed PY - 2019/9/24/medline KW - Gastrointestinal beriberi KW - Thiamine KW - Wernicke's encephalopathy SP - 124 EP - 131 JF - Case reports in neurology JO - Case Rep Neurol VL - 11 IS - 1 N2 - An otherwise healthy 30-year-old male acquired gastrointestinal beriberi and subsequent Wernicke's encephalopathy after 1 session of heavy drinking. Nausea, vomiting, and anorexia relentlessly progressed. The patient developed external ophthalmoplegia after 2 months. Intravenous 1,000 mg thiamine reversed both neurologic and gastrointestinal symptoms within hours. It is hard to diagnose gastrointestinal beriberi since the symptoms are nonspecific. The patient underwent 11 emergency room visits, 3 hospital admissions, and laparoscopic cystectomy within 2 months, but the gastrointestinal symptoms continued to progress. Two months after the onset of gastrointestinal symptoms, external ophthalmoplegia appeared, and, therefore, intravenous thiamine was given. The simultaneous resolution of the debilitating gastrointestinal symptoms and external ophthalmoplegia was unique. Thiamine deficiency remains underdiagnosed and should be considered in patients who develop unexplained gastroparesis or autonomic nervous failure of the digestive system, even in the nonalcoholic population. SN - 1662-680X UR - https://www.unboundmedicine.com/medline/citation/31543793/Gastrointestinal_Beriberi_and_Wernicke's_Encephalopathy_Triggered_by_One_Session_of_Heavy_Drinking L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/31543793/ DB - PRIME DP - Unbound Medicine ER -