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Ovarian Teratoma presenting as Anti NMDAR Antibody Negative Limbic Encephalitis.
J Assoc Physicians India. 2019 Sep; 67(9):94-95.JA

Abstract

Anti NMDA receptor (NMDAR) antibody mediated limbic encephalitis is the most common type of autoimmune encephalitis. Nearly half of the females presenting with anti NMDAR encephalitis have associated ovarian teratoma. Almost all of them have positive anti NMDAR antibody. Here we present a case of ovarian teratoma associated limbic encephalitis, with clinical picture typical of anti NMDAR mediated encephalitis, who was found to be negative for the antiNMDAR antibody. Clinicians should not defer from investigating a case of suspected anti NMDAR encephalitis for ovarian teratoma, even if antibody is negative.

Authors+Show Affiliations

Thomas AG
Senior Resident.
Mohan M
Professor, Pushpagiri Institute Of Medical Sciences And Research Centre, Thiruvalla, Kerala.
Thomas R
Professor, Pushpagiri Institute Of Medical Sciences And Research Centre, Thiruvalla, Kerala.
Baby FM
Senior Resident.

MeSH

Anti-N-Methyl-D-Aspartate Receptor EncephalitisAutoantibodiesFemaleHumansLimbic EncephalitisOvarian NeoplasmsReceptors, N-Methyl-D-AspartateTeratoma

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

31561702

Citation

Thomas, Ancil George, et al. "Ovarian Teratoma Presenting as Anti NMDAR Antibody Negative Limbic Encephalitis." The Journal of the Association of Physicians of India, vol. 67, no. 9, 2019, pp. 94-95.
Thomas AG, Mohan M, Thomas R, et al. Ovarian Teratoma presenting as Anti NMDAR Antibody Negative Limbic Encephalitis. J Assoc Physicians India. 2019;67(9):94-95.
Thomas, A. G., Mohan, M., Thomas, R., & Baby, F. M. (2019). Ovarian Teratoma presenting as Anti NMDAR Antibody Negative Limbic Encephalitis. The Journal of the Association of Physicians of India, 67(9), 94-95.
Thomas AG, et al. Ovarian Teratoma Presenting as Anti NMDAR Antibody Negative Limbic Encephalitis. J Assoc Physicians India. 2019;67(9):94-95. PubMed PMID: 31561702.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ovarian Teratoma presenting as Anti NMDAR Antibody Negative Limbic Encephalitis. AU - Thomas,Ancil George, AU - Mohan,Madhusudanan, AU - Thomas,Reji, AU - Baby,Finu Mathew, PY - 2019/9/29/entrez PY - 2019/9/29/pubmed PY - 2019/10/9/medline SP - 94 EP - 95 JF - The Journal of the Association of Physicians of India JO - J Assoc Physicians India VL - 67 IS - 9 N2 - Anti NMDA receptor (NMDAR) antibody mediated limbic encephalitis is the most common type of autoimmune encephalitis. Nearly half of the females presenting with anti NMDAR encephalitis have associated ovarian teratoma. Almost all of them have positive anti NMDAR antibody. Here we present a case of ovarian teratoma associated limbic encephalitis, with clinical picture typical of anti NMDAR mediated encephalitis, who was found to be negative for the antiNMDAR antibody. Clinicians should not defer from investigating a case of suspected anti NMDAR encephalitis for ovarian teratoma, even if antibody is negative. SN - 0004-5772 UR - https://www.unboundmedicine.com/medline/citation/31561702/Ovarian_Teratoma_presenting_as_Anti_NMDAR_Antibody_Negative_Limbic_Encephalitis_ L2 - http://www.diseaseinfosearch.org/result/4244 DB - PRIME DP - Unbound Medicine ER -