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Varices: Esophageal, Gastric, and Rectal.
Clin Liver Dis. 2019 11; 23(4):625-642.CL

Abstract

Gastrointestinal varices are associated with cirrhosis and portal hypertension. Variceal hemorrhage is a substantial cause of morbidity and mortality, with esophageal and gastric varices the most common source and rectal varices a much less common cause of severe gastrointestinal bleeding. The goals of managing variceal hemorrhage are control of active bleeding and prevention of rebleeding. This article focuses on reviewing the current management strategies, including optimal medical, endoscopic, and angiographic interventions and their clinical outcomes to achieve these goals. Evidence based discussion is used with current references as much as possible.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Kovacs TOG
Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Ronald Reagan - UCLA Medical Center, Olive View-UCLA Medical Center, Sylmar, CA, USA. Electronic address: TKovacs@mednet.ucla.edu.
Jensen DM
Medicine-GI, VA Greater Los Angeles Healthcare System, Ronald Reagan - UCLA Medical Center, David Geffen School of Medicine at UCLA, CURE:DDRC, Room 318, Building 115, 11301 Wilshire Boulevard, Los Angeles, CA 90073-1003, USA; Human Studies Core and GI Hemostasis Research Unit, VA/CURE Digestive Disease Research Center, Los Angeles, CA, USA.

MeSH

Adrenergic beta-AntagonistsCyanoacrylatesEndoscopy, Digestive SystemEsophageal and Gastric VaricesFluid TherapyGastrointestinal AgentsGastrointestinal HemorrhageHemostasis, EndoscopicHumansHypertension, PortalLigationOctreotideProctoscopyRectumSclerotherapyVaricose Veins

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Review

Language

eng

PubMed ID

31563215

Citation

Kovacs, Thomas O G., and Dennis M. Jensen. "Varices: Esophageal, Gastric, and Rectal." Clinics in Liver Disease, vol. 23, no. 4, 2019, pp. 625-642.
Kovacs TOG, Jensen DM. Varices: Esophageal, Gastric, and Rectal. Clin Liver Dis. 2019;23(4):625-642.
Kovacs, T. O. G., & Jensen, D. M. (2019). Varices: Esophageal, Gastric, and Rectal. Clinics in Liver Disease, 23(4), 625-642. https://doi.org/10.1016/j.cld.2019.07.005
Kovacs TOG, Jensen DM. Varices: Esophageal, Gastric, and Rectal. Clin Liver Dis. 2019;23(4):625-642. PubMed PMID: 31563215.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Varices: Esophageal, Gastric, and Rectal. AU - Kovacs,Thomas O G, AU - Jensen,Dennis M, Y1 - 2019/08/30/ PY - 2019/9/30/entrez PY - 2019/9/30/pubmed PY - 2020/7/21/medline KW - Band ligation KW - Esophageal varices KW - Gastric varices KW - Hematochezia KW - Portal hypertension KW - Rectal varices KW - Sclerotherapy KW - UGI bleed SP - 625 EP - 642 JF - Clinics in liver disease JO - Clin Liver Dis VL - 23 IS - 4 N2 - Gastrointestinal varices are associated with cirrhosis and portal hypertension. Variceal hemorrhage is a substantial cause of morbidity and mortality, with esophageal and gastric varices the most common source and rectal varices a much less common cause of severe gastrointestinal bleeding. The goals of managing variceal hemorrhage are control of active bleeding and prevention of rebleeding. This article focuses on reviewing the current management strategies, including optimal medical, endoscopic, and angiographic interventions and their clinical outcomes to achieve these goals. Evidence based discussion is used with current references as much as possible. SN - 1557-8224 UR - https://www.unboundmedicine.com/medline/citation/31563215/Varices:_Esophageal_Gastric_and_Rectal_ DB - PRIME DP - Unbound Medicine ER -