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Population genetics of 24 Y-STR loci in Chinese Han population from Jilin Province, Northeast China.
Mol Genet Genomic Med. 2019 Nov; 7(11):e984.MG

Abstract

BACKGROUND

It is meaningful to expand the available population information on forensic medicine and to investigate the genetic characteristics of Han population from Jilin Province, Northeast China.

METHODS

In this study, we investigated the genetic characteristics of 24 Y-chromosomal short tandem repeat (STR) loci in 1,088 unrelated Chinese Han male individuals from Jilin Province, using DNATyper^TM Y24 amplification kit. Additionally, we performed the population comparison between the Jilin population and the other nine reported populations based on the Y-STR genotyping haplotypes.

RESULTS

A total of 1,067 different haplotypes were found from 1,088 unrelated individuals, of which 1,046 were unique and 21 were shared by two individuals. The gene diversity values of 22 loci ranged from 0.3870 (DYS391) to 0.9668 (DYS385ab). The random match probability was 0.0010 with the discrimination capacity of 0.9807. Population comparison showed that there were minor differences compared to Beijing Chinese Han, China Manchu, Gansu Chinese Han, and Jiangsu Chinese Han, but major differences with respect to the populations of Guangdong Chinese Han, Yunnan Chinese Han, China Hui, China Korean, and China Tibetan.

CONCLUSION

Our results showed that the 24 Y-STR loci in Jilin Han population are valuable for forensic application and human genetics.

Links

Authors+Show Affiliations

School of Forensic Medicine, China Medical University, Shenyang, China.

Department of Forensic Medicine, Criminal Investigation Police University of China, Shenyang, China.

School of Forensic Medicine, China Medical University, Shenyang, China.

School of Forensic Medicine, China Medical University, Shenyang, China.

School of Forensic Medicine, China Medical University, Shenyang, China.

School of Forensic Medicine, China Medical University, Shenyang, China.

MeSH

Asian PeopleChromosomes, Human, YEthnicityGenetics, PopulationHumansMaleMicrosatellite RepeatsPolymorphism, Genetic

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31566932

Citation

Xu, Xiao-Ming, et al. "Population Genetics of 24 Y-STR Loci in Chinese Han Population From Jilin Province, Northeast China." Molecular Genetics & Genomic Medicine, vol. 7, no. 11, 2019, pp. e984.

Xu XM, Zheng JL, Lou Y, et al. Population genetics of 24 Y-STR loci in Chinese Han population from Jilin Province, Northeast China. Mol Genet Genomic Med. 2019;7(11):e984.

Xu, X. M., Zheng, J. L., Lou, Y., Wei, X. H., Wang, B. J., & Yao, J. (2019). Population genetics of 24 Y-STR loci in Chinese Han population from Jilin Province, Northeast China. Molecular Genetics & Genomic Medicine, 7(11), e984. https://doi.org/10.1002/mgg3.984

Xu XM, et al. Population Genetics of 24 Y-STR Loci in Chinese Han Population From Jilin Province, Northeast China. Mol Genet Genomic Med. 2019;7(11):e984. PubMed PMID: 31566932.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Population genetics of 24 Y-STR loci in Chinese Han population from Jilin Province, Northeast China. AU - Xu,Xiao-Ming, AU - Zheng,Ji-Long, AU - Lou,Yin, AU - Wei,Xiao-Han, AU - Wang,Bao-Jie, AU - Yao,Jun, Y1 - 2019/09/30/ PY - 2019/6/26/received PY - 2019/8/27/revised PY - 2019/9/3/accepted PY - 2019/10/1/pubmed PY - 2020/7/1/medline PY - 2019/10/1/entrez KW - DNATyperTM Y24 kit KW - Han population KW - Y-STR KW - haplotype SP - e984 EP - e984 JF - Molecular genetics & genomic medicine JO - Mol Genet Genomic Med VL - 7 IS - 11 N2 - BACKGROUND: It is meaningful to expand the available population information on forensic medicine and to investigate the genetic characteristics of Han population from Jilin Province, Northeast China. METHODS: In this study, we investigated the genetic characteristics of 24 Y-chromosomal short tandem repeat (STR) loci in 1,088 unrelated Chinese Han male individuals from Jilin Province, using DNATyperTM Y24 amplification kit. Additionally, we performed the population comparison between the Jilin population and the other nine reported populations based on the Y-STR genotyping haplotypes. RESULTS: A total of 1,067 different haplotypes were found from 1,088 unrelated individuals, of which 1,046 were unique and 21 were shared by two individuals. The gene diversity values of 22 loci ranged from 0.3870 (DYS391) to 0.9668 (DYS385ab). The random match probability was 0.0010 with the discrimination capacity of 0.9807. Population comparison showed that there were minor differences compared to Beijing Chinese Han, China Manchu, Gansu Chinese Han, and Jiangsu Chinese Han, but major differences with respect to the populations of Guangdong Chinese Han, Yunnan Chinese Han, China Hui, China Korean, and China Tibetan. CONCLUSION: Our results showed that the 24 Y-STR loci in Jilin Han population are valuable for forensic application and human genetics. SN - 2324-9269 UR - https://www.unboundmedicine.com/medline/citation/31566932/Population_genetics_of_24_Y_STR_loci_in_Chinese_Han_population_from_Jilin_Province_Northeast_China_ DB - PRIME DP - Unbound Medicine ER -