Tags

Type your tag names separated by a space and hit enter

Alcoholic Korsakoff's syndrome: some unresolved issues concerning etiology, neuropathology, and cognitive deficits.
J Clin Exp Neuropsychol. 1985 Apr; 7(2):181-210.JC

Abstract

Recent neuropsychological and neuropathological investigations with long-term alcoholics suggest that the etiology and neuropathology of the Wernicke-Korsakoff syndrome are more complex than previously believed. While problem solving and visuoperceptual deficits seem to develop slowly during decades of alcoholism, the amnesic symptoms associated with Korsakoff's syndrome may appear acutely when severe malnutrition and alcoholism are combined. Furthermore, the report that alcoholic Korsakoff patients, like patients with Alzheimer's Disease, have endured a substantial neuronal loss in the nucleus basalis of Meynert has questioned the role of the medial diencephalon in the alcoholic patients' amnesic syndrome. Some initial demonstrations of similarities in the memory disorders of alcoholic Korsakoff and Alzheimer patients indicate that Korsakoff's syndrome may be more accurately characterized as a "basal forebrain" than as a "diencephalic" amnesia.

Authors

No affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

3157699

Citation

Butters, N. "Alcoholic Korsakoff's Syndrome: some Unresolved Issues Concerning Etiology, Neuropathology, and Cognitive Deficits." Journal of Clinical and Experimental Neuropsychology, vol. 7, no. 2, 1985, pp. 181-210.
Butters N. Alcoholic Korsakoff's syndrome: some unresolved issues concerning etiology, neuropathology, and cognitive deficits. J Clin Exp Neuropsychol. 1985;7(2):181-210.
Butters, N. (1985). Alcoholic Korsakoff's syndrome: some unresolved issues concerning etiology, neuropathology, and cognitive deficits. Journal of Clinical and Experimental Neuropsychology, 7(2), 181-210.
Butters N. Alcoholic Korsakoff's Syndrome: some Unresolved Issues Concerning Etiology, Neuropathology, and Cognitive Deficits. J Clin Exp Neuropsychol. 1985;7(2):181-210. PubMed PMID: 3157699.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcoholic Korsakoff's syndrome: some unresolved issues concerning etiology, neuropathology, and cognitive deficits. A1 - Butters,N, PY - 1985/4/1/pubmed PY - 2000/3/29/medline PY - 1985/4/1/entrez SP - 181 EP - 210 JF - Journal of clinical and experimental neuropsychology JO - J Clin Exp Neuropsychol VL - 7 IS - 2 N2 - Recent neuropsychological and neuropathological investigations with long-term alcoholics suggest that the etiology and neuropathology of the Wernicke-Korsakoff syndrome are more complex than previously believed. While problem solving and visuoperceptual deficits seem to develop slowly during decades of alcoholism, the amnesic symptoms associated with Korsakoff's syndrome may appear acutely when severe malnutrition and alcoholism are combined. Furthermore, the report that alcoholic Korsakoff patients, like patients with Alzheimer's Disease, have endured a substantial neuronal loss in the nucleus basalis of Meynert has questioned the role of the medial diencephalon in the alcoholic patients' amnesic syndrome. Some initial demonstrations of similarities in the memory disorders of alcoholic Korsakoff and Alzheimer patients indicate that Korsakoff's syndrome may be more accurately characterized as a "basal forebrain" than as a "diencephalic" amnesia. SN - 1380-3395 UR - https://www.unboundmedicine.com/medline/citation/3157699/Alcoholic_Korsakoff's_syndrome:_some_unresolved_issues_concerning_etiology_neuropathology_and_cognitive_deficits_ L2 - https://www.tandfonline.com/doi/full/10.1080/01688638508401252 DB - PRIME DP - Unbound Medicine ER -