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[Short-term efficacy of vaginal CO2 laser therapy as a treatment modality for genitourinary syndrome of menopause].
Orv Hetil. 2019 Oct; 160(41):1617-1622.OH

Abstract

Introduction: Genitourinary syndrome of menopause (GSM) affects up to 40-57% of postmenopausal women. Intravaginal microablative fractional CO2 laser is a new proposal for the management of GSM, although the evidence of safety and efficacy of the procedure appears to be insufficient. Aim: The aim of the study was to assess the efficacy of fractional CO2 laser for the treatment of GSM at the Department of Obstetrics and Gynecology of the University of Debrecen. Method: Postmenopausal women with symptoms of GSM underwent three sessions of microablative fractional rejuvenation CO2 laser therapy at 4-6 weeks intervals. Vaginal health index (VHI) scores were completed before each treatment and at 6 weeks follow-up as an objective measurement and visual analog scale was used to assess subjective complaints. Statistical analysis included Student's paired two-sampling t-test for the measure of statistical significance using the standard cutoff for significance p<0.05. Results: 51 women participated (mean age 57.0 ± 9.9 y). Average VHI score was 14.0 ± 4.9 before treatment, 15.0 ± 4.7 after the first session, 18.2 ± 4.6 after the second treatment and 19.5 ± 4.9 at follow-up. The improvement of VHI score was statistically significant between all sessions. Average VAS score was 15.6 ± 14.1 before treatment, 9.0 ± 10.8 after the first session, 5.9 ± 9.2 after the second treatment and 3.4 ± 7.5 at follow-up. The improvement of VAS score was statistically also significant between all sessions. Conclusions: Our study suggests that the fractional CO2 laser is an effective and safe treatment of symptoms associated with GSM. Orv Hetil. 2019; 160(41): 1617-1622.

Authors+Show Affiliations

Szülészeti és Nőgyógyászati Intézet, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.Szülészeti és Nőgyógyászati Intézet, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.Szülészeti és Nőgyógyászati Intézet, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.II. Szülészeti és Nőgyógyászati Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.Department of Obstetrics and Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery, Eastern Virginia Medical School Norfolk, VA, USA.

Pub Type(s)

Journal Article

Language

hun

PubMed ID

31587579

Citation

Kozma, Bence, et al. "[Short-term Efficacy of Vaginal CO2 Laser Therapy as a Treatment Modality for Genitourinary Syndrome of Menopause]." Orvosi Hetilap, vol. 160, no. 41, 2019, pp. 1617-1622.
Kozma B, Póka R, Sipos A, et al. [Short-term efficacy of vaginal CO2 laser therapy as a treatment modality for genitourinary syndrome of menopause]. Orv Hetil. 2019;160(41):1617-1622.
Kozma, B., Póka, R., Sipos, A., Ács, N., & Takács, P. (2019). [Short-term efficacy of vaginal CO2 laser therapy as a treatment modality for genitourinary syndrome of menopause]. Orvosi Hetilap, 160(41), 1617-1622. https://doi.org/10.1556/650.2019.31529
Kozma B, et al. [Short-term Efficacy of Vaginal CO2 Laser Therapy as a Treatment Modality for Genitourinary Syndrome of Menopause]. Orv Hetil. 2019;160(41):1617-1622. PubMed PMID: 31587579.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Short-term efficacy of vaginal CO2 laser therapy as a treatment modality for genitourinary syndrome of menopause]. AU - Kozma,Bence, AU - Póka,Róbert, AU - Sipos,Attila, AU - Ács,Nándor, AU - Takács,Péter, PY - 2019/10/8/entrez PY - 2019/10/8/pubmed PY - 2019/11/7/medline KW - genitourinary syndrome of menopause KW - hüvelyi lézerkezelés KW - menopausalis genitourinalis szindróma KW - vaginal health index KW - vaginal laser treatment KW - visual analog scale KW - vizuális analóg skála KW - ’vaginal health index’ SP - 1617 EP - 1622 JF - Orvosi hetilap JO - Orv Hetil VL - 160 IS - 41 N2 - Introduction: Genitourinary syndrome of menopause (GSM) affects up to 40-57% of postmenopausal women. Intravaginal microablative fractional CO2 laser is a new proposal for the management of GSM, although the evidence of safety and efficacy of the procedure appears to be insufficient. Aim: The aim of the study was to assess the efficacy of fractional CO2 laser for the treatment of GSM at the Department of Obstetrics and Gynecology of the University of Debrecen. Method: Postmenopausal women with symptoms of GSM underwent three sessions of microablative fractional rejuvenation CO2 laser therapy at 4-6 weeks intervals. Vaginal health index (VHI) scores were completed before each treatment and at 6 weeks follow-up as an objective measurement and visual analog scale was used to assess subjective complaints. Statistical analysis included Student's paired two-sampling t-test for the measure of statistical significance using the standard cutoff for significance p<0.05. Results: 51 women participated (mean age 57.0 ± 9.9 y). Average VHI score was 14.0 ± 4.9 before treatment, 15.0 ± 4.7 after the first session, 18.2 ± 4.6 after the second treatment and 19.5 ± 4.9 at follow-up. The improvement of VHI score was statistically significant between all sessions. Average VAS score was 15.6 ± 14.1 before treatment, 9.0 ± 10.8 after the first session, 5.9 ± 9.2 after the second treatment and 3.4 ± 7.5 at follow-up. The improvement of VAS score was statistically also significant between all sessions. Conclusions: Our study suggests that the fractional CO2 laser is an effective and safe treatment of symptoms associated with GSM. Orv Hetil. 2019; 160(41): 1617-1622. SN - 1788-6120 UR - https://www.unboundmedicine.com/medline/citation/31587579/[Short_term_efficacy_of_vaginal_CO2_laser_therapy_as_a_treatment_modality_for_genitourinary_syndrome_of_menopause]_ DB - PRIME DP - Unbound Medicine ER -