Tags

Type your tag names separated by a space and hit enter

Estimation of Acutely Ill Medical Patients at Venous Thromboembolism Risk Eligible for Extended Thromboprophylaxis Using APEX Criteria in US Hospitals.
Clin Appl Thromb Hemost. 2019 Jan-Dec; 25:1076029619880008.CA

Abstract

Major medical illnesses place patients at risk of venous thromboembolism (VTE). Some risk factors including age ≥75 years or history of cancer place them at increased risk of VTE that extends for at least 5 to 6 weeks following hospital admission. Betrixaban thromboprophylaxis is now approved in the United States for this indication. We estimated the annual number of acutely ill medical patients at extended risk of VTE discharged from US hospital. Major medical illnesses (stroke, respiratory failure/chronic obstructive pulmonary disease, heart failure, pneumonia, other infections, and rheumatologic disorders) and 2 common risk factors for extended VTE risk, namely, age ≥75 years and history of cancer (active or past) were examined in 2014 US hospital discharges using the first 3 discharge diagnosis codes in the National Inpatient Sample (database of acute-care hospital discharges from the US Agency for Health Care Quality and Research). In 2014, there were 20.8 million discharges with potentially at risk of nonsurgical-related VTE. Overall, 7.2 million (35%) discharges corresponded to major medical illness that warranted thromboprophylaxis according to 2012 American College of Chest Physicians (ACCP) guideline. Among them, 2.79 million were aged ≥75 years and 1.36 million had a history of cancer (aged 40-74 years). Overall, 3.48 million discharges were at extended risk of VTE. Many medical inpatients at risk of VTE according to 2012 ACCP guideline might benefit from the awareness of continuing risk and some of these patients might benefit from extended thromboprophylaxis, depending on the risk of bleeding and comorbidities.

Authors+Show Affiliations

Innovations thérapeutiques en Hémostase, INSERM UMRS 1140, Faculté de Pharmacie, Paris Descartes, France.Center for Outcomes Research, University of Massachusetts Medical School, Worcester, MA, USA.Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.Division of Cardiology, Duke University and Duke Clinical Research Institute, Durham, NC, USA.Division of Cardiovascular, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.Center for Outcomes Research, University of Massachusetts Medical School, Worcester, MA, USA.Department of Haematology, Guy's, King's and St. Thomas's School of Medicine, London, United Kingdom.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31588785

Citation

Martin, Anne-Céline, et al. "Estimation of Acutely Ill Medical Patients at Venous Thromboembolism Risk Eligible for Extended Thromboprophylaxis Using APEX Criteria in US Hospitals." Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, vol. 25, 2019, p. 1076029619880008.
Martin AC, Huang W, Goldhaber SZ, et al. Estimation of Acutely Ill Medical Patients at Venous Thromboembolism Risk Eligible for Extended Thromboprophylaxis Using APEX Criteria in US Hospitals. Clin Appl Thromb Hemost. 2019;25:1076029619880008.
Martin, A. C., Huang, W., Goldhaber, S. Z., Hull, R. D., Hernandez, A. F., Gibson, C. M., Anderson, F. A., & Cohen, A. T. (2019). Estimation of Acutely Ill Medical Patients at Venous Thromboembolism Risk Eligible for Extended Thromboprophylaxis Using APEX Criteria in US Hospitals. Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 25, 1076029619880008. https://doi.org/10.1177/1076029619880008
Martin AC, et al. Estimation of Acutely Ill Medical Patients at Venous Thromboembolism Risk Eligible for Extended Thromboprophylaxis Using APEX Criteria in US Hospitals. Clin Appl Thromb Hemost. 2019;25:1076029619880008. PubMed PMID: 31588785.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Estimation of Acutely Ill Medical Patients at Venous Thromboembolism Risk Eligible for Extended Thromboprophylaxis Using APEX Criteria in US Hospitals. AU - Martin,Anne-Céline, AU - Huang,Wei, AU - Goldhaber,Samuel Z, AU - Hull,Russell D, AU - Hernandez,Adrian F, AU - Gibson,Charles-Michael, AU - Anderson,Frederick A, AU - Cohen,Alexander T, PY - 2019/10/8/entrez PY - 2019/10/8/pubmed PY - 2019/10/8/medline KW - acute medical illness KW - epidemiology KW - extended thromboprophylaxis KW - risk factors KW - venous thromboembolism SP - 1076029619880008 EP - 1076029619880008 JF - Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis JO - Clin. Appl. Thromb. Hemost. VL - 25 N2 - Major medical illnesses place patients at risk of venous thromboembolism (VTE). Some risk factors including age ≥75 years or history of cancer place them at increased risk of VTE that extends for at least 5 to 6 weeks following hospital admission. Betrixaban thromboprophylaxis is now approved in the United States for this indication. We estimated the annual number of acutely ill medical patients at extended risk of VTE discharged from US hospital. Major medical illnesses (stroke, respiratory failure/chronic obstructive pulmonary disease, heart failure, pneumonia, other infections, and rheumatologic disorders) and 2 common risk factors for extended VTE risk, namely, age ≥75 years and history of cancer (active or past) were examined in 2014 US hospital discharges using the first 3 discharge diagnosis codes in the National Inpatient Sample (database of acute-care hospital discharges from the US Agency for Health Care Quality and Research). In 2014, there were 20.8 million discharges with potentially at risk of nonsurgical-related VTE. Overall, 7.2 million (35%) discharges corresponded to major medical illness that warranted thromboprophylaxis according to 2012 American College of Chest Physicians (ACCP) guideline. Among them, 2.79 million were aged ≥75 years and 1.36 million had a history of cancer (aged 40-74 years). Overall, 3.48 million discharges were at extended risk of VTE. Many medical inpatients at risk of VTE according to 2012 ACCP guideline might benefit from the awareness of continuing risk and some of these patients might benefit from extended thromboprophylaxis, depending on the risk of bleeding and comorbidities. SN - 1938-2723 UR - https://www.unboundmedicine.com/medline/citation/31588785/Estimation_of_Acutely_Ill_Medical_Patients_at_Venous_Thromboembolism_Risk_Eligible_for_Extended_Thromboprophylaxis_Using_APEX_Criteria_in_US_Hospitals L2 - http://journals.sagepub.com/doi/full/10.1177/1076029619880008?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.