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Trends of leprosy and multibacillary infection in the state of Georgia since the early 1900s.
PLoS Negl Trop Dis. 2019 10; 13(10):e0007713.PN

Abstract

Few investigations to date have analyzed the epidemiology of Hansen's disease (leprosy) in the United States, and in particular, if birth location is related to multibacillary versus paucibacillary leprosy. We collected data on 123 patients diagnosed with leprosy in Georgia from the National Hansen's Disease Program from 1923-January 2018. A logistic regression model was built to examine the relationship between country of origin (U.S.-born or immigrant) and the type of leprosy. While the model showed no significant relationship between country of origin and type of leprosy, being Asian or Pacific Islander was associated with a higher odds of multibacillary disease (aOR = 5.71; 95% CI: 1.25-26.29). Furthermore, since the early 1900s, we found an increasing trend of leprosy reports in Georgia among both domestic born and immigrant residents, despite the overall decrease in cases in the United States during the same time period. More research is therefore necessary to further evaluate risk for multibacillary leprosy in certain populations and to create targeted interventions and prevention strategies.

Authors+Show Affiliations

Hubert Department of Global Health, Emory University Rollins School of Public Health Atlanta, GA, United States of America.National Hansen's Disease Programs, Baton Rouge, LA, United States of America.National Hansen's Disease Programs, Baton Rouge, LA, United States of America.Georgia Department of Public Health, Atlanta, GA, United States of America.Hubert Department of Global Health, Emory University Rollins School of Public Health Atlanta, GA, United States of America.

Pub Type(s)

Historical Article
Journal Article

Language

eng

PubMed ID

31603913

Citation

McCormick, Carter D., et al. "Trends of Leprosy and Multibacillary Infection in the State of Georgia Since the Early 1900s." PLoS Neglected Tropical Diseases, vol. 13, no. 10, 2019, pp. e0007713.
McCormick CD, Lea J, Stryjewska BM, et al. Trends of leprosy and multibacillary infection in the state of Georgia since the early 1900s. PLoS Negl Trop Dis. 2019;13(10):e0007713.
McCormick, C. D., Lea, J., Stryjewska, B. M., Thompson, A., & Fairley, J. K. (2019). Trends of leprosy and multibacillary infection in the state of Georgia since the early 1900s. PLoS Neglected Tropical Diseases, 13(10), e0007713. https://doi.org/10.1371/journal.pntd.0007713
McCormick CD, et al. Trends of Leprosy and Multibacillary Infection in the State of Georgia Since the Early 1900s. PLoS Negl Trop Dis. 2019;13(10):e0007713. PubMed PMID: 31603913.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Trends of leprosy and multibacillary infection in the state of Georgia since the early 1900s. AU - McCormick,Carter D, AU - Lea,Jacqueline, AU - Stryjewska,Barbara M, AU - Thompson,Ashton, AU - Fairley,Jessica K, Y1 - 2019/10/11/ PY - 2019/01/31/received PY - 2019/08/15/accepted PY - 2019/10/23/revised PY - 2019/10/12/pubmed PY - 2019/10/12/medline PY - 2019/10/12/entrez SP - e0007713 EP - e0007713 JF - PLoS neglected tropical diseases JO - PLoS Negl Trop Dis VL - 13 IS - 10 N2 - Few investigations to date have analyzed the epidemiology of Hansen's disease (leprosy) in the United States, and in particular, if birth location is related to multibacillary versus paucibacillary leprosy. We collected data on 123 patients diagnosed with leprosy in Georgia from the National Hansen's Disease Program from 1923-January 2018. A logistic regression model was built to examine the relationship between country of origin (U.S.-born or immigrant) and the type of leprosy. While the model showed no significant relationship between country of origin and type of leprosy, being Asian or Pacific Islander was associated with a higher odds of multibacillary disease (aOR = 5.71; 95% CI: 1.25-26.29). Furthermore, since the early 1900s, we found an increasing trend of leprosy reports in Georgia among both domestic born and immigrant residents, despite the overall decrease in cases in the United States during the same time period. More research is therefore necessary to further evaluate risk for multibacillary leprosy in certain populations and to create targeted interventions and prevention strategies. SN - 1935-2735 UR - https://www.unboundmedicine.com/medline/citation/31603913/Trends_of_leprosy_and_multibacillary_infection_in_the_state_of_Georgia_since_the_early_1900s_ L2 - http://dx.plos.org/10.1371/journal.pntd.0007713 DB - PRIME DP - Unbound Medicine ER -