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Sex differences in nonmedical prescription tranquilizer and stimulant use trends among secondary school students in Argentina, Chile, and Uruguay.
Drug Alcohol Depend. 2019 12 01; 205:107607.DA

Abstract

BACKGROUND

Little is known about recent nonmedical prescription tranquilizer and stimulant use trends in Latin America. We tested whether recent trends among students in three South American countries differed by sex over time.

METHODS

Three countries independently collected National School Students Survey on Drugs. Students in 8th, 10th, and 12th grades were sampled in Argentina (2007-2014, N = 328,202), Chile (2007-2015, N = 136,379), and Uruguay (2007-2016, N = 32,371). Weighted linear regression models predicted the prevalences and trends over time of past-year nonmedical tranquilizer and stimulant use by country, and tested whether trends differed by sex, adjusting for school type and grade.

RESULTS

In Argentina from 2007 to 2014, past-year nonmedical prescription tranquilizer (girls: 2.8 to 2.6%, boys: 2.5 to 2.3%) and stimulant (girls: 1.7 to 1.3%, boys: 1.9 to 1.5%) use trends did not differ by sex. In Chile from 2007 to 2015, nonmedical prescription tranquilizer use trends significantly differed comparing girls (3.9 to 10%) with boys (3.2 to 6.9%); stimulant use trends did not differ comparing girls (1.6 to 2.0%) with boys (2.0 to 1.3%). In Uruguay from 2007 to 2014 and 2014-2016, past-year nonmedical prescription tranquilizer (girls: 5.1 to 6.6%; boys: 2.8 to 4.2%) and stimulant (girls: 1.8 to 0.7%; boys: 1.8 to 0.7%) use trends did not differ by sex.

CONCLUSIONS

Trends of nonmedical prescription tranquilizer use recently increased in Chile and Uruguay, widening by sex over time in Chile only. The drivers of increasing tranquilizer use among girls in Chile and Uruguay merit further investigation.

Authors+Show Affiliations

Columbia University Mailman School of Public Health, 722 W 168th St, New York, NY, 10032, USA; Université Paris Descartes UMR1153, Hôpital Hôtel-Dieu, 1 Place du Parvis Notre-Dame, Paris, 75004, France. Electronic address: asp2183@cumc.columbia.edu.Center for Opioid Epidemiology and Policy, Department of Population Health, New York University School of Medicine, 180 Madison Avenue, New York, NY, 10016, USA; Department of Population Health, New York University School of Medicine, 180 Madison Avenue, New York, NY, 10016, USA.Columbia University Mailman School of Public Health, 722 W 168th St, New York, NY, 10032, USA.Department of Population Health, New York University School of Medicine, 180 Madison Avenue, New York, NY, 10016, USA; Society and Health Research Center, Facultad de Humanidades, Universidad Mayor, Badajoz 30, Santiago, Chile.Research Department, National Service for Prevention and Rehabilitation of Drug and Alcohol Use (SENDA), Agustinas 1235, 9th floor, Santiago, Chile.Dirección de Epidemiologia, Observatorio Argentino de Drogas, Calle Sarmiento 546, Ciudad Autónoma de Buenos Aires, C1041AAL, Argentina.Center for Opioid Epidemiology and Policy, Department of Population Health, New York University School of Medicine, 180 Madison Avenue, New York, NY, 10016, USA; Department of Population Health, New York University School of Medicine, 180 Madison Avenue, New York, NY, 10016, USA.Columbia University Mailman School of Public Health, 722 W 168th St, New York, NY, 10032, USA.

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

31606591

Citation

Perlmutter, Alexander S., et al. "Sex Differences in Nonmedical Prescription Tranquilizer and Stimulant Use Trends Among Secondary School Students in Argentina, Chile, and Uruguay." Drug and Alcohol Dependence, vol. 205, 2019, p. 107607.
Perlmutter AS, Rivera-Aguirre AE, Mauro PM, et al. Sex differences in nonmedical prescription tranquilizer and stimulant use trends among secondary school students in Argentina, Chile, and Uruguay. Drug Alcohol Depend. 2019;205:107607.
Perlmutter, A. S., Rivera-Aguirre, A. E., Mauro, P. M., Castillo-Carniglia, A., Rodriguez, N., Cadenas, N., Cerdá, M., & Martins, S. S. (2019). Sex differences in nonmedical prescription tranquilizer and stimulant use trends among secondary school students in Argentina, Chile, and Uruguay. Drug and Alcohol Dependence, 205, 107607. https://doi.org/10.1016/j.drugalcdep.2019.107607
Perlmutter AS, et al. Sex Differences in Nonmedical Prescription Tranquilizer and Stimulant Use Trends Among Secondary School Students in Argentina, Chile, and Uruguay. Drug Alcohol Depend. 2019 12 1;205:107607. PubMed PMID: 31606591.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sex differences in nonmedical prescription tranquilizer and stimulant use trends among secondary school students in Argentina, Chile, and Uruguay. AU - Perlmutter,Alexander S, AU - Rivera-Aguirre,Ariadne E, AU - Mauro,Pia M, AU - Castillo-Carniglia,Alvaro, AU - Rodriguez,Nicolás, AU - Cadenas,Nora, AU - Cerdá,Magdalena, AU - Martins,Silvia S, Y1 - 2019/10/04/ PY - 2018/12/31/received PY - 2019/07/31/revised PY - 2019/08/01/accepted PY - 2019/10/14/pubmed PY - 2020/7/1/medline PY - 2019/10/14/entrez KW - Adolescents KW - Epidemiology KW - Nonmedical prescription drug use KW - Nonmedical prescription stimulant use KW - Nonmedical prescription tranquilizer use KW - Trends SP - 107607 EP - 107607 JF - Drug and alcohol dependence JO - Drug Alcohol Depend VL - 205 N2 - BACKGROUND: Little is known about recent nonmedical prescription tranquilizer and stimulant use trends in Latin America. We tested whether recent trends among students in three South American countries differed by sex over time. METHODS: Three countries independently collected National School Students Survey on Drugs. Students in 8th, 10th, and 12th grades were sampled in Argentina (2007-2014, N = 328,202), Chile (2007-2015, N = 136,379), and Uruguay (2007-2016, N = 32,371). Weighted linear regression models predicted the prevalences and trends over time of past-year nonmedical tranquilizer and stimulant use by country, and tested whether trends differed by sex, adjusting for school type and grade. RESULTS: In Argentina from 2007 to 2014, past-year nonmedical prescription tranquilizer (girls: 2.8 to 2.6%, boys: 2.5 to 2.3%) and stimulant (girls: 1.7 to 1.3%, boys: 1.9 to 1.5%) use trends did not differ by sex. In Chile from 2007 to 2015, nonmedical prescription tranquilizer use trends significantly differed comparing girls (3.9 to 10%) with boys (3.2 to 6.9%); stimulant use trends did not differ comparing girls (1.6 to 2.0%) with boys (2.0 to 1.3%). In Uruguay from 2007 to 2014 and 2014-2016, past-year nonmedical prescription tranquilizer (girls: 5.1 to 6.6%; boys: 2.8 to 4.2%) and stimulant (girls: 1.8 to 0.7%; boys: 1.8 to 0.7%) use trends did not differ by sex. CONCLUSIONS: Trends of nonmedical prescription tranquilizer use recently increased in Chile and Uruguay, widening by sex over time in Chile only. The drivers of increasing tranquilizer use among girls in Chile and Uruguay merit further investigation. SN - 1879-0046 UR - https://www.unboundmedicine.com/medline/citation/31606591/Sex_differences_in_nonmedical_prescription_tranquilizer_and_stimulant_use_trends_among_secondary_school_students_in_Argentina_Chile_and_Uruguay_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0376-8716(19)30384-9 DB - PRIME DP - Unbound Medicine ER -