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[Correlation between chest CT features and clinical characteristics of patients with bronchiectasis].
Zhonghua Yi Xue Za Zhi 2019; 99(38):2982-2988ZY

Abstract

Objective:

To analyze the features of chest CT imaging in adult patients with bronchiectasis and explore its correlation with clinical characteristics.

Methods:

From January 2010 to December 2017, patients with bronchiectasis diagnosed by chest high-resolution CT (HRCT) and aged at or above 18 years old in 5 general hospitals of Shandong province were included in the study. The correlations between the HRCT imaging features and etiology, clinical manifestations, lung function, sputum culture, prognosis and other characteristics were analyzed.

Results:

There were 410 bronchiectasis patients included in the study. The chest HRCT imaging of bronchiectasis were divided into three types, including columnar 46.8%, cystic 45.9% and varicose 7.3%, respectively. The HRCT imaging score was [6.0 (4.0, 7.0)]. In addition, the most common etiology of bronchiectasis was idiopathic (262, 69.3%). The proportion of idiopathic bronchiectasis in cystic bronchiectasis patients was significantly higher than that in columnar and varicose bronchiectasis (71.8% vs 58.3%, 50.0%; both P<0.017). Compared with columnar bronchiectasis, patients with cystic bronchiectasis were more likely to suffer from clinical manifestations such as cough, dyspnea, fever and wet rales (P<0.017). Compared with patients with HRCT scores of 1 to 4, patients with scores ≥8 were more likely to suffer from cough, dyspnea, fever, wet rales and clubbing (P<0.017). The proportions of pulmonary ventilatory dysfunction were significantly greater in patients with cystic bronchiectasis and varicose bronchiectasis than columnar bronchiectasis (86.7%, 86.7% vs 51.0%; both P<0.017). The HRCT scores were significantly negatively correlated with pulmonary function (P<0.001). The number of acute exacerbations, hospitalizations, and bronchiectasis severe index scores in patients with cystic bronchiectasis were significantly higher than those with columnar bronchiectasis (P<0.017). There was a significantly positive correlation between HRCT scores and the number of acute exacerbations, hospitalizations and the bronchiectasis severity index scores (P<0.001). The mortality of patients with cystic and varicose bronchiectasis was significantly higher than that of patients with columnar bronchiectasis (9.0%, 10.0% vs 2.1%; both P<0.017). Compared with patients with HRCT scores of 1 to 4, patients with scores ≥8 had a higher mortality rate (15.9% vs 0.9%; P<0.017).

Conclusions:

There is a correlation between HRCT findings and clinical manifestations in patients with bronchiectasis. The clinical manifestations, lung function and prognosis of patients with cystic bronchiectasis are worse than those of the columnar bronchiectasis; the higher the HRCT scores are, the worse the clinical manifestations, lung function and prognosis of the patients are.

Authors+Show Affiliations

Departments of Respiratory Medicine, Heze Municipal Hospital, Heze 274031, China.Departments of Respiratory Medicine, Jinan City People' Hospital, Jinan 271100, China.Departments of Respiratory Medicine, Heze Municipal Hospital, Heze 274031, China.Departments of Respiratory Medicine, Qilu Hospital of Shandong University, Jinan 250012, China.

Pub Type(s)

Journal Article

Language

chi

PubMed ID

31607029

Citation

Wu, F J., et al. "[Correlation Between Chest CT Features and Clinical Characteristics of Patients With Bronchiectasis]." Zhonghua Yi Xue Za Zhi, vol. 99, no. 38, 2019, pp. 2982-2988.
Wu FJ, Qi Q, Hu Q, et al. [Correlation between chest CT features and clinical characteristics of patients with bronchiectasis]. Zhonghua Yi Xue Za Zhi. 2019;99(38):2982-2988.
Wu, F. J., Qi, Q., Hu, Q., & Xu, L. S. (2019). [Correlation between chest CT features and clinical characteristics of patients with bronchiectasis]. Zhonghua Yi Xue Za Zhi, 99(38), pp. 2982-2988. doi:10.3760/cma.j.issn.0376-2491.2019.38.004.
Wu FJ, et al. [Correlation Between Chest CT Features and Clinical Characteristics of Patients With Bronchiectasis]. Zhonghua Yi Xue Za Zhi. 2019 Oct 15;99(38):2982-2988. PubMed PMID: 31607029.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Correlation between chest CT features and clinical characteristics of patients with bronchiectasis]. AU - Wu,F J, AU - Qi,Q, AU - Hu,Q, AU - Xu,L S, PY - 2019/10/15/entrez PY - 2019/10/15/pubmed PY - 2019/11/8/medline KW - Bronchiectasis KW - Disease attributes KW - Lung KW - Tomography, X-ray computed SP - 2982 EP - 2988 JF - Zhonghua yi xue za zhi JO - Zhonghua Yi Xue Za Zhi VL - 99 IS - 38 N2 - Objective: To analyze the features of chest CT imaging in adult patients with bronchiectasis and explore its correlation with clinical characteristics. Methods: From January 2010 to December 2017, patients with bronchiectasis diagnosed by chest high-resolution CT (HRCT) and aged at or above 18 years old in 5 general hospitals of Shandong province were included in the study. The correlations between the HRCT imaging features and etiology, clinical manifestations, lung function, sputum culture, prognosis and other characteristics were analyzed. Results: There were 410 bronchiectasis patients included in the study. The chest HRCT imaging of bronchiectasis were divided into three types, including columnar 46.8%, cystic 45.9% and varicose 7.3%, respectively. The HRCT imaging score was [6.0 (4.0, 7.0)]. In addition, the most common etiology of bronchiectasis was idiopathic (262, 69.3%). The proportion of idiopathic bronchiectasis in cystic bronchiectasis patients was significantly higher than that in columnar and varicose bronchiectasis (71.8% vs 58.3%, 50.0%; both P<0.017). Compared with columnar bronchiectasis, patients with cystic bronchiectasis were more likely to suffer from clinical manifestations such as cough, dyspnea, fever and wet rales (P<0.017). Compared with patients with HRCT scores of 1 to 4, patients with scores ≥8 were more likely to suffer from cough, dyspnea, fever, wet rales and clubbing (P<0.017). The proportions of pulmonary ventilatory dysfunction were significantly greater in patients with cystic bronchiectasis and varicose bronchiectasis than columnar bronchiectasis (86.7%, 86.7% vs 51.0%; both P<0.017). The HRCT scores were significantly negatively correlated with pulmonary function (P<0.001). The number of acute exacerbations, hospitalizations, and bronchiectasis severe index scores in patients with cystic bronchiectasis were significantly higher than those with columnar bronchiectasis (P<0.017). There was a significantly positive correlation between HRCT scores and the number of acute exacerbations, hospitalizations and the bronchiectasis severity index scores (P<0.001). The mortality of patients with cystic and varicose bronchiectasis was significantly higher than that of patients with columnar bronchiectasis (9.0%, 10.0% vs 2.1%; both P<0.017). Compared with patients with HRCT scores of 1 to 4, patients with scores ≥8 had a higher mortality rate (15.9% vs 0.9%; P<0.017). Conclusions: There is a correlation between HRCT findings and clinical manifestations in patients with bronchiectasis. The clinical manifestations, lung function and prognosis of patients with cystic bronchiectasis are worse than those of the columnar bronchiectasis; the higher the HRCT scores are, the worse the clinical manifestations, lung function and prognosis of the patients are. SN - 0376-2491 UR - https://www.unboundmedicine.com/medline/citation/31607029/[Correlation_between_chest_CT_features_and_clinical_characteristics_of_patients_with_bronchiectasis] L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0376-2491&amp;year=2019&amp;vol=99&amp;issue=38&amp;fpage=2982 DB - PRIME DP - Unbound Medicine ER -