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Fibrate Medications

Abstract
The fibrates are a type of amphipathic carboxylic acids, belonging to the class of drugs used to lower serum cholesterol levels. They are currently the most important class of drugs combating the worldwide epidemic of atherogenic dyslipidemia. Statins definitely help reduce the levels of low-density lipoprotein cholesterol (LDL) but do not have much effect on serum triglyceride or HDL levels, where the use of fibrates is required. Research shows that the effects of different fibrate medications, while essentially being the same, also differ slightly with regards to their impact on glucose metabolism, insulin resistance, intermittent claudication, microvascular effects of diabetes mellitus; this provides the option of tailoring therapy as per the needs of every patient.[1] The FDA approved indications of fibrates include :

Publisher

StatPearls Publishing
Treasure Island (FL)

Language

eng

PubMed ID

31613536

Citation

Singh G, Correa R: Fibrate Medications.StatPearls. StatPearls Publishing, 2019, Treasure Island (FL).
Singh G, Correa R. Fibrate Medications. StatPearls. Treasure Island (FL): StatPearls Publishing; 2019.
Singh G & Correa R. (2019). Fibrate Medications. In StatPearls. Treasure Island (FL): StatPearls Publishing;
Singh G, Correa R. StatPearls. Treasure Island (FL): StatPearls Publishing; 2019.
* Article titles in AMA citation format should be in sentence-case
TY - CHAP T1 - Fibrate Medications BT - StatPearls A1 - Singh,Gauri, AU - Correa,Ricardo, Y1 - 2019/01// PY - 2019/10/16/pubmed PY - 2019/10/16/medline PY - 2019/10/16/entrez N2 - The fibrates are a type of amphipathic carboxylic acids, belonging to the class of drugs used to lower serum cholesterol levels. They are currently the most important class of drugs combating the worldwide epidemic of atherogenic dyslipidemia. Statins definitely help reduce the levels of low-density lipoprotein cholesterol (LDL) but do not have much effect on serum triglyceride or HDL levels, where the use of fibrates is required. Research shows that the effects of different fibrate medications, while essentially being the same, also differ slightly with regards to their impact on glucose metabolism, insulin resistance, intermittent claudication, microvascular effects of diabetes mellitus; this provides the option of tailoring therapy as per the needs of every patient.[1] The FDA approved indications of fibrates include : PB - StatPearls Publishing CY - Treasure Island (FL) UR - https://www.unboundmedicine.com/medline/citation/31613536/StatPearls:_Fibrate_Medications L2 - https://www.ncbi.nlm.nih.gov/books/NBK547756 DB - PRIME DP - Unbound Medicine ER -
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