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A Rare Case of Atrophic Dermatofibroma Featuring Linear Skin Dimple.
Case Rep Dermatol 2019 Sep-Dec; 11(3):256-259CR

Abstract

Dermatofibroma (DF) is a benign skin tumor that is well-known among dermatologists. We herein present a rare case of atrophic dermatofibroma presenting linear skin dimpling. The patient was a 25-year-old woman with a history of wild-type recessive dystrophic epidermolysis bullosa who had noticed linear concavity on her right lateral back 1 year before her initial presentation. Anetoderma, atrophic scar, localized morphea, or lupus erythematosus profundus were clinically suspected; however, a biopsy specimen from the dimpling lesion showed the fibrous and histiocytic tumor in the deep dermis. The spindle-to-rhomboid-shaped tumor cells were arranged with irregularly storiform pattern, and immunohistochemistry showed that the tumor cells were positive for factor XIIIa, and negative for CD34 and CD68. Elastica van Gieson staining showed an almost complete loss of elastic fibers, especially at the center of the lesion. The reduction of elastic fibers might have influenced the skin depression in this case. This rare case suggests the need to consider a subtype of DF in the differential diagnosis of dimpling skin lesions.

Authors+Show Affiliations

Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan.Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan.Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan.Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan.Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

31616278

Citation

Takafuji, Madoka, et al. "A Rare Case of Atrophic Dermatofibroma Featuring Linear Skin Dimple." Case Reports in Dermatology, vol. 11, no. 3, 2019, pp. 256-259.
Takafuji M, Tanemura A, Hanaoka Y, et al. A Rare Case of Atrophic Dermatofibroma Featuring Linear Skin Dimple. Case Rep Dermatol. 2019;11(3):256-259.
Takafuji, M., Tanemura, A., Hanaoka, Y., Tamai, K., & Fujimoto, M. (2019). A Rare Case of Atrophic Dermatofibroma Featuring Linear Skin Dimple. Case Reports in Dermatology, 11(3), pp. 256-259. doi:10.1159/000503413.
Takafuji M, et al. A Rare Case of Atrophic Dermatofibroma Featuring Linear Skin Dimple. Case Rep Dermatol. 2019;11(3):256-259. PubMed PMID: 31616278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A Rare Case of Atrophic Dermatofibroma Featuring Linear Skin Dimple. AU - Takafuji,Madoka, AU - Tanemura,Atsushi, AU - Hanaoka,Yuma, AU - Tamai,Katsuto, AU - Fujimoto,Manabu, Y1 - 2019/09/30/ PY - 2019/07/26/received PY - 2019/09/12/accepted PY - 2019/10/17/entrez PY - 2019/10/17/pubmed PY - 2019/10/17/medline KW - Atrophic dermatofibroma KW - Elastic fiber KW - Epidermolysis bullosa KW - Linear skin dimple KW - Rare case SP - 256 EP - 259 JF - Case reports in dermatology JO - Case Rep Dermatol VL - 11 IS - 3 N2 - Dermatofibroma (DF) is a benign skin tumor that is well-known among dermatologists. We herein present a rare case of atrophic dermatofibroma presenting linear skin dimpling. The patient was a 25-year-old woman with a history of wild-type recessive dystrophic epidermolysis bullosa who had noticed linear concavity on her right lateral back 1 year before her initial presentation. Anetoderma, atrophic scar, localized morphea, or lupus erythematosus profundus were clinically suspected; however, a biopsy specimen from the dimpling lesion showed the fibrous and histiocytic tumor in the deep dermis. The spindle-to-rhomboid-shaped tumor cells were arranged with irregularly storiform pattern, and immunohistochemistry showed that the tumor cells were positive for factor XIIIa, and negative for CD34 and CD68. Elastica van Gieson staining showed an almost complete loss of elastic fibers, especially at the center of the lesion. The reduction of elastic fibers might have influenced the skin depression in this case. This rare case suggests the need to consider a subtype of DF in the differential diagnosis of dimpling skin lesions. SN - 1662-6567 UR - https://www.unboundmedicine.com/medline/citation/31616278/A_Rare_Case_of_Atrophic_Dermatofibroma_Featuring_Linear_Skin_Dimple L2 - https://www.karger.com?DOI=10.1159/000503413 DB - PRIME DP - Unbound Medicine ER -