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Mitigation of Primary Graft Dysfunction in Lung Transplantation: Current Understanding and Hopes for the Future.
Semin Cardiothorac Vasc Anesth 2019; :1089253219881980SC

Abstract

Primary graft dysfunction (PGD) is a form of acute lung injury that develops within the first 72 hours after lung transplantation. The overall incidence of PGD is estimated to be around 30%, and the 30-day mortality for grade 3 PGD around 36%. PGD is also associated with the development of bronchiolitis obliterans syndrome, a specific form of chronic lung allograft dysfunction. In this article, we will discuss perioperative strategies for PGD prevention as well as possible future avenues for prevention and treatment.

Authors+Show Affiliations

University of Colorado Denver, Aurora, CO, USA.University of Colorado Denver, Aurora, CO, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31617450

Citation

Wilkey, Barbara J., and Benjamin A. Abrams. "Mitigation of Primary Graft Dysfunction in Lung Transplantation: Current Understanding and Hopes for the Future." Seminars in Cardiothoracic and Vascular Anesthesia, 2019, p. 1089253219881980.
Wilkey BJ, Abrams BA. Mitigation of Primary Graft Dysfunction in Lung Transplantation: Current Understanding and Hopes for the Future. Semin Cardiothorac Vasc Anesth. 2019.
Wilkey, B. J., & Abrams, B. A. (2019). Mitigation of Primary Graft Dysfunction in Lung Transplantation: Current Understanding and Hopes for the Future. Seminars in Cardiothoracic and Vascular Anesthesia, p. 1089253219881980. doi:10.1177/1089253219881980.
Wilkey BJ, Abrams BA. Mitigation of Primary Graft Dysfunction in Lung Transplantation: Current Understanding and Hopes for the Future. Semin Cardiothorac Vasc Anesth. 2019 Oct 16;1089253219881980. PubMed PMID: 31617450.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mitigation of Primary Graft Dysfunction in Lung Transplantation: Current Understanding and Hopes for the Future. AU - Wilkey,Barbara J, AU - Abrams,Benjamin A, Y1 - 2019/10/16/ PY - 2019/10/17/entrez KW - cardiac anesthesia KW - cardiopulmonary bypass surgery KW - lung transplantation KW - primary graft dysfunction KW - thoracic surgery KW - transplantation SP - 1089253219881980 EP - 1089253219881980 JF - Seminars in cardiothoracic and vascular anesthesia JO - Semin Cardiothorac Vasc Anesth N2 - Primary graft dysfunction (PGD) is a form of acute lung injury that develops within the first 72 hours after lung transplantation. The overall incidence of PGD is estimated to be around 30%, and the 30-day mortality for grade 3 PGD around 36%. PGD is also associated with the development of bronchiolitis obliterans syndrome, a specific form of chronic lung allograft dysfunction. In this article, we will discuss perioperative strategies for PGD prevention as well as possible future avenues for prevention and treatment. SN - 1940-5596 UR - https://www.unboundmedicine.com/medline/citation/31617450/Mitigation_of_Primary_Graft_Dysfunction_in_Lung_Transplantation:_Current_Understanding_and_Hopes_for_the_Future L2 - http://journals.sagepub.com/doi/full/10.1177/1089253219881980?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -