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Add-on grade-ranking scale for assessing thrombotic risk in patients with ischemic heart disease and percutaneous coronary angioplasty.
Wiad Lek 2019; 72(9 cz 2):1727-1731WL

Abstract

OBJECTIVE

Introduction: The anticipation of the development of thrombotic complications in coronary angioplasty patients helps to prevent this dangerous complication. Development of the available informative scales on the basis of mathematical methods taking into account the main clinical and biochemical parameters significantly simplifies the classification of patients in terms of thrombotic risk. The aim of the paper is to concentrate information on the state of hemostasis in the studied category of patients using the method of the main components and to obtain a matrix with minimal loss of information, which is convenient for analysis and the creation of a grade-ranking scale.

PATIENTS AND METHODS

Materials and methods: Data of 70 patients with coronary heart disease and percutaneous coronary angioplasty were analyzed. The level of soluble fibrin, fibrinogen, D-dimer, protein C, and ratios rf/dd×100 were determined, and also the presence of diabetes mellitus and restenosis in the history was considered.

RESULTS

Results: As a result of a stepwise study using the method of the main components, in the first stage two most singular matrices were obtained that describe 70% of the entire data variance (one of them is the component rf+dd, and the second one is fg+pc), which led to the first indicator of the level of thrombotic risk. At the second stage, the level of thrombotic risk was clarified, taking into consideration the presence of diabetes and history of restenosis, and it is recommended to use a second indicator for its determination (rf/dd×100).

CONCLUSION

Conclusions: The presented grade-ranking scale scale allows the anticipation of the development of thrombotic complications in the studied category of patients with high probability.

Authors+Show Affiliations

National Pirogov Memorial Medical University, Vinnytsia, Ukraine.Vinnytsia Mykhailo Kotsiubynskyi State Pedagogical University, Vinnytsia, Ukraine.National Pirogov Memorial Medical University, Vinnytsia, Ukraine.Institute Of Rehabilitation Of The Disabled Of National Pirogov Memorial Medical University, Vinnytsia, Ukraine.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31622255

Citation

Storozhuk, Nadezhda V., et al. "Add-on Grade-ranking Scale for Assessing Thrombotic Risk in Patients With Ischemic Heart Disease and Percutaneous Coronary Angioplasty." Wiadomosci Lekarskie (Warsaw, Poland : 1960), vol. 72, no. 9 cz 2, 2019, pp. 1727-1731.
Storozhuk NV, Panasenko AB, Storozhuk BG, et al. Add-on grade-ranking scale for assessing thrombotic risk in patients with ischemic heart disease and percutaneous coronary angioplasty. Wiad Lek. 2019;72(9 cz 2):1727-1731.
Storozhuk, N. V., Panasenko, A. B., Storozhuk, B. G., & Dovgalyuk, T. V. (2019). Add-on grade-ranking scale for assessing thrombotic risk in patients with ischemic heart disease and percutaneous coronary angioplasty. Wiadomosci Lekarskie (Warsaw, Poland : 1960), 72(9 cz 2), pp. 1727-1731.
Storozhuk NV, et al. Add-on Grade-ranking Scale for Assessing Thrombotic Risk in Patients With Ischemic Heart Disease and Percutaneous Coronary Angioplasty. Wiad Lek. 2019;72(9 cz 2):1727-1731. PubMed PMID: 31622255.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Add-on grade-ranking scale for assessing thrombotic risk in patients with ischemic heart disease and percutaneous coronary angioplasty. AU - Storozhuk,Nadezhda V, AU - Panasenko,Aleksey B, AU - Storozhuk,Boris G, AU - Dovgalyuk,Tatiana V, PY - 2019/10/18/entrez PY - 2019/10/18/pubmed PY - 2019/11/8/medline KW - coronary angioplasty KW - hemostasis KW - method of main components KW - thrombotic risk SP - 1727 EP - 1731 JF - Wiadomosci lekarskie (Warsaw, Poland : 1960) JO - Wiad. Lek. VL - 72 IS - 9 cz 2 N2 - OBJECTIVE: Introduction: The anticipation of the development of thrombotic complications in coronary angioplasty patients helps to prevent this dangerous complication. Development of the available informative scales on the basis of mathematical methods taking into account the main clinical and biochemical parameters significantly simplifies the classification of patients in terms of thrombotic risk. The aim of the paper is to concentrate information on the state of hemostasis in the studied category of patients using the method of the main components and to obtain a matrix with minimal loss of information, which is convenient for analysis and the creation of a grade-ranking scale. PATIENTS AND METHODS: Materials and methods: Data of 70 patients with coronary heart disease and percutaneous coronary angioplasty were analyzed. The level of soluble fibrin, fibrinogen, D-dimer, protein C, and ratios rf/dd×100 were determined, and also the presence of diabetes mellitus and restenosis in the history was considered. RESULTS: Results: As a result of a stepwise study using the method of the main components, in the first stage two most singular matrices were obtained that describe 70% of the entire data variance (one of them is the component rf+dd, and the second one is fg+pc), which led to the first indicator of the level of thrombotic risk. At the second stage, the level of thrombotic risk was clarified, taking into consideration the presence of diabetes and history of restenosis, and it is recommended to use a second indicator for its determination (rf/dd×100). CONCLUSION: Conclusions: The presented grade-ranking scale scale allows the anticipation of the development of thrombotic complications in the studied category of patients with high probability. SN - 0043-5147 UR - https://www.unboundmedicine.com/medline/citation/31622255/Add-on_grade-ranking_scale_for_assessing_thrombotic_risk_in_patients_with_ischemic_heart_disease_and_percutaneous_coronary_angioplasty DB - PRIME DP - Unbound Medicine ER -