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Enormous gastrointestinal stromal tumor arising from the stomach causing weight loss and anemia in an elderly female: Case report.
Int J Surg Case Rep 2019; 64:102-104IJ

Abstract

INTRODUCTION

Gastrointestinal stromal tumors are the most common mesenchymal tumors of gastrointestinal tract originating from the interstitial cell of Cajal. The presentation is variable depending on the size and site. CT scan is the most widely used imaging. The primary treatment is surgical resection. Imatinib may be used in unresectable tumors or preoperatively.

CASE PRESENTATION

A 65-year-old lady had weight loss and repeated vomiting for one year. Examination showed a non-tender mass in the left hypochonrdium arising below the costal margin extending to 15 cm toward the left iliac fossa. It was firm with smooth surface. CT-scan examination showed a 45 cm × 21 cm mass arising between the spleen and the left kidney and displacing the kidney toward the midline. Gastroscopy and biopsy showed gastrointestinal stromal tumor. During surgery an enormous gastric tumor attached to the spleen. Total gastrectomy en-block with splenectomy and reconstruction done through roux-en-y esophago-jejunostomy and jejunojejunostomy.

CONCLUSION

GISTs most commonly affect the stomach, most tumors are treated by primary surgical excision with normal safety margins, advanced disease may need imatinib before surgery which helps in decreasing the size of the tumor and makes surgery easier.

Authors+Show Affiliations

Department of Surgery, College of Medicine, University of Duhok, Kurdistan Region, Iraq. Electronic address: ayad.mohammed@uod.ac.Department of Surgery, College of Medicine, University of Duhok, Kurdistan Region, Iraq.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31622929

Citation

Mohammed, Ayad Ahmad, and Sardar Hassan Arif. "Enormous Gastrointestinal Stromal Tumor Arising From the Stomach Causing Weight Loss and Anemia in an Elderly Female: Case Report." International Journal of Surgery Case Reports, vol. 64, 2019, pp. 102-104.
Mohammed AA, Arif SH. Enormous gastrointestinal stromal tumor arising from the stomach causing weight loss and anemia in an elderly female: Case report. Int J Surg Case Rep. 2019;64:102-104.
Mohammed, A. A., & Arif, S. H. (2019). Enormous gastrointestinal stromal tumor arising from the stomach causing weight loss and anemia in an elderly female: Case report. International Journal of Surgery Case Reports, 64, pp. 102-104. doi:10.1016/j.ijscr.2019.09.045.
Mohammed AA, Arif SH. Enormous Gastrointestinal Stromal Tumor Arising From the Stomach Causing Weight Loss and Anemia in an Elderly Female: Case Report. Int J Surg Case Rep. 2019;64:102-104. PubMed PMID: 31622929.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Enormous gastrointestinal stromal tumor arising from the stomach causing weight loss and anemia in an elderly female: Case report. AU - Mohammed,Ayad Ahmad, AU - Arif,Sardar Hassan, Y1 - 2019/10/10/ PY - 2019/08/12/received PY - 2019/09/25/revised PY - 2019/09/30/accepted PY - 2019/10/18/pubmed PY - 2019/10/18/medline PY - 2019/10/18/entrez KW - CD117 KW - GIST KW - Gastrointestinal stromal tumors KW - Imatinib KW - Interstitial cell of Cajal KW - c-kit protein SP - 102 EP - 104 JF - International journal of surgery case reports JO - Int J Surg Case Rep VL - 64 N2 - INTRODUCTION: Gastrointestinal stromal tumors are the most common mesenchymal tumors of gastrointestinal tract originating from the interstitial cell of Cajal. The presentation is variable depending on the size and site. CT scan is the most widely used imaging. The primary treatment is surgical resection. Imatinib may be used in unresectable tumors or preoperatively. CASE PRESENTATION: A 65-year-old lady had weight loss and repeated vomiting for one year. Examination showed a non-tender mass in the left hypochonrdium arising below the costal margin extending to 15 cm toward the left iliac fossa. It was firm with smooth surface. CT-scan examination showed a 45 cm × 21 cm mass arising between the spleen and the left kidney and displacing the kidney toward the midline. Gastroscopy and biopsy showed gastrointestinal stromal tumor. During surgery an enormous gastric tumor attached to the spleen. Total gastrectomy en-block with splenectomy and reconstruction done through roux-en-y esophago-jejunostomy and jejunojejunostomy. CONCLUSION: GISTs most commonly affect the stomach, most tumors are treated by primary surgical excision with normal safety margins, advanced disease may need imatinib before surgery which helps in decreasing the size of the tumor and makes surgery easier. SN - 2210-2612 UR - https://www.unboundmedicine.com/medline/citation/31622929/Enormous_gastrointestinal_stromal_tumor_arising_from_the_stomach_causing_weight_loss_and_anemia_in_an_elderly_female:_Case_report L2 - https://linkinghub.elsevier.com/retrieve/pii/S2210-2612(19)30548-6 DB - PRIME DP - Unbound Medicine ER -