Tags

Type your tag names separated by a space and hit enter

Heterogeneity of tyrosine hydroxylase expressing neurons in the main olfactory bulb of the mouse.

Abstract

The structural features of dopamine (DA)-GABAergic neurons in the mouse main olfactory bulbs were examined, using both wild type and transgenic TH-GFP mice, with the combination of several methods; the immunocytochemistry, biotinylated dextran amine labeling, lucifer yellow injection in fixed slices, biocytin injection in live slice and the functional olfactory deprivation. DA-GABAergic neurons were clustered in the glomerular layer (GL) but they also scattered in other layers. DA-GABAergic juxtaglomerular neurons, were classified into 5 groups based on their structural features and named as follows: 1) Large periglomerular (LPG) cells with tuft-like glomerular dendritic branches and apparent axons extending to the distant glomeruli, which correspond to the " inhibitory juxtaglomerular association (IJGA) neurons" participating in the interglomerular association system. 2) Small periglomerular (SPG) cells including both axonic and anaxonic ones; the axonic SPG cells might correspond to the classical periglomerular cells. 3) Transglomerular cells extending dendritic processes spanning 2 or more glomeruli. 4) Incrusting cells extending their dendritic branches mainly in the periphery of the glomeruli. 5) Other various neurons not-yet classified. In the layers other than the GL various types of TH expressing neurons were scattered; some of them extended dendritic processes into the GL.

Authors+Show Affiliations

Department of Medical Science Technology, Faculty of Health and Welfare Sciences in Fukuoka, International University of Health and Welfare, 137-1 Enokizu, Okawa City, Fukuoka 831-8501, Japan. Electronic address: t-kosaka@iuhw.ac.jp.Department of Biomedical and Specialty Surgical Sciences, Physiology Section, University of Ferrara, Via Borsari 46, Ferrara, Italy.Department of Physical Therapy, Fukuoka International University of Health and Welfare, 3-6-40 Momochihama, Sawara-ku, Fukuoka 814-0001, Japan.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31629793

Citation

Kosaka, Toshio, et al. "Heterogeneity of Tyrosine Hydroxylase Expressing Neurons in the Main Olfactory Bulb of the Mouse." Neuroscience Research, 2019.
Kosaka T, Pignatelli A, Kosaka K. Heterogeneity of tyrosine hydroxylase expressing neurons in the main olfactory bulb of the mouse. Neurosci Res. 2019.
Kosaka, T., Pignatelli, A., & Kosaka, K. (2019). Heterogeneity of tyrosine hydroxylase expressing neurons in the main olfactory bulb of the mouse. Neuroscience Research, doi:10.1016/j.neures.2019.10.004.
Kosaka T, Pignatelli A, Kosaka K. Heterogeneity of Tyrosine Hydroxylase Expressing Neurons in the Main Olfactory Bulb of the Mouse. Neurosci Res. 2019 Oct 17; PubMed PMID: 31629793.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Heterogeneity of tyrosine hydroxylase expressing neurons in the main olfactory bulb of the mouse. AU - Kosaka,Toshio, AU - Pignatelli,Angela, AU - Kosaka,Katsuko, Y1 - 2019/10/17/ PY - 2019/08/19/received PY - 2019/09/29/revised PY - 2019/10/04/accepted PY - 2019/10/21/pubmed PY - 2019/10/21/medline PY - 2019/10/21/entrez KW - Ankyrin G KW - Axon KW - Axon initial segment KW - Dendrite KW - Glomerulus KW - Immunohistochemistry KW - Short-axon cell JF - Neuroscience research JO - Neurosci. Res. N2 - The structural features of dopamine (DA)-GABAergic neurons in the mouse main olfactory bulbs were examined, using both wild type and transgenic TH-GFP mice, with the combination of several methods; the immunocytochemistry, biotinylated dextran amine labeling, lucifer yellow injection in fixed slices, biocytin injection in live slice and the functional olfactory deprivation. DA-GABAergic neurons were clustered in the glomerular layer (GL) but they also scattered in other layers. DA-GABAergic juxtaglomerular neurons, were classified into 5 groups based on their structural features and named as follows: 1) Large periglomerular (LPG) cells with tuft-like glomerular dendritic branches and apparent axons extending to the distant glomeruli, which correspond to the " inhibitory juxtaglomerular association (IJGA) neurons" participating in the interglomerular association system. 2) Small periglomerular (SPG) cells including both axonic and anaxonic ones; the axonic SPG cells might correspond to the classical periglomerular cells. 3) Transglomerular cells extending dendritic processes spanning 2 or more glomeruli. 4) Incrusting cells extending their dendritic branches mainly in the periphery of the glomeruli. 5) Other various neurons not-yet classified. In the layers other than the GL various types of TH expressing neurons were scattered; some of them extended dendritic processes into the GL. SN - 1872-8111 UR - https://www.unboundmedicine.com/medline/citation/31629793/Heterogeneity_of_tyrosine_hydroxylase_expressing_neurons_in_the_main_olfactory_bulb_of_the_mouse L2 - https://linkinghub.elsevier.com/retrieve/pii/S0168-0102(19)30471-7 DB - PRIME DP - Unbound Medicine ER -