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Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn.
Case Rep Pediatr 2019; 2019:3476508CR

Abstract

The differential diagnosis of a congenital cutaneous vascular-appearing mass in a newborn is broad and includes both benign and malignant tumors. We report the case of a newborn who presented with an erythematous exophytic skin nodule on the right upper leg. Excision was performed due to ulceration, concern for bleeding, and for diagnosis. Pathology revealed the mass to be an infantile myofibroma. This case highlights the importance of considering a broad differential diagnosis in a newborn with a cutaneous mass. While history, physical exam, and imaging can help diagnose some cases, a biopsy or excision is often needed to distinguish benign lesions from more concerning lesions.

Authors+Show Affiliations

Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois, USA. Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois, USA.Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois, USA. Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

31637076

Citation

Shahzad, Farooq, et al. "Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn." Case Reports in Pediatrics, vol. 2019, 2019, p. 3476508.
Shahzad F, Chappell AG, Purnell CA, et al. Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn. Case Rep Pediatr. 2019;2019:3476508.
Shahzad, F., Chappell, A. G., Purnell, C. A., Aldulescu, M., & Chamlin, S. (2019). Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn. Case Reports in Pediatrics, 2019, p. 3476508. doi:10.1155/2019/3476508.
Shahzad F, et al. Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn. Case Rep Pediatr. 2019;2019:3476508. PubMed PMID: 31637076.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Infantile Myofibroma Presenting as a Large Ulcerative Nodule in a Newborn. AU - Shahzad,Farooq, AU - Chappell,Ava G, AU - Purnell,Chad A, AU - Aldulescu,Monica, AU - Chamlin,Sarah, Y1 - 2019/09/17/ PY - 2019/04/11/received PY - 2019/08/30/accepted PY - 2019/10/23/entrez PY - 2019/10/23/pubmed PY - 2019/10/23/medline SP - 3476508 EP - 3476508 JF - Case reports in pediatrics JO - Case Rep Pediatr VL - 2019 N2 - The differential diagnosis of a congenital cutaneous vascular-appearing mass in a newborn is broad and includes both benign and malignant tumors. We report the case of a newborn who presented with an erythematous exophytic skin nodule on the right upper leg. Excision was performed due to ulceration, concern for bleeding, and for diagnosis. Pathology revealed the mass to be an infantile myofibroma. This case highlights the importance of considering a broad differential diagnosis in a newborn with a cutaneous mass. While history, physical exam, and imaging can help diagnose some cases, a biopsy or excision is often needed to distinguish benign lesions from more concerning lesions. SN - 2090-6803 UR - https://www.unboundmedicine.com/medline/citation/31637076/Infantile_Myofibroma_Presenting_as_a_Large_Ulcerative_Nodule_in_a_Newborn L2 - https://dx.doi.org/10.1155/2019/3476508 DB - PRIME DP - Unbound Medicine ER -