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Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka.
BMC Cardiovasc Disord. 2019 10 21; 19(1):229.BC

Abstract

BACKGROUND

Acute Coronary Syndrome (ACS) is one of the leading causes of death worldwide and studies have shown higher mortality rates and premature death in South Asian countries. The occurrence and effect of risk factors differ by type ofACS.Epidemiological studies in the Sri Lankan population are limited.

METHODS

This is a cross sectional descriptive study conducted at the Teaching Hospital Peradeniya, Sri Lanka among patients presenting with ACS. Data was collected by an interviewer administered structured questionnaire and epidemiological patterns and risk factors were analyzed.

RESULTS

The sample of 300 patients had a mean age of 61.3+/- 12.6 and male sex showed higher association with all three type of ACS compared to female with a P value of 0.001. This study showed higher mean age of 62.2 ± 11.4 years amongst unstable angina (UA) patients and 61.9 ± 14.5 years amongst non ST elevation myocardial infarction (NSTEMI) patients compared to 59.2 ± 11.2 years for ST elevation myocardial infarction (STEMI) patients with no significant statistical difference (P = 0.246). Approximately 55.8% STEMI patients, 39.8% UA and 35.5% NSTEMI patients were smokers indicating a significant association between smoking and STEMI (P = 0.017). Nearly 54.5% STEMI, 35.4% UA and 32.7% NSTEMI patients consumed alcohol and there was a very strong association between alcohol consumption and STEMI (P = 0.006). Almost 51.8% NSTEMI patients, 47.8% UA patients and 29.9% STEMI patients had hypertension(HT) (P = 0.008) indicating significant association of HT with UA and NSTEMI. About 33.6% UA patients and 30.0% NSTEMI patients had DM whilst only 22.1% of STEMI patients had DM of no significance (p = 0.225). Around 15.0% patients with UA, 25.5% with NSTEMI and 11.7% with STEMI had dyslipidemia (P = 0.032). There was a very strong association between a past history of ACS or stable angina with NSTEMI and UA (P = 0.001).

CONCLUSION

Smoking and alcohol abuse are significantly associated with STEMI.Patients with NSTEMI or Unstable Angina had higher rates of hypertension and were more likely to have a history of ACS or stable angina than STEMI patients. Patients with NSTEMI were more likely than patients with STEMI or UA to have dyslipidemia.

Authors+Show Affiliations

Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka. udayapralapanawa@yahoo.com.Department of Community Medicine, University of Peradeniya, Peradeniya, Sri Lanka.Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.Teaching Hospital Peradeniya, Peradeniya, Sri Lanka.Teaching Hospital Peradeniya, Peradeniya, Sri Lanka.Department of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.Teaching Hospital Peradeniya, Peradeniya, Sri Lanka.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

31638908

Citation

Ralapanawa, Udaya, et al. "Epidemiology and Risk Factors of Patients With Types of Acute Coronary Syndrome Presenting to a Tertiary Care Hospital in Sri Lanka." BMC Cardiovascular Disorders, vol. 19, no. 1, 2019, p. 229.
Ralapanawa U, Kumarasiri PVR, Jayawickreme KP, et al. Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka. BMC Cardiovasc Disord. 2019;19(1):229.
Ralapanawa, U., Kumarasiri, P. V. R., Jayawickreme, K. P., Kumarihamy, P., Wijeratne, Y., Ekanayake, M., & Dissanayake, C. (2019). Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka. BMC Cardiovascular Disorders, 19(1), 229. https://doi.org/10.1186/s12872-019-1217-x
Ralapanawa U, et al. Epidemiology and Risk Factors of Patients With Types of Acute Coronary Syndrome Presenting to a Tertiary Care Hospital in Sri Lanka. BMC Cardiovasc Disord. 2019 10 21;19(1):229. PubMed PMID: 31638908.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiology and risk factors of patients with types of acute coronary syndrome presenting to a tertiary care hospital in Sri Lanka. AU - Ralapanawa,Udaya, AU - Kumarasiri,Pallegoda Vithanage Ranjith, AU - Jayawickreme,Kushalee Poornima, AU - Kumarihamy,Prabashini, AU - Wijeratne,Yapa, AU - Ekanayake,Madhushanka, AU - Dissanayake,Chandira, Y1 - 2019/10/21/ PY - 2018/07/08/received PY - 2019/10/04/accepted PY - 2019/10/23/entrez PY - 2019/10/23/pubmed PY - 2019/10/23/medline KW - Acute coronary syndrome KW - Non-ST elevation myocardial infarction KW - ST elevation myocardial infarction KW - Sri Lanka KW - Unstable angina SP - 229 EP - 229 JF - BMC cardiovascular disorders JO - BMC Cardiovasc Disord VL - 19 IS - 1 N2 - BACKGROUND: Acute Coronary Syndrome (ACS) is one of the leading causes of death worldwide and studies have shown higher mortality rates and premature death in South Asian countries. The occurrence and effect of risk factors differ by type ofACS.Epidemiological studies in the Sri Lankan population are limited. METHODS: This is a cross sectional descriptive study conducted at the Teaching Hospital Peradeniya, Sri Lanka among patients presenting with ACS. Data was collected by an interviewer administered structured questionnaire and epidemiological patterns and risk factors were analyzed. RESULTS: The sample of 300 patients had a mean age of 61.3+/- 12.6 and male sex showed higher association with all three type of ACS compared to female with a P value of 0.001. This study showed higher mean age of 62.2 ± 11.4 years amongst unstable angina (UA) patients and 61.9 ± 14.5 years amongst non ST elevation myocardial infarction (NSTEMI) patients compared to 59.2 ± 11.2 years for ST elevation myocardial infarction (STEMI) patients with no significant statistical difference (P = 0.246). Approximately 55.8% STEMI patients, 39.8% UA and 35.5% NSTEMI patients were smokers indicating a significant association between smoking and STEMI (P = 0.017). Nearly 54.5% STEMI, 35.4% UA and 32.7% NSTEMI patients consumed alcohol and there was a very strong association between alcohol consumption and STEMI (P = 0.006). Almost 51.8% NSTEMI patients, 47.8% UA patients and 29.9% STEMI patients had hypertension(HT) (P = 0.008) indicating significant association of HT with UA and NSTEMI. About 33.6% UA patients and 30.0% NSTEMI patients had DM whilst only 22.1% of STEMI patients had DM of no significance (p = 0.225). Around 15.0% patients with UA, 25.5% with NSTEMI and 11.7% with STEMI had dyslipidemia (P = 0.032). There was a very strong association between a past history of ACS or stable angina with NSTEMI and UA (P = 0.001). CONCLUSION: Smoking and alcohol abuse are significantly associated with STEMI.Patients with NSTEMI or Unstable Angina had higher rates of hypertension and were more likely to have a history of ACS or stable angina than STEMI patients. Patients with NSTEMI were more likely than patients with STEMI or UA to have dyslipidemia. SN - 1471-2261 UR - https://www.unboundmedicine.com/medline/citation/31638908/Epidemiology_and_risk_factors_of_patients_with_types_of_acute_coronary_syndrome_presenting_to_a_tertiary_care_hospital_in_Sri_Lanka_ L2 - https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-019-1217-x DB - PRIME DP - Unbound Medicine ER -