Tags

Type your tag names separated by a space and hit enter

Follow-Up After Catheter Ablation of Papillary Muscles and Valve Cusps.
JACC Clin Electrophysiol 2019; 5(10):1185-1196JC

Abstract

OBJECTIVES

The goal of this study was to determine the impact of catheter ablation in the region of papillary muscles (PMs) and valvular cusps (VC) on mitral, tricuspid, or aortic valve function.

BACKGROUND

Ventricular arrhythmias arising from PMs and VCs often require extensive catheter ablation. Little is known regarding the risk of valve dysfunction after radiofrequency catheter ablation of such arrhythmias.

METHODS

A retrospective analysis was completed for 149 PM and VC VT/premature ventricular contraction (PVC) ablations from 2008 to 2018 at our institution. Patient and procedural details were collected for VT and PVC ablation cases involving PMs and VCs with available echocardiographic data pre-ablation and post-ablation (within 6 months). Degree of valvular regurgitation (VR) was graded from 0 (none) to 4 (severe), and significant valvular dysfunction was defined as a 2+ change in VR.

RESULTS

Of 149 radiofrequency catheter ablation cases, there were 84 (56%) aortic valve cusp ablations, 60 (40%) left ventricular PM ablations, and 5 (3%) right ventricular PM ablations. There were no statistically significant differences between pre-ablation and post-ablation VR severity (p = 0.33). No patients had a 2+ grade change in VR severity when pre-ablation and post-ablation echocardiograms were compared. There were no significant sequelae requiring intervention in the post-ablation period. On follow-up of 36 ± 9 months, for those with a change in VR, the severity had improved to baseline or remained stable.

CONCLUSIONS

Despite often-times extensive ablation on and around valvular networks, risk of longstanding or permanent valvular dysfunction after VT/PVC ablation is rare.

Authors+Show Affiliations

University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado.University of Colorado, Section of Cardiac Electrophysiology, Division of Cardiology, Aurora, Colorado. Electronic address: drnguyen@stanford.edu.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31648744

Citation

Edward, Justin A., et al. "Follow-Up After Catheter Ablation of Papillary Muscles and Valve Cusps." JACC. Clinical Electrophysiology, vol. 5, no. 10, 2019, pp. 1185-1196.
Edward JA, Zipse MM, Tompkins C, et al. Follow-Up After Catheter Ablation of Papillary Muscles and Valve Cusps. JACC Clin Electrophysiol. 2019;5(10):1185-1196.
Edward, J. A., Zipse, M. M., Tompkins, C., Varosy, P. D., Sandhu, A., Rosenberg, M., ... Nguyen, D. T. (2019). Follow-Up After Catheter Ablation of Papillary Muscles and Valve Cusps. JACC. Clinical Electrophysiology, 5(10), pp. 1185-1196. doi:10.1016/j.jacep.2019.07.004.
Edward JA, et al. Follow-Up After Catheter Ablation of Papillary Muscles and Valve Cusps. JACC Clin Electrophysiol. 2019;5(10):1185-1196. PubMed PMID: 31648744.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Follow-Up After Catheter Ablation of Papillary Muscles and Valve Cusps. AU - Edward,Justin A, AU - Zipse,Matthew M, AU - Tompkins,Christine, AU - Varosy,Paul D, AU - Sandhu,Amneet, AU - Rosenberg,Michael, AU - Aleong,Ryan, AU - Tzou,Wendy S, AU - Borne,Ryan T, AU - Sauer,William H, AU - Nguyen,Duy T, Y1 - 2019/08/28/ PY - 2019/01/30/received PY - 2019/07/08/revised PY - 2019/07/08/accepted PY - 2019/10/26/entrez KW - papillary muscles KW - radiofrequency ablation KW - valve cusps KW - valvular regurgitation KW - ventricular arrhythmia SP - 1185 EP - 1196 JF - JACC. Clinical electrophysiology JO - JACC Clin Electrophysiol VL - 5 IS - 10 N2 - OBJECTIVES: The goal of this study was to determine the impact of catheter ablation in the region of papillary muscles (PMs) and valvular cusps (VC) on mitral, tricuspid, or aortic valve function. BACKGROUND: Ventricular arrhythmias arising from PMs and VCs often require extensive catheter ablation. Little is known regarding the risk of valve dysfunction after radiofrequency catheter ablation of such arrhythmias. METHODS: A retrospective analysis was completed for 149 PM and VC VT/premature ventricular contraction (PVC) ablations from 2008 to 2018 at our institution. Patient and procedural details were collected for VT and PVC ablation cases involving PMs and VCs with available echocardiographic data pre-ablation and post-ablation (within 6 months). Degree of valvular regurgitation (VR) was graded from 0 (none) to 4 (severe), and significant valvular dysfunction was defined as a 2+ change in VR. RESULTS: Of 149 radiofrequency catheter ablation cases, there were 84 (56%) aortic valve cusp ablations, 60 (40%) left ventricular PM ablations, and 5 (3%) right ventricular PM ablations. There were no statistically significant differences between pre-ablation and post-ablation VR severity (p = 0.33). No patients had a 2+ grade change in VR severity when pre-ablation and post-ablation echocardiograms were compared. There were no significant sequelae requiring intervention in the post-ablation period. On follow-up of 36 ± 9 months, for those with a change in VR, the severity had improved to baseline or remained stable. CONCLUSIONS: Despite often-times extensive ablation on and around valvular networks, risk of longstanding or permanent valvular dysfunction after VT/PVC ablation is rare. SN - 2405-5018 UR - https://www.unboundmedicine.com/medline/citation/31648744/Follow-Up_After_Catheter_Ablation_of_Papillary_Muscles_and_Valve_Cusps L2 - https://linkinghub.elsevier.com/retrieve/pii/S2405-500X(19)30500-6 DB - PRIME DP - Unbound Medicine ER -