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Metabolic syndrome and lung function in Korean children and adolescents: A cross-sectional study.
Sci Rep. 2019 Oct 30; 9(1):15646.SR

Abstract

This study aimed to investigate whether obesity and metabolic syndrome (MetS) are associated with pulmonary function in Korean children and adolescents. Data from the 2009-2011 Korea National Health and Nutrition Examination Survey which is cross-sectional, nationwide, and representative survey were used. Adjusted regression analysis was performed to evaluate the association of obesity and MetS with lung function in children and adolescents. A total of 763 children and adolescents aged 10-18 years were evaluated. We found no significant difference in FEV1% predicted, FVC% predicted, and FEV1/FVC ratio among the obesity groups. Subjects with MetS showed a significantly lower FEV1 predicted (91.54 ± 0.74% vs 94.64 ± 0.73%, P = 0.004), lower FVC% predicted (91.86 ± 0.63% vs 95.20 ± 0.63%, P < 0.001), and lower FEV1/FVC ratio (76.76 ± 0.43% vs 80.13 ± 0.43%, P < 0.001) than those without MetS. Elevated waist circumference (WC), systolic blood pressure, fasting glucose, and lower high-density lipoprotein cholesterol (HDL-C) were independently associated with lower FEV1/FVC ratio (all P < 0.05, respectively). Among MetS components, increased WC was the most important factor influencing lower FEV1/FVC ratio. In conclusion, lung function in MetS patients was significantly lower, and the MetS component was independently associated.

Authors+Show Affiliations

Department of Pediatrics, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, Korea. Allergy and Clinical Immunology Research center, Hallym University College of Medicine, Chuncheon, Korea.Department of Pediatrics, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, Korea.Department of Pediatrics, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, Korea.Department of Pediatrics, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, Korea.Department of Pediatrics, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, Korea.Department of Pediatrics, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, Korea. royjays0217@hallym.or.kr.Department of Pediatrics, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Gyeonggi-do, Korea. jeonyouhoon@hallym.or.kr. Allergy and Clinical Immunology Research center, Hallym University College of Medicine, Chuncheon, Korea. jeonyouhoon@hallym.or.kr.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31666559

Citation

Kim, Minji, et al. "Metabolic Syndrome and Lung Function in Korean Children and Adolescents: a Cross-sectional Study." Scientific Reports, vol. 9, no. 1, 2019, p. 15646.
Kim M, Choi S, Choi SH, et al. Metabolic syndrome and lung function in Korean children and adolescents: A cross-sectional study. Sci Rep. 2019;9(1):15646.
Kim, M., Choi, S., Choi, S. H., Shin, S. H., Kim, S. K., Shim, Y. S., & Jeon, Y. H. (2019). Metabolic syndrome and lung function in Korean children and adolescents: A cross-sectional study. Scientific Reports, 9(1), 15646. https://doi.org/10.1038/s41598-019-51968-2
Kim M, et al. Metabolic Syndrome and Lung Function in Korean Children and Adolescents: a Cross-sectional Study. Sci Rep. 2019 Oct 30;9(1):15646. PubMed PMID: 31666559.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Metabolic syndrome and lung function in Korean children and adolescents: A cross-sectional study. AU - Kim,Minji, AU - Choi,Seoheui, AU - Choi,Soo-Han, AU - Shin,Seon-Hee, AU - Kim,Sung Koo, AU - Shim,Young Suk, AU - Jeon,You Hoon, Y1 - 2019/10/30/ PY - 2019/07/11/received PY - 2019/10/10/accepted PY - 2019/11/1/entrez PY - 2019/11/2/pubmed PY - 2020/11/11/medline SP - 15646 EP - 15646 JF - Scientific reports JO - Sci Rep VL - 9 IS - 1 N2 - This study aimed to investigate whether obesity and metabolic syndrome (MetS) are associated with pulmonary function in Korean children and adolescents. Data from the 2009-2011 Korea National Health and Nutrition Examination Survey which is cross-sectional, nationwide, and representative survey were used. Adjusted regression analysis was performed to evaluate the association of obesity and MetS with lung function in children and adolescents. A total of 763 children and adolescents aged 10-18 years were evaluated. We found no significant difference in FEV1% predicted, FVC% predicted, and FEV1/FVC ratio among the obesity groups. Subjects with MetS showed a significantly lower FEV1 predicted (91.54 ± 0.74% vs 94.64 ± 0.73%, P = 0.004), lower FVC% predicted (91.86 ± 0.63% vs 95.20 ± 0.63%, P < 0.001), and lower FEV1/FVC ratio (76.76 ± 0.43% vs 80.13 ± 0.43%, P < 0.001) than those without MetS. Elevated waist circumference (WC), systolic blood pressure, fasting glucose, and lower high-density lipoprotein cholesterol (HDL-C) were independently associated with lower FEV1/FVC ratio (all P < 0.05, respectively). Among MetS components, increased WC was the most important factor influencing lower FEV1/FVC ratio. In conclusion, lung function in MetS patients was significantly lower, and the MetS component was independently associated. SN - 2045-2322 UR - https://www.unboundmedicine.com/medline/citation/31666559/Metabolic_syndrome_and_lung_function_in_Korean_children_and_adolescents:_A_cross_sectional_study_ L2 - https://doi.org/10.1038/s41598-019-51968-2 DB - PRIME DP - Unbound Medicine ER -