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Prognostic Parameters in Differentiated Thyroid Carcinomas.
Surg Pathol Clin 2019; 12(4):883-900SP

Abstract

Differentiated thyroid carcinomas make up most thyroid malignancies. The AJCC staging system and the ATA risk prediction system are the best predictors of mortality and recurrence, respectively. Key factors to be identified and reported by pathologists are reviewed in this article and include: (1) aggressive histologic variants of papillary thyroid carcinoma (including tall cell, columnar cell, and hobnail variants); (2) presence of gross extrathyroidal extension (into skeletal muscle or adjacent organs); (3) angioinvasion (including number of foci); (4) number, anatomic level, and size of lymph node metastases; (4) extranodal extension; (5) genetics (especially BRAF V600E or TERT promoter mutation).

Authors+Show Affiliations

Department of Pathology, The University of Chicago, 5841 South Maryland Avenue, MC 6101, Chicago, IL 60637, USA. Electronic address: nicole.cipriani@uchospitals.edu.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31672296

Citation

Cipriani, Nicole A.. "Prognostic Parameters in Differentiated Thyroid Carcinomas." Surgical Pathology Clinics, vol. 12, no. 4, 2019, pp. 883-900.
Cipriani NA. Prognostic Parameters in Differentiated Thyroid Carcinomas. Surg Pathol Clin. 2019;12(4):883-900.
Cipriani, N. A. (2019). Prognostic Parameters in Differentiated Thyroid Carcinomas. Surgical Pathology Clinics, 12(4), pp. 883-900. doi:10.1016/j.path.2019.07.001.
Cipriani NA. Prognostic Parameters in Differentiated Thyroid Carcinomas. Surg Pathol Clin. 2019;12(4):883-900. PubMed PMID: 31672296.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prognostic Parameters in Differentiated Thyroid Carcinomas. A1 - Cipriani,Nicole A, Y1 - 2019/09/18/ PY - 2019/11/2/entrez PY - 2019/11/2/pubmed PY - 2019/11/2/medline KW - Angioinvasion KW - BRAF V600E KW - Extranodal extension KW - Extrathyroidal extension KW - Follicular thyroid carcinoma KW - Papillary thyroid carcinoma KW - TERT promoter KW - Variants SP - 883 EP - 900 JF - Surgical pathology clinics JO - Surg Pathol Clin VL - 12 IS - 4 N2 - Differentiated thyroid carcinomas make up most thyroid malignancies. The AJCC staging system and the ATA risk prediction system are the best predictors of mortality and recurrence, respectively. Key factors to be identified and reported by pathologists are reviewed in this article and include: (1) aggressive histologic variants of papillary thyroid carcinoma (including tall cell, columnar cell, and hobnail variants); (2) presence of gross extrathyroidal extension (into skeletal muscle or adjacent organs); (3) angioinvasion (including number of foci); (4) number, anatomic level, and size of lymph node metastases; (4) extranodal extension; (5) genetics (especially BRAF V600E or TERT promoter mutation). SN - 1875-9157 UR - https://www.unboundmedicine.com/medline/citation/31672296/Prognostic_Parameters_in_Differentiated_Thyroid_Carcinomas L2 - https://linkinghub.elsevier.com/retrieve/pii/S1875-9181(19)30054-6 DB - PRIME DP - Unbound Medicine ER -