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Zika virus: an emerging challenge to public health worldwide.
Can J Microbiol. 2020 Feb; 66(2):87-98.CJ

Abstract

Zika virus (ZIKV) is a mosquito-borne virus that was first isolated from Zika forest, Uganda, in 1947. Since its inception, major and minor outbreaks have been documented from several parts of world. Aedes spp. mosquitoes are the primary vectors of ZIKV, but the virus can also be transmitted through sexual practices, materno-fetal transmission, and blood transfusion. The clinical presentations of symptomatic ZIKV infections are similar to dengue and chikungunya, including fever, headache, arthralgia, retro-orbital pain, conjunctivitis, and rash. ZIKV often causes mild illness in the majority of cases, but in some instances, it is linked with congenital microcephaly and autoimmune disorders like Guillain-Barré syndrome. The recent Indian ZIKV outbreak suggests that the virus is circulating in the South East Asian region and may cause new outbreaks in future. At present, no specific vaccines or antivirals are available to treat ZIKV, so management and control of ZIKV infections rely mostly on preventive measures.

Authors+Show Affiliations

Centre for Biotechnology, Maharshi Dayanand University, Rohtak-124001, Haryana, India.Department of Biotechnology, Himachal Pradesh University, Shimla-171005, Himachal Pradesh, India.Centre for Biotechnology, Maharshi Dayanand University, Rohtak-124001, Haryana, India.Centre for Biotechnology, Maharshi Dayanand University, Rohtak-124001, Haryana, India.Department of Genetics, Maharshi Dayanand University, Rohtak-124001, Haryana, India.Centre for Biotechnology, Maharshi Dayanand University, Rohtak-124001, Haryana, India.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

31682478

Citation

Sharma, Vikrant, et al. "Zika Virus: an Emerging Challenge to Public Health Worldwide." Canadian Journal of Microbiology, vol. 66, no. 2, 2020, pp. 87-98.
Sharma V, Sharma M, Dhull D, et al. Zika virus: an emerging challenge to public health worldwide. Can J Microbiol. 2020;66(2):87-98.
Sharma, V., Sharma, M., Dhull, D., Sharma, Y., Kaushik, S., & Kaushik, S. (2020). Zika virus: an emerging challenge to public health worldwide. Canadian Journal of Microbiology, 66(2), 87-98. https://doi.org/10.1139/cjm-2019-0331
Sharma V, et al. Zika Virus: an Emerging Challenge to Public Health Worldwide. Can J Microbiol. 2020;66(2):87-98. PubMed PMID: 31682478.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zika virus: an emerging challenge to public health worldwide. AU - Sharma,Vikrant, AU - Sharma,Manisha, AU - Dhull,Divya, AU - Sharma,Yashika, AU - Kaushik,Sulochana, AU - Kaushik,Samander, Y1 - 2019/11/04/ PY - 2019/11/5/pubmed PY - 2020/4/24/medline PY - 2019/11/5/entrez KW - ZIKV KW - Zika virus KW - emerging infection KW - flavivirus KW - flaviviruses KW - infection émergente KW - microcephaly KW - microcéphalie KW - virus Zika SP - 87 EP - 98 JF - Canadian journal of microbiology JO - Can. J. Microbiol. VL - 66 IS - 2 N2 - Zika virus (ZIKV) is a mosquito-borne virus that was first isolated from Zika forest, Uganda, in 1947. Since its inception, major and minor outbreaks have been documented from several parts of world. Aedes spp. mosquitoes are the primary vectors of ZIKV, but the virus can also be transmitted through sexual practices, materno-fetal transmission, and blood transfusion. The clinical presentations of symptomatic ZIKV infections are similar to dengue and chikungunya, including fever, headache, arthralgia, retro-orbital pain, conjunctivitis, and rash. ZIKV often causes mild illness in the majority of cases, but in some instances, it is linked with congenital microcephaly and autoimmune disorders like Guillain-Barré syndrome. The recent Indian ZIKV outbreak suggests that the virus is circulating in the South East Asian region and may cause new outbreaks in future. At present, no specific vaccines or antivirals are available to treat ZIKV, so management and control of ZIKV infections rely mostly on preventive measures. SN - 1480-3275 UR - https://www.unboundmedicine.com/medline/citation/31682478/Zika_virus:_an_emerging_challenge_to_public_health_worldwide_ L2 - http://www.nrcresearchpress.com/doi/full/10.1139/cjm-2019-0331?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -