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Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke.
J Prev Alzheimers Dis. 2019; 6(4):267-273.JP

Abstract

OBJECTIVE

This study sought to determine if the MIND diet (a hybrid of the Mediterranean and Dash diets, with modifications based on the science of nutrition and the brain), is effective in preventing cognitive decline after stroke.

DESIGN

We analyzed 106 participants of a community cohort study who had completed a diet assessment and two or more annual cognitive assessments and who also had a clinical history of stroke. Cognition in five cognitive domains was assessed using structured clinical evaluations that included a battery of 19 cognitive tests. MIND diet scores were computed using a valid food frequency questionnaire (FFQ). Dietary components of the MIND diet included whole grains, leafy greens and other vegetables, berries, beans, nuts, lean meats, fish, poultry, and olive oil and reduced consumption of cheese, butter, fried foods, and sweets. MIND diet scores were modeled in tertiles. The influence of baseline MIND score on change in a global cognitive function measure and in the five cognitive domains was assessed using linear mixed models adjusted for age and other potential confounders.

RESULTS

With adjustment for age, sex, education, APOE-ε4, caloric intake, smoking, and participation in cognitive and physical activities, the top vs lowest tertiles of MIND diet scores had a slower rate of global cognitive decline (β = .08; CI = 0.0074, 0.156) over an average of 5.9 years of follow-up.

CONCLUSIONS

High adherence to the MIND diet was associated with a slower rate of cognitive decline after stroke.

Authors+Show Affiliations

Laurel Cherian, Rush University Medical Center, Chicago, IL USA, laurel_j_cherian@rush.edu.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

31686099

Citation

Cherian, L, et al. "Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke." The Journal of Prevention of Alzheimer's Disease, vol. 6, no. 4, 2019, pp. 267-273.
Cherian L, Wang Y, Fakuda K, et al. Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke. J Prev Alzheimers Dis. 2019;6(4):267-273.
Cherian, L., Wang, Y., Fakuda, K., Leurgans, S., Aggarwal, N., & Morris, M. (2019). Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke. The Journal of Prevention of Alzheimer's Disease, 6(4), 267-273. https://doi.org/10.14283/jpad.2019.28
Cherian L, et al. Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke. J Prev Alzheimers Dis. 2019;6(4):267-273. PubMed PMID: 31686099.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mediterranean-Dash Intervention for Neurodegenerative Delay (MIND) Diet Slows Cognitive Decline After Stroke. AU - Cherian,L, AU - Wang,Y, AU - Fakuda,K, AU - Leurgans,S, AU - Aggarwal,N, AU - Morris,M, PY - 2019/11/6/entrez PY - 2019/11/7/pubmed PY - 2020/7/25/medline KW - Stroke KW - cognitive decline KW - diet KW - nutrition KW - prevention SP - 267 EP - 273 JF - The journal of prevention of Alzheimer's disease JO - J Prev Alzheimers Dis VL - 6 IS - 4 N2 - OBJECTIVE: This study sought to determine if the MIND diet (a hybrid of the Mediterranean and Dash diets, with modifications based on the science of nutrition and the brain), is effective in preventing cognitive decline after stroke. DESIGN: We analyzed 106 participants of a community cohort study who had completed a diet assessment and two or more annual cognitive assessments and who also had a clinical history of stroke. Cognition in five cognitive domains was assessed using structured clinical evaluations that included a battery of 19 cognitive tests. MIND diet scores were computed using a valid food frequency questionnaire (FFQ). Dietary components of the MIND diet included whole grains, leafy greens and other vegetables, berries, beans, nuts, lean meats, fish, poultry, and olive oil and reduced consumption of cheese, butter, fried foods, and sweets. MIND diet scores were modeled in tertiles. The influence of baseline MIND score on change in a global cognitive function measure and in the five cognitive domains was assessed using linear mixed models adjusted for age and other potential confounders. RESULTS: With adjustment for age, sex, education, APOE-ε4, caloric intake, smoking, and participation in cognitive and physical activities, the top vs lowest tertiles of MIND diet scores had a slower rate of global cognitive decline (β = .08; CI = 0.0074, 0.156) over an average of 5.9 years of follow-up. CONCLUSIONS: High adherence to the MIND diet was associated with a slower rate of cognitive decline after stroke. SN - 2426-0266 UR - https://www.unboundmedicine.com/medline/citation/31686099/Mediterranean_Dash_Intervention_for_Neurodegenerative_Delay__MIND__Diet_Slows_Cognitive_Decline_After_Stroke_ L2 - https://doi.org/10.14283/jpad.2019.28 DB - PRIME DP - Unbound Medicine ER -