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Catheter-induced premature ventricular complexes (PVCs) may aid in the determination of optimal timing for clinical PVC ablation.
Pacing Clin Electrophysiol 2019; 42(12):1573-1578PC

Abstract

BACKGROUND

The aim of the present study is to evaluate whether catheter-induced premature ventricular complexes (PVCs) produced at the presumptive ablation site may aid in the identification of the optimal timing of the earliest local activation for the successful ablation of clinical PVCs.

METHODS

Sixty-three consecutive patients (35 males, age: 53.5 ± 14.4 years) without any exclusion criteria who had undergone PVC ablation between 1 July 2018 and 1 July 2019 constituted our study population. The time interval between the beginning of the EGM and the beginning of the QRS of each catheter-induced PVC (Cath EGM-ECG) and the time interval between the beginning of the EGM of clinical PVCs at the earliest site and the beginning of the QRS of clinical PVCs (PVC earliest EGM-ECG) were noted for each patient. The value of Cath EGM-ECG as a reference for procedural success of ablation was evaluated by examining the relationship between Cath EGM-ECG and PVC earliest EGM-ECG.

RESULTS

Fifty-two patients had successful ablation, and 43 of them (82.7%) had PVC earliest EGM-ECG values greater than or equal to Cath EGM-ECG. Eleven patients had procedural failure, and all of them had PVC earliest EGM-ECG values lower than Cath EGM-ECG. A PVC earliest EGM-ECG value -1.5 ms greater than Cath EGM-ECG predicted successful ablation with a sensitivity of 90.4% and a specificity of 100.0% in the general patient population.

CONCLUSION

Cath EGM-ECG seems to serve as a reliable guide for finding the optimal timing of the earliest site for successful PVC ablation.

Authors+Show Affiliations

Department of Cardiology, University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey.Department of Cardiology, University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey.Department of Cardiology, University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey.Department of Cardiology, University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey.Department of Cardiology, University of Health Sciences, Kartal Kosuyolu Training and Research Hospital, Istanbul, Turkey.Cardiology Clinic, Mardin State Hospital, Mardin, Turkey.Department of Cardiology, Marmara University School of Medicine, Istanbul, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31696518

Citation

Demir, Serdar, et al. "Catheter-induced Premature Ventricular Complexes (PVCs) May Aid in the Determination of Optimal Timing for Clinical PVC Ablation." Pacing and Clinical Electrophysiology : PACE, vol. 42, no. 12, 2019, pp. 1573-1578.
Demir S, Akgun T, Gulsen K, et al. Catheter-induced premature ventricular complexes (PVCs) may aid in the determination of optimal timing for clinical PVC ablation. Pacing Clin Electrophysiol. 2019;42(12):1573-1578.
Demir, S., Akgun, T., Gulsen, K., Kup, A., Uslu, A., Kayan, F., & Kepez, A. (2019). Catheter-induced premature ventricular complexes (PVCs) may aid in the determination of optimal timing for clinical PVC ablation. Pacing and Clinical Electrophysiology : PACE, 42(12), pp. 1573-1578. doi:10.1111/pace.13833.
Demir S, et al. Catheter-induced Premature Ventricular Complexes (PVCs) May Aid in the Determination of Optimal Timing for Clinical PVC Ablation. Pacing Clin Electrophysiol. 2019;42(12):1573-1578. PubMed PMID: 31696518.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Catheter-induced premature ventricular complexes (PVCs) may aid in the determination of optimal timing for clinical PVC ablation. AU - Demir,Serdar, AU - Akgun,Taylan, AU - Gulsen,Kamil, AU - Kup,Ayhan, AU - Uslu,Abdulkadir, AU - Kayan,Fethullah, AU - Kepez,Alper, Y1 - 2019/11/17/ PY - 2019/08/11/received PY - 2019/10/16/revised PY - 2019/11/02/accepted PY - 2019/11/7/pubmed PY - 2019/11/7/medline PY - 2019/11/8/entrez KW - activation mapping KW - premature ventricular complex KW - radiofrequency ablation SP - 1573 EP - 1578 JF - Pacing and clinical electrophysiology : PACE JO - Pacing Clin Electrophysiol VL - 42 IS - 12 N2 - BACKGROUND: The aim of the present study is to evaluate whether catheter-induced premature ventricular complexes (PVCs) produced at the presumptive ablation site may aid in the identification of the optimal timing of the earliest local activation for the successful ablation of clinical PVCs. METHODS: Sixty-three consecutive patients (35 males, age: 53.5 ± 14.4 years) without any exclusion criteria who had undergone PVC ablation between 1 July 2018 and 1 July 2019 constituted our study population. The time interval between the beginning of the EGM and the beginning of the QRS of each catheter-induced PVC (Cath EGM-ECG) and the time interval between the beginning of the EGM of clinical PVCs at the earliest site and the beginning of the QRS of clinical PVCs (PVC earliest EGM-ECG) were noted for each patient. The value of Cath EGM-ECG as a reference for procedural success of ablation was evaluated by examining the relationship between Cath EGM-ECG and PVC earliest EGM-ECG. RESULTS: Fifty-two patients had successful ablation, and 43 of them (82.7%) had PVC earliest EGM-ECG values greater than or equal to Cath EGM-ECG. Eleven patients had procedural failure, and all of them had PVC earliest EGM-ECG values lower than Cath EGM-ECG. A PVC earliest EGM-ECG value -1.5 ms greater than Cath EGM-ECG predicted successful ablation with a sensitivity of 90.4% and a specificity of 100.0% in the general patient population. CONCLUSION: Cath EGM-ECG seems to serve as a reliable guide for finding the optimal timing of the earliest site for successful PVC ablation. SN - 1540-8159 UR - https://www.unboundmedicine.com/medline/citation/31696518/Catheter-induced_premature_ventricular_complexes_(PVCs)_may_aid_in_the_determination_of_optimal_timing_for_clinical_PVC_ablation L2 - https://doi.org/10.1111/pace.13833 DB - PRIME DP - Unbound Medicine ER -