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Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study.
J Occup Environ Med 2020; 62(1):e1-e6JO

Abstract

OBJECTIVE

To evaluate mortality patterns among participants in a community-based screening program for asbestos-related disease.

METHODS

We calculated standardized mortality ratios (SMRs) and stratified results by exposure group (three occupational exposure groups, household contacts and residents without occupational asbestos exposure) and by radiographic abnormality presence.

RESULTS

All-cause mortality (15.8%; 1,429/8,043) was statistically lower than expected. Asbestosis was statistically elevated in all exposure groups. Lung cancer was moderately associated with vermiculite miner/miller employment. Mesothelioma was elevated in that same exposure group and among residents. Systemic autoimmune disease mortality was also elevated. Radiographic parenchymal abnormalities were associated with lung cancer mortality.

CONCLUSION

In addition to asbestos-related mortality in occupational exposure groups, this initial follow-up of this cohort also shows elevated mortality for some asbestos-related causes in non-occupational exposure groups.

Authors+Show Affiliations

Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia (Mr Larson); Montana Department of Public Health and Human Services, Helena, Montana (Ms Williamson); Hospital for Special Surgery, New York, New York (Dr Antao).No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31714372

Citation

Larson, Theodore C., et al. "Follow-Up of the Libby, Montana Screening Cohort: a 17-Year Mortality Study." Journal of Occupational and Environmental Medicine, vol. 62, no. 1, 2020, pp. e1-e6.
Larson TC, Williamson L, Antao VC. Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study. J Occup Environ Med. 2020;62(1):e1-e6.
Larson, T. C., Williamson, L., & Antao, V. C. (2020). Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study. Journal of Occupational and Environmental Medicine, 62(1), pp. e1-e6. doi:10.1097/JOM.0000000000001760.
Larson TC, Williamson L, Antao VC. Follow-Up of the Libby, Montana Screening Cohort: a 17-Year Mortality Study. J Occup Environ Med. 2020;62(1):e1-e6. PubMed PMID: 31714372.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study. AU - Larson,Theodore C, AU - Williamson,Laura, AU - Antao,Vinicius C, PY - 2019/11/13/pubmed PY - 2019/11/13/medline PY - 2019/11/13/entrez SP - e1 EP - e6 JF - Journal of occupational and environmental medicine JO - J. Occup. Environ. Med. VL - 62 IS - 1 N2 - OBJECTIVE: To evaluate mortality patterns among participants in a community-based screening program for asbestos-related disease. METHODS: We calculated standardized mortality ratios (SMRs) and stratified results by exposure group (three occupational exposure groups, household contacts and residents without occupational asbestos exposure) and by radiographic abnormality presence. RESULTS: All-cause mortality (15.8%; 1,429/8,043) was statistically lower than expected. Asbestosis was statistically elevated in all exposure groups. Lung cancer was moderately associated with vermiculite miner/miller employment. Mesothelioma was elevated in that same exposure group and among residents. Systemic autoimmune disease mortality was also elevated. Radiographic parenchymal abnormalities were associated with lung cancer mortality. CONCLUSION: In addition to asbestos-related mortality in occupational exposure groups, this initial follow-up of this cohort also shows elevated mortality for some asbestos-related causes in non-occupational exposure groups. SN - 1536-5948 UR - https://www.unboundmedicine.com/medline/citation/31714372/Follow-Up_of_the_Libby,_Montana_Screening_Cohort:_A_17-Year_Mortality_Study L2 - http://dx.doi.org/10.1097/JOM.0000000000001760 DB - PRIME DP - Unbound Medicine ER -