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Effects of postpartum depression on the behaviour of children born to mothers with epilepsy.
Seizure 2019; 73:31-38S

Abstract

PURPOSE

Postpartum depression (PPD) is a non-psychotic depressive disorder that begins within 4 weeks of childbirth. This study aimed to evaluate the prevalence of PPD by screening mothers with the Edinburgh Postnatal Depression Scale (EPDS), to assess the behavioural outcome of children born to mothers with and without epilepsy and to investigate the relationship between PPD and children's behavioural problems.

METHOD

We enrolled 80 pregnancies of women with epilepsy, who filled in EPDS after birth, and afterward we asked them to complete the Child Behavior Checklist (CBCL).

RESULTS

23.8% of patients presented PPD. Children, when the CBCL were completed, had a mean age of 6.05 ± 3.07 years. The CBCL results indicate the occurrence of at least one behavioural issue in 25.0% (20/80) of children. CBCL scores revealed a higher prevalence of behavioural disturbances with regards to the CBCL Total (P = 0.016), internalizing (P = 0.014) and somatic problems (P = 0.048) in patients with PPD vs. patients without PPD. We found an association between mothers' EPDS total score and children's CBCL global score (P = 0.034), internalizing score (P = 0.021), anxiety problems (P = 0.05), affective problems (P = 0.027) and withdrawn/depressed (P = 0.05). We recorded a statistically higher malformation rate in patients with PPD (P = 0.005) compared to the general population.

CONCLUSIONS

Children born from mothers with epilepsy have an increased risk for emotional disorders. These findings highlight the importance of screening for emotional distress and providing adequate interventions to children born to women with epilepsy.

Authors+Show Affiliations

Epilepsy Center-Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, San Paolo Hospital, Milan, Italy. Electronic address: katherine.turner@asst-santipaolocarlo.it.Epilepsy Center-Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, San Paolo Hospital, Milan, Italy.Epilepsy Center-Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, San Paolo Hospital, Milan, Italy.Epilepsy Center-Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, San Paolo Hospital, Milan, Italy; Department of Health Sciences, University of Milan, Italy.Epilepsy Center-Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, San Paolo Hospital, Milan, Italy.Epilepsy Center-Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, San Paolo Hospital, Milan, Italy.Epilepsy Center-Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, San Paolo Hospital, Milan, Italy.Epilepsy Center-Child Neuropsychiatry Unit, ASST Santi Paolo Carlo, San Paolo Hospital, Milan, Italy; Department of Health Sciences, University of Milan, Italy.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31715519

Citation

Turner, Katherine, et al. "Effects of Postpartum Depression On the Behaviour of Children Born to Mothers With Epilepsy." Seizure, vol. 73, 2019, pp. 31-38.
Turner K, Zambrelli E, Bassanese G, et al. Effects of postpartum depression on the behaviour of children born to mothers with epilepsy. Seizure. 2019;73:31-38.
Turner, K., Zambrelli, E., Bassanese, G., Vignoli, A., Valvassori Bolgè, M., Baldi, C., ... Canevini, M. P. (2019). Effects of postpartum depression on the behaviour of children born to mothers with epilepsy. Seizure, 73, pp. 31-38. doi:10.1016/j.seizure.2019.10.018.
Turner K, et al. Effects of Postpartum Depression On the Behaviour of Children Born to Mothers With Epilepsy. Seizure. 2019;73:31-38. PubMed PMID: 31715519.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of postpartum depression on the behaviour of children born to mothers with epilepsy. AU - Turner,Katherine, AU - Zambrelli,Elena, AU - Bassanese,Giulia, AU - Vignoli,Aglaia, AU - Valvassori Bolgè,Maria, AU - Baldi,Cristina, AU - Franza,Albertina, AU - Canevini,Maria Paola, Y1 - 2019/10/31/ PY - 2019/01/05/received PY - 2019/10/19/revised PY - 2019/10/23/accepted PY - 2019/11/13/pubmed PY - 2019/11/13/medline PY - 2019/11/13/entrez KW - AEDs exposure KW - Behavioural development KW - EPDS KW - Postpartum depression SP - 31 EP - 38 JF - Seizure JO - Seizure VL - 73 N2 - PURPOSE: Postpartum depression (PPD) is a non-psychotic depressive disorder that begins within 4 weeks of childbirth. This study aimed to evaluate the prevalence of PPD by screening mothers with the Edinburgh Postnatal Depression Scale (EPDS), to assess the behavioural outcome of children born to mothers with and without epilepsy and to investigate the relationship between PPD and children's behavioural problems. METHOD: We enrolled 80 pregnancies of women with epilepsy, who filled in EPDS after birth, and afterward we asked them to complete the Child Behavior Checklist (CBCL). RESULTS: 23.8% of patients presented PPD. Children, when the CBCL were completed, had a mean age of 6.05 ± 3.07 years. The CBCL results indicate the occurrence of at least one behavioural issue in 25.0% (20/80) of children. CBCL scores revealed a higher prevalence of behavioural disturbances with regards to the CBCL Total (P = 0.016), internalizing (P = 0.014) and somatic problems (P = 0.048) in patients with PPD vs. patients without PPD. We found an association between mothers' EPDS total score and children's CBCL global score (P = 0.034), internalizing score (P = 0.021), anxiety problems (P = 0.05), affective problems (P = 0.027) and withdrawn/depressed (P = 0.05). We recorded a statistically higher malformation rate in patients with PPD (P = 0.005) compared to the general population. CONCLUSIONS: Children born from mothers with epilepsy have an increased risk for emotional disorders. These findings highlight the importance of screening for emotional distress and providing adequate interventions to children born to women with epilepsy. SN - 1532-2688 UR - https://www.unboundmedicine.com/medline/citation/31715519/Effects_of_postpartum_depression_on_the_behaviour_of_children_born_to_mothers_with_epilepsy L2 - https://linkinghub.elsevier.com/retrieve/pii/S1059-1311(19)30016-0 DB - PRIME DP - Unbound Medicine ER -