Tags

Type your tag names separated by a space and hit enter

Necrobiosis lipoidica in a Nigerian woman - Report of a case.
Niger J Clin Pract. 2019 Nov; 22(11):1626-1628.NJ

Abstract

Necrobiosis lipoidica (NL), one of a group of "necrobiotic" granulomatous cutaneous disorders, is characterized histologically by layers of poorly defined, horizontally oriented, altered "necrobiotic" collagen surrounded by, and alternating with, layers of chronic inflammatory cells, histiocytes, and giant cells throughout the full thickness of the dermis. It is a rare disease associated mostly with diabetes mellitus in whom it may affect 0.3%-1.2% although it has also been associated with other cutaneous and systemic disorders and may occur in otherwise normal people. NL has been reported from all over the world, but there appears to be very few reports of NL in Black Africans. We report the case of a 55-year-old diabetic Nigerian woman who presented with typical NL lesions on the lower legs and who responded very well to topical betamethasone dipropionate 0.05% cream. We also briefly review the probable underlying mechanisms leading to the condition and the various treatments that have been found useful.

Authors+Show Affiliations

Dermatology Unit, Department of Medicine, Kaduna State University/Barau Dikko Teaching Hospital, Kaduna, Nigeria.

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

31719288

Citation

Yahya, H. "Necrobiosis Lipoidica in a Nigerian Woman - Report of a Case." Nigerian Journal of Clinical Practice, vol. 22, no. 11, 2019, pp. 1626-1628.
Yahya H. Necrobiosis lipoidica in a Nigerian woman - Report of a case. Niger J Clin Pract. 2019;22(11):1626-1628.
Yahya, H. (2019). Necrobiosis lipoidica in a Nigerian woman - Report of a case. Nigerian Journal of Clinical Practice, 22(11), 1626-1628. https://doi.org/10.4103/njcp.njcp_40_19
Yahya H. Necrobiosis Lipoidica in a Nigerian Woman - Report of a Case. Niger J Clin Pract. 2019;22(11):1626-1628. PubMed PMID: 31719288.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Necrobiosis lipoidica in a Nigerian woman - Report of a case. A1 - Yahya,H, PY - 2019/11/14/entrez PY - 2019/11/14/pubmed PY - 2019/11/14/medline KW - Black Africans KW - Nigerian woman KW - diabetes KW - necrobiosis lipoidica KW - necrobiosis lipoidica diabeticorum SP - 1626 EP - 1628 JF - Nigerian journal of clinical practice JO - Niger J Clin Pract VL - 22 IS - 11 N2 - Necrobiosis lipoidica (NL), one of a group of "necrobiotic" granulomatous cutaneous disorders, is characterized histologically by layers of poorly defined, horizontally oriented, altered "necrobiotic" collagen surrounded by, and alternating with, layers of chronic inflammatory cells, histiocytes, and giant cells throughout the full thickness of the dermis. It is a rare disease associated mostly with diabetes mellitus in whom it may affect 0.3%-1.2% although it has also been associated with other cutaneous and systemic disorders and may occur in otherwise normal people. NL has been reported from all over the world, but there appears to be very few reports of NL in Black Africans. We report the case of a 55-year-old diabetic Nigerian woman who presented with typical NL lesions on the lower legs and who responded very well to topical betamethasone dipropionate 0.05% cream. We also briefly review the probable underlying mechanisms leading to the condition and the various treatments that have been found useful. SN - 1119-3077 UR - https://www.unboundmedicine.com/medline/citation/31719288/Necrobiosis_lipoidica_in_a_Nigerian_woman___Report_of_a_case_ L2 - http://www.njcponline.com/article.asp?issn=1119-3077;year=2019;volume=22;issue=11;spage=1626;epage=1628;aulast=Yahya DB - PRIME DP - Unbound Medicine ER -