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Myocardial preservation methods in isolated minimal invasive mitral valve surgery: Society of Thoracic Surgeons (STS) database outcomes.

Abstract

OBJECTIVE

Minimal invasive mitral valve surgery (MIMVS) has become a commonly used approach for mitral valve surgery. Several techniques of myocardial preservation were described in patients undergoing MIMVS. We aim to evaluate preservation technique and short term outcomes.

METHODS

A retrospective analysis of patients who underwent isolated MIMVS and were included in the Society of Thoracic Surgeons (STS) database.

RESULTS

The final cohort included 4976 patients. Mean age was 63.1 years (SD, 12.5) and 42.6% were females. Antegrade delivery method (71.3% of the patients) was the most common, follow by antergrade/retrograde (19.9%). Blood, crystalloid solution, and combination of blood-crystalloid were used in 62.4%, 13.2%, and 13.7%, respectively. In multivariate analysis, cardioplegia technique was associated with mortality (P = .011), pleural effusion (P = .045), and length of ICU stay (P < .001). Antegrade-crystalloid (OR, 3.37; 95%CI, 1.70-6.68) and antegrade/retrograde-blood/crystalloid (OR, 3.28; 95%CI, 1.15-9.38) were associated with increased risk for mortality compared with antegrade-blood cardioplegia. Data on postoperative ejection fraction (EF), CPK-MB, and Troponin was available only in 30%, 9%, and 5% of the patients, respectively, and were not included in the analysis.

CONCLUSIONS

Ante-grade-blood was the most common preservation technique in MIMVS. Ante-grade-crystalloid and ante-grade/retrograde-blood/crystalloid are associated with increased risk for mortality. The results suggest that using crystalloid solutions for cardioplegia should be carefully considered. The STS database as a source for MIMVS outcome analysis is lacking, both in detailed specification of different surgical technique aspects, and in actual data collection of already existing categories.

Authors+Show Affiliations

Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Cardiovascular Center, Cape Cod Hospital, Hyannis, Massachusetts, USA.Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Cardiovascular Center, Cape Cod Hospital, Hyannis, Massachusetts, USA.Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Cardiovascular Center, Cape Cod Hospital, Hyannis, Massachusetts, USA.Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Cardiovascular Center, Cape Cod Hospital, Hyannis, Massachusetts, USA.School of Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.School of Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31733079

Citation

Loberman, Dan, et al. "Myocardial Preservation Methods in Isolated Minimal Invasive Mitral Valve Surgery: Society of Thoracic Surgeons (STS) Database Outcomes." Journal of Cardiac Surgery, 2019.
Loberman D, Pelletier MP, Yazdchi F, et al. Myocardial preservation methods in isolated minimal invasive mitral valve surgery: Society of Thoracic Surgeons (STS) database outcomes. J Card Surg. 2019.
Loberman, D., Pelletier, M. P., Yazdchi, F., Aranki, S. F., Preisler, Y., Mohr, R., & Ziv-Baran, T. (2019). Myocardial preservation methods in isolated minimal invasive mitral valve surgery: Society of Thoracic Surgeons (STS) database outcomes. Journal of Cardiac Surgery, doi:10.1111/jocs.14351.
Loberman D, et al. Myocardial Preservation Methods in Isolated Minimal Invasive Mitral Valve Surgery: Society of Thoracic Surgeons (STS) Database Outcomes. J Card Surg. 2019 Nov 16; PubMed PMID: 31733079.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Myocardial preservation methods in isolated minimal invasive mitral valve surgery: Society of Thoracic Surgeons (STS) database outcomes. AU - Loberman,Dan, AU - Pelletier,Marc P, AU - Yazdchi,Farchang, AU - Aranki,Sary F, AU - Preisler,Yoav, AU - Mohr,Rephael, AU - Ziv-Baran,Tomer, Y1 - 2019/11/16/ PY - 2019/11/17/pubmed PY - 2019/11/17/medline PY - 2019/11/17/entrez KW - Del Nido cardioplegia KW - minimal invasive KW - mitral valve KW - myocardial preservation JF - Journal of cardiac surgery JO - J Card Surg N2 - OBJECTIVE: Minimal invasive mitral valve surgery (MIMVS) has become a commonly used approach for mitral valve surgery. Several techniques of myocardial preservation were described in patients undergoing MIMVS. We aim to evaluate preservation technique and short term outcomes. METHODS: A retrospective analysis of patients who underwent isolated MIMVS and were included in the Society of Thoracic Surgeons (STS) database. RESULTS: The final cohort included 4976 patients. Mean age was 63.1 years (SD, 12.5) and 42.6% were females. Antegrade delivery method (71.3% of the patients) was the most common, follow by antergrade/retrograde (19.9%). Blood, crystalloid solution, and combination of blood-crystalloid were used in 62.4%, 13.2%, and 13.7%, respectively. In multivariate analysis, cardioplegia technique was associated with mortality (P = .011), pleural effusion (P = .045), and length of ICU stay (P < .001). Antegrade-crystalloid (OR, 3.37; 95%CI, 1.70-6.68) and antegrade/retrograde-blood/crystalloid (OR, 3.28; 95%CI, 1.15-9.38) were associated with increased risk for mortality compared with antegrade-blood cardioplegia. Data on postoperative ejection fraction (EF), CPK-MB, and Troponin was available only in 30%, 9%, and 5% of the patients, respectively, and were not included in the analysis. CONCLUSIONS: Ante-grade-blood was the most common preservation technique in MIMVS. Ante-grade-crystalloid and ante-grade/retrograde-blood/crystalloid are associated with increased risk for mortality. The results suggest that using crystalloid solutions for cardioplegia should be carefully considered. The STS database as a source for MIMVS outcome analysis is lacking, both in detailed specification of different surgical technique aspects, and in actual data collection of already existing categories. SN - 1540-8191 UR - https://www.unboundmedicine.com/medline/citation/31733079/Myocardial_preservation_methods_in_isolated_minimal_invasive_mitral_valve_surgery:_Society_of_Thoracic_Surgeons_(STS)_database_outcomes L2 - https://doi.org/10.1111/jocs.14351 DB - PRIME DP - Unbound Medicine ER -