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Magnesium ion activity in the mammalian endolymph measured with ion-selective microelectrodes.
Arch Otorhinolaryngol. 1988; 245(3):142-4.AO

Abstract

The free Mg++ concentration in endolymph was measured with Mg++-selective microelectrodes based on the neutral ligand ETH 1117. The property of Mg++ microelectrodes was obtained from calibration solutions, containing various Mg++ concentrations with the background electrolytes resembling endolymph. The range between 10 and 0.1 mM Mg++ concentrations changed the potentials of Mg++ microelectrodes by 14.4 +/- 3.0 mV. The endocochlear potential and the Mg++ concentration in the endolymph were 82.0 +/- 5.0 mV and 0.77 +/- 0.29 mM in the guinea pig, and 84.4 +/- 4.9 mV and 1.12 +/- 0.24 mM in the chinchilla, respectively. These results are discussed in the light of the dependence of Na+, K+-ATPase and its interaction with Ca++.

Authors+Show Affiliations

Department of Otolaryngology, University of Minnesota Medical School, Minneapolis 55414.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

3178561

Citation

Ikeda, K, et al. "Magnesium Ion Activity in the Mammalian Endolymph Measured With Ion-selective Microelectrodes." Archives of Oto-rhino-laryngology, vol. 245, no. 3, 1988, pp. 142-4.
Ikeda K, Morizono T, Kusakari J, et al. Magnesium ion activity in the mammalian endolymph measured with ion-selective microelectrodes. Arch Otorhinolaryngol. 1988;245(3):142-4.
Ikeda, K., Morizono, T., Kusakari, J., & Takasaka, T. (1988). Magnesium ion activity in the mammalian endolymph measured with ion-selective microelectrodes. Archives of Oto-rhino-laryngology, 245(3), 142-4.
Ikeda K, et al. Magnesium Ion Activity in the Mammalian Endolymph Measured With Ion-selective Microelectrodes. Arch Otorhinolaryngol. 1988;245(3):142-4. PubMed PMID: 3178561.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Magnesium ion activity in the mammalian endolymph measured with ion-selective microelectrodes. AU - Ikeda,K, AU - Morizono,T, AU - Kusakari,J, AU - Takasaka,T, PY - 1988/1/1/pubmed PY - 1988/1/1/medline PY - 1988/1/1/entrez SP - 142 EP - 4 JF - Archives of oto-rhino-laryngology JO - Arch Otorhinolaryngol VL - 245 IS - 3 N2 - The free Mg++ concentration in endolymph was measured with Mg++-selective microelectrodes based on the neutral ligand ETH 1117. The property of Mg++ microelectrodes was obtained from calibration solutions, containing various Mg++ concentrations with the background electrolytes resembling endolymph. The range between 10 and 0.1 mM Mg++ concentrations changed the potentials of Mg++ microelectrodes by 14.4 +/- 3.0 mV. The endocochlear potential and the Mg++ concentration in the endolymph were 82.0 +/- 5.0 mV and 0.77 +/- 0.29 mM in the guinea pig, and 84.4 +/- 4.9 mV and 1.12 +/- 0.24 mM in the chinchilla, respectively. These results are discussed in the light of the dependence of Na+, K+-ATPase and its interaction with Ca++. SN - 0302-9530 UR - https://www.unboundmedicine.com/medline/citation/3178561/Magnesium_ion_activity_in_the_mammalian_endolymph_measured_with_ion_selective_microelectrodes_ DB - PRIME DP - Unbound Medicine ER -