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Echocardiographic assessment of right heart size and function in dogs with pulmonary valve stenosis.
J Vet Cardiol 2019; 26:19-28JV

Abstract

INTRODUCTION/OBJECTIVES

We sought to determine the prevalence and clinical significance of right heart remodeling and right ventricular (RV) dysfunction in dogs with pulmonary valve stenosis (PS). We also sought to evaluate repeatability of several measurements of severity of PS, right heart size, and RV function in dogs with PS.

ANIMALS, MATERIALS AND METHODS

Several indices of right atrial (RA) size and RV size and function were prospectively evaluated in 48 dogs with PS. Regression analysis was used to determine if indices of right heart size and function were independently associated with maximum transpulmonary pressure gradient (max PG) and adverse clinical findings (exercise intolerance, syncope, or right heart failure). Eight dogs underwent a second echocardiogram performed by the same operator to assess repeatability of the echocardiographic indices, which was quantified by coefficient of variation (CV) and repeatability coefficient.

RESULTS

Increased RA size (81%), increased RV wall thickness (83%), and decreased tricuspid annular plane systolic excursion (TAPSE [81%]) were common. Right atrial size, end-diastolic RV area, and RV wall thickness were independently associated with max PG. Decreased TAPSE was independently associated with adverse clinical findings. All indices except RA area (18.6%) and RV systolic velocity (20.7%) had CVs <15%. Repeatability coefficients are available to help distinguish a true change versus measurement variability during serially obtained exams.

CONCLUSIONS

Right heart remodeling and RV dysfunction are common in dogs with PS and are associated with echocardiographic and clinical severity. Results support the quantitative assessment of right heart size and function in dogs with PS.

Authors+Show Affiliations

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Ave, Davis, CA, 95616, USA. Electronic address: lcvisser@ucdavis.edu.Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Ave, Davis, CA, 95616, USA.Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Ave, Davis, CA, 95616, USA.Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Ave, Davis, CA, 95616, USA.Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Ave, Davis, CA, 95616, USA.Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Ave, Davis, CA, 95616, USA.Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, One Shields Ave, Davis, CA, 95616, USA.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31794914

Citation

Visser, L C., et al. "Echocardiographic Assessment of Right Heart Size and Function in Dogs With Pulmonary Valve Stenosis." Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology, vol. 26, 2019, pp. 19-28.
Visser LC, Nishimura S, Oldach MS, et al. Echocardiographic assessment of right heart size and function in dogs with pulmonary valve stenosis. J Vet Cardiol. 2019;26:19-28.
Visser, L. C., Nishimura, S., Oldach, M. S., Bélanger, C., Gunther-Harrington, C. T., Stern, J. A., & Hsue, W. (2019). Echocardiographic assessment of right heart size and function in dogs with pulmonary valve stenosis. Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology, 26, pp. 19-28. doi:10.1016/j.jvc.2019.11.002.
Visser LC, et al. Echocardiographic Assessment of Right Heart Size and Function in Dogs With Pulmonary Valve Stenosis. J Vet Cardiol. 2019;26:19-28. PubMed PMID: 31794914.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Echocardiographic assessment of right heart size and function in dogs with pulmonary valve stenosis. AU - Visser,L C, AU - Nishimura,S, AU - Oldach,M S, AU - Bélanger,C, AU - Gunther-Harrington,C T, AU - Stern,J A, AU - Hsue,W, Y1 - 2019/11/14/ PY - 2019/05/13/received PY - 2019/10/28/revised PY - 2019/11/04/accepted PY - 2019/12/4/pubmed PY - 2019/12/4/medline PY - 2019/12/4/entrez KW - Canine KW - Pulmonic stenosis KW - Right ventricular function KW - Tricuspid annular plane systolic excursion SP - 19 EP - 28 JF - Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology JO - J Vet Cardiol VL - 26 N2 - INTRODUCTION/OBJECTIVES: We sought to determine the prevalence and clinical significance of right heart remodeling and right ventricular (RV) dysfunction in dogs with pulmonary valve stenosis (PS). We also sought to evaluate repeatability of several measurements of severity of PS, right heart size, and RV function in dogs with PS. ANIMALS, MATERIALS AND METHODS: Several indices of right atrial (RA) size and RV size and function were prospectively evaluated in 48 dogs with PS. Regression analysis was used to determine if indices of right heart size and function were independently associated with maximum transpulmonary pressure gradient (max PG) and adverse clinical findings (exercise intolerance, syncope, or right heart failure). Eight dogs underwent a second echocardiogram performed by the same operator to assess repeatability of the echocardiographic indices, which was quantified by coefficient of variation (CV) and repeatability coefficient. RESULTS: Increased RA size (81%), increased RV wall thickness (83%), and decreased tricuspid annular plane systolic excursion (TAPSE [81%]) were common. Right atrial size, end-diastolic RV area, and RV wall thickness were independently associated with max PG. Decreased TAPSE was independently associated with adverse clinical findings. All indices except RA area (18.6%) and RV systolic velocity (20.7%) had CVs <15%. Repeatability coefficients are available to help distinguish a true change versus measurement variability during serially obtained exams. CONCLUSIONS: Right heart remodeling and RV dysfunction are common in dogs with PS and are associated with echocardiographic and clinical severity. Results support the quantitative assessment of right heart size and function in dogs with PS. SN - 1875-0834 UR - https://www.unboundmedicine.com/medline/citation/31794914/Echocardiographic_assessment_of_right_heart_size_and_function_in_dogs_with_pulmonary_valve_stenosis L2 - https://linkinghub.elsevier.com/retrieve/pii/S1760-2734(19)30143-2 DB - PRIME DP - Unbound Medicine ER -