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Analyzing the toxicity of bisphenol-A to microalgae for ecotoxicological applications.
Environ Monit Assess. 2019 Dec 03; 192(1):8.EM

Abstract

Bisphenol-A (BPA) is a chemical used in the production of polycarbonate plastic and epoxy resins that may be related to the occurrence of human endocrine disorders. The present study aims to indicate a microalgae for use in ecotoxicological tests concerning BPA contamination of aquatic environments by analyzing its toxicity for the freshwater species Pseudokirchneriella subcapitata, and the two marine species Tetraselmis chuii and Skeletonema costatum. The standardization of the test involved determination of suitable nominal concentrations of BPA and the most appropriate species for use as biomarkers. S. costatum and P. subcapitata demonstrated resistance to BPA, features that are not of interest for toxicity markers. T. chuii presented an adequate sensitivity to BPA, compatible with parameters used in human toxicology for this substance, and is indicated as a potential biomarker for the presence of BPA in marine environments. The IC50 of T. chuii was 2.5 μM with R2 = 0.9, indicating reliability to demonstrate that low concentrations of BPA has significant toxicity to this species.

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Authors+Show Affiliations

Falcão VGO
Instituto de Biologia, Universidade Federal da Bahia, Rua Barão de Jeremoabo, 147, Salvador, BA, 40170-290, Brazil.
Carneiro DC
Instituto de Biologia, Universidade Federal da Bahia, Rua Barão de Jeremoabo, 147, Salvador, BA, 40170-290, Brazil.
Pereira SA
Instituto de Biologia, Universidade Federal da Bahia, Rua Barão de Jeremoabo, 147, Salvador, BA, 40170-290, Brazil.
da Silva MRD
Universidade Federal de São Paulo, Rua Pedro de Toledo, 669, São Paulo, SP, 04032-032, Brazil.
Candé AA
Instituto de Biologia, Universidade Federal da Bahia, Rua Barão de Jeremoabo, 147, Salvador, BA, 40170-290, Brazil.
da Cunha Lima ST
Instituto de Biologia, Universidade Federal da Bahia, Rua Barão de Jeremoabo, 147, Salvador, BA, 40170-290, Brazil. stcunhalima@ufba.br.

MeSH

Benzhydryl CompoundsChlorophytaDiatomsEcotoxicologyFresh WaterMicroalgaePhenolsReproducibility of ResultsWater Pollutants, Chemical

Pub Type(s)

Journal Article

Language

eng

PubMed ID

31797148

Citation

Falcão, Valéria Gomes Oliveira, et al. "Analyzing the Toxicity of bisphenol-A to Microalgae for Ecotoxicological Applications." Environmental Monitoring and Assessment, vol. 192, no. 1, 2019, p. 8.
Falcão VGO, Carneiro DC, Pereira SA, et al. Analyzing the toxicity of bisphenol-A to microalgae for ecotoxicological applications. Environ Monit Assess. 2019;192(1):8.
Falcão, V. G. O., Carneiro, D. C., Pereira, S. A., da Silva, M. R. D., Candé, A. A., & da Cunha Lima, S. T. (2019). Analyzing the toxicity of bisphenol-A to microalgae for ecotoxicological applications. Environmental Monitoring and Assessment, 192(1), 8. https://doi.org/10.1007/s10661-019-7984-0
Falcão VGO, et al. Analyzing the Toxicity of bisphenol-A to Microalgae for Ecotoxicological Applications. Environ Monit Assess. 2019 Dec 3;192(1):8. PubMed PMID: 31797148.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Analyzing the toxicity of bisphenol-A to microalgae for ecotoxicological applications. AU - Falcão,Valéria Gomes Oliveira, AU - Carneiro,Diego de Carvalho, AU - Pereira,Solange Andrade, AU - da Silva,Magnus Régios Dias, AU - Candé,Antônio Alfa, AU - da Cunha Lima,Suzana Telles, Y1 - 2019/12/03/ PY - 2019/06/28/received PY - 2019/11/22/accepted PY - 2019/12/5/entrez PY - 2019/12/5/pubmed PY - 2020/1/17/medline KW - Ecotoxicology KW - Endocrine disruptor KW - Inhibitory concentration KW - Plastic SP - 8 EP - 8 JF - Environmental monitoring and assessment JO - Environ Monit Assess VL - 192 IS - 1 N2 - Bisphenol-A (BPA) is a chemical used in the production of polycarbonate plastic and epoxy resins that may be related to the occurrence of human endocrine disorders. The present study aims to indicate a microalgae for use in ecotoxicological tests concerning BPA contamination of aquatic environments by analyzing its toxicity for the freshwater species Pseudokirchneriella subcapitata, and the two marine species Tetraselmis chuii and Skeletonema costatum. The standardization of the test involved determination of suitable nominal concentrations of BPA and the most appropriate species for use as biomarkers. S. costatum and P. subcapitata demonstrated resistance to BPA, features that are not of interest for toxicity markers. T. chuii presented an adequate sensitivity to BPA, compatible with parameters used in human toxicology for this substance, and is indicated as a potential biomarker for the presence of BPA in marine environments. The IC50 of T. chuii was 2.5 μM with R2 = 0.9, indicating reliability to demonstrate that low concentrations of BPA has significant toxicity to this species. SN - 1573-2959 UR - https://www.unboundmedicine.com/medline/citation/31797148/Analyzing_the_toxicity_of_bisphenol_A_to_microalgae_for_ecotoxicological_applications_ DB - PRIME DP - Unbound Medicine ER -